Combination of autoantibody markers and risk for development of type 1 diabetes: Results from a large French cohort of family members

Diabetes and Metabolism

Volumn 28, Issue 4 I, 2002, Pages 279-285

  Thivolet, C ^a   Nicolino, M ^a   Monbeig, S ^a   Estour, B ^a   Halimi, S ^a   Robert, M ^a   Orgiazzi, J ^a   Chatelain, P ^a  

^a EDOUARD HERRIOT HOSPITAL   (France)

Author keywords

Diabetes; Immunology; Prediction

Indexed keywords

AUTOANTIBODY; HLA DQ ANTIGEN; INSULIN ANTIBODY;

ALLELE; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DISEASE MARKER; FAMILY; FRANCE; GENETIC SUSCEPTIBILITY; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR CLINICAL STUDY; MASS SCREENING;

AUTOANTIBODIES; BIOLOGICAL MARKERS; COHORT STUDIES; DIABETES MELLITUS, TYPE 1; FAMILY; FEMALE; FOLLOW-UP STUDIES; FRANCE; HUMANS; ISLETS OF LANGERHANS; MALE; PREDICTIVE VALUE OF TESTS; RISK; RISK FACTORS; SIBLINGS; TIME FACTORS;

EID: 0036739276     PISSN: 12623636     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. The Diabetes Control and Complications Trial Research Group. The Effect of Intensive Treatment of Diabetes on the Development and Progression of Long-Term Complications in Insulin-Dependent Diabetes Mellitus. N Engl J Med. 1993, 329, 977-986.
2. Notkins AL, Lernmark A. Autoimmune Type I diabetes: Resolved and unresolved issues, J Clin Invest, 2001, 108, 1247-1252.
3. Thivolet C. New therapeutic approaches to type 1 diabetes: from prevention to cellular or gene therapies. Clin Endocrinol, 2001, 55, 565-574.
4. Gepts W. Pathologic anatomy of the pancreas in juvenile diabetes mellitus. Diabetes, 1965, 14, 619-633.
5. Notkins AL, Lemmark A. Autoimmune type 1 diabetes: resolved and unresolved issues. J Clin Invest, 2001, 108, 1247-1252.
6. Bottazzo GF, Florin-Christensen A, Doniach D. Islet cell antibodies in diabetes mellitus with autoimmune polyendocrine deficiencies. Lancet, 1974, 2, 1279-1283.
7. Baekkeskov S, Aanstoot HJ, Christgau S, Reetz A, Solimena M, Cascalho M, Folli F, Richter-Olesen H, DeCamilli P, Camilli PD. Identification of the 64K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase. Nature, 1990, 347, 151-156.
8. Lan MS, Wasserfall C, Maclaren NK, Notkins AL. IA-2, a transmembrane protein of the protein tyrosine phosphatase family, is a major autoantigen in insulin-dependent diabetes mellitus. Proc Natl Acad Sci USA, 1996, 93, 6367-6370.
9. Martin S, Wolf-Eichbaum D, Duinkerken G, Scherbaum WA, Kolb H, Noordzij JG, Roep BO. Development of type 1 diabetes despite severe hereditary B-lymphocyte deficiency. N Engl J Med, 2001, 345, 1036-1040.
10. Imagawa A, Hanafusa T, Tamura S, Moriwaki M, Itoh N, Yamamoto K, Iwahashi H, Yamagata K, Waguri M, Nanmo T, Uno S, Nakajima H, Namba M, Kawata S, Miyagawa JI, Matsuzawa Y. Pancreatic biopsy as a procedure for detecting in situ autoimmune phenomena in type 1 diabetes: close correlation between serological markers and histological evidence of cellular autoimmunity. Diabetes, 2001, 50, 1269-1273.
11. Sabbah E, Savola K, Ebeling T, Kulmala P, Vahasalo P, Ilonen J, Salmela PI, Knip M. Genetic, autoimmune, and clinical characteristics of childhood- and adult-onset type 1 diabetes. Diabetes Care, 2000, 23, 1326-1332.
12. Seissler J, de Sonnaville JJ, Morgenthaler NG, Steinbrenner H, Glawe D, Khoo-Morgenthaler UY, Lan MS, Notkins AL, Heine RJ, Scherbaum WA. Immunological heterogeneity in type I diabetes: presence of distinct autoantibody patterns in patients with acute onset and slowly progressive disease. Diabetologia, 1998, 41, 891-897.
13. Thivolet C, Beaufrere B, Betuel H, Gebuhrer L, Chatelain P, Durand A, Toumiaire J, Francois R. Islet cell and insulin autoantibodies in subjects at high risk for development of type 1 (insulin-dependent) diabetes mellitus: the Lyon family study. Diabetologia, 1988, 31, 741-746.
14. Thivolet CH, Tappaz M, Durand A, Petersen J, Stefanutti A, Chatelain P, Vialettes B, Scherbaum W, Orgiazzi J. Glutamic acid decarboxylase (GAD) autoantibodies are additional predictive markers of type I (insulin-dependent) diabetes mellitus in high risk individuals. Diabetologia, 1992, 35, 570-576.
15. American Diabetes Association. Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Diabetes Care, 1997, 20, 1183-1197.
16. Petersen JS, Hejnaes KR, Moody A, Karlsen AE, Marshall MO, Hoier-Madsen M. Boel E, Michelsen BK, Dyrberg T. Detection of GAD65 antibodies in diabetes and other autoimmune diseases using a simple radioligand assay. Diabetes, 1994, 43, 459-467.
17. Panicot L, Mas E, Thivolet C, Lombardo D. Circulating antibodies against an exocrine pancreatic enzyme in type I diabetes. Diabetes, 1999, 48, 2316-2323.
18. Bingley PJ, Christie MR, Bonifacio E, Bonfanti R, Shattock M, Fonte MT, Bottazzo GF, Gale EA. Combined analysis of autoantibodies improves prediction of 1DDM in islet cell antibody positive relatives. Diabetes, 1994, 43, 1304-1310.
19. Verge CF. Stenger D, Bonifacio E, Colman PG, Pilcher C, Bingley PJ, Eisenbarth GS. Combined use of autoantibodies (IA-2 autoantibody, GAD autoantibody, insulin autoantibody, cytoplasmic islet cell antibodies) in type 1 diabetes: Combinatorial Islet Autoantibody Workshop, Diabetes, 1998, 47, 1857-1866.
20. Dittler J, Seidel D, Schenker M, Ziegler AG. GAD IA-2 combi determination as first line screening for improved prediction of type 1 diabetes in relatives. Diabetes, 1998, 47, 592-598.
21. Pastore MR, Bazzigulappi E, Bonfanti R, Dozio N, Sergi A, Balini A, Belloni C, Meschi F, Bonifacio E, Bosi E. Two step islet autoantibody screening for risk assessment of type 1 diabetes in relatives. Diabetes Care, 1998, 21, 1445-1450.
22. Ziegler AG, Hummel M, Schenker M, Bonifacio E. Autoantibody appearance and risk for development of childhood diabetes in offspring of parents with type 1 diabetes: the 2-year analysis of the German BABYDIAB Study. Diabetes, 1999, 48, 460-468.
23. Rewers M, Bugawan TL, Norris JM, Blair A, Beaty B, Hoffman M, McDuffie RS Jr, Hamman RF, Klingensmith G, Eisenbarth GS, Erlich HA. Newborn screening for HLA markers associated with IDDM: diabetes autoimmunity study in the young (DAISY). Diabetologia, 1996, 39, 807-812.
24. Kupila A, Muona P, Simell T, Arvilommi P, Savolainen H, Hämäläinen AM, Korhonen S, Kimpimäki T, Sjöroos M, Ilonen J, Knip M, Simell O. Feasibility of genetic and immunological prediction of type 1 diabetes in a population based cohort. Diabetologia, 2001, 44, 290-297.
25. Martin S, Wolf-Eichbaum D, Duinkerken G, Scherbaum WA, Kolb H, Noordzij JG, Roep BO. Development of type 1 diabetes despite severe hereditary B-lymphocyte deficiency. N Engl J Med. 2001, 345, 1036-1040.
26. Davies JL, Kawaguchi Y, Benett ST, Copeman JB, Cordell HJ, Pritchard LE, Reed PW, Gough SCL, Jenkins SC, Palmer SM, Balfour KM, Rowe BR, Farrall M, Barnett AH. Bain SC, Todd JA. A genome wide search for human type 1 diabetes susceptibility genes. Nature, 1999, 371, 130-136.
27. Serjeantson SW, Court J, Mackay IR, Matheson B, Rowley MJ, Tuomi T. Wilson JD, Zimmer P. HLA-DQ genotypes are associated with autoimmunity to GAD in IDDM patients. Hum Immunol, 1993, 38, 97-104.
28. Genovese S, Bonfanti R, Bazzigaluppi E, Lampasona V. Benazzi E, Bosi E, Chiumello G, Bonifacio E. Association of IA-2 autoantibodies with the HLA DR4 phenotypes in IDDM, Diabetologia, 1996, 39, 1223-1226.
29. Kulmala P, Rahko J, Savola K, Vahasalo P, Veijola R, Sjoroos M, Reunanen A, Ilonen J, Knip M. Stability of autoantibodies and their relation to genetic and metabolic markers of Type I diabetes in initially unaffected schoolchildren. Diabetologia, 2000, 43, 457-464.
30. Nejentsev S, Sjoroos M, Soukka T, Knip M, Simell O, Lovgren T, Ilonen J. Population-based genetic screening for the estimation of Type I diabetes mellitus risk in Finland: selective genotyping of markers in the HLA-DQB1, HLA-DQA1 and HLA-DRB1 loci. Diabet Med. 1999, 16, 985-992.
31. Rewers M, Bugawan TL, Norris JM, Blair A, Beaty B, Hoffman M, McDuffie RS Jr, Hamman RF, Klingensmith G, Eisenbarth GS, Erlich HA. Newborn screening for HLA markers associated with IDDM: diabetes autoimmunity study in the young (DAISY). Diabetologia, 1996, 39, 807-812.