Doxorubicin-dependent reduction of ferrylmyoglobin and inhibition of lipid peroxidation: Implications for cardiotoxicity of anticancer anthracyclines

Chemical Research in Toxicology

Volumn 15, Issue 9, 2002, Pages 1179-1189

  Menna, Pierantonio ^a   Salvatorelli, Emanuela ^a   Giampietro, Rossella ^a   Liberi, Giovanni ^a   Teodori, Giovanni ^a   Calafiore, Antonio M ^a   Minotti, Giorgio ^a  

^a UNIVERSITY OF CHIETI   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

2,2' AZOBIS(2 AMIDINOPROPANE); ACLARUBICIN; ADRIAMYCINONE; ANTHRACYCLINE; ARACHIDONIC ACID; ASCORBIC ACID; DAUNORUBICIN; DOXORUBICIN; FERRYLMYOGLOBIN; FREE RADICAL; GLUTATHIONE; HYDROGEN PEROXIDE; HYDROQUINONE; IDARUBICIN; METMYOGLOBIN; MYOGLOBIN; NAPHTHAZARIN; PEROXY RADICAL; SCAVENGER; THIOBARBITURIC ACID REACTIVE SUBSTANCE; THIONEINE;

ANTIOXIDANT ACTIVITY; ARTICLE; CARDIOTOXICITY; COMPETITIVE INHIBITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOSOL; DECOMPOSITION; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; HEART MUSCLE BIOPSY; HORSE; HUMAN; HUMAN TISSUE; IC 50; IN VITRO STUDY; LIPID PEROXIDATION; REDUCTION; SPECTROSCOPY;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; ARACHIDONIC ACID; DOXORUBICIN; FREE RADICALS; HEART; HORSES; HUMANS; HYDROGEN PEROXIDE; INHIBITORY CONCENTRATION 50; IRON; KINETICS; LIPID PEROXIDATION; METMYOGLOBIN; MYOCARDIUM; OXIDATION-REDUCTION; STATISTICS;

EQUUS CABALLUS;

EID: 0036740046     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx020055+     Document Type: Article

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