Brain metastasis from hepatocellular carcinoma associated with hepatitis B virus

Journal of Experimental and Clinical Cancer Research

Volumn 21, Issue 3, 2002, Pages 321-327

  Frati, Alessandro ^a   Salvati, M ^a   Giarnieri, E ^a   Santoro, A ^a   Rocchi, G ^a   Frati, L ^a  

^a NONE   (Italy)

Author keywords

Brain metastasis; Hepatitis B virus; Hepatocellular carcinoma; P16; P53; PRB

Indexed keywords

GENE PRODUCT; MONOCLONAL ANTIBODY; PROTEIN P16; PROTEIN P53; PROTEIN X; RETINOBLASTOMA PROTEIN; VIRUS PROTEIN;

ADULT; AGED; ARTICLE; BRAIN METASTASIS; CANCER INHIBITION; CANCER INVASION; CANCER LOCALIZATION; CASE REPORT; DISEASE ASSOCIATION; ENDEMIC DISEASE; FEMALE; HEPATITIS B; HEPATITIS B VIRUS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; MALE; NEUROSURGERY; ONCOGENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR SUPPRESSOR GENE;

AGED; BRAIN NEOPLASMS; CARCINOMA, HEPATOCELLULAR; CYCLIN-DEPENDENT KINASE INHIBITOR P16; FEMALE; HEPATITIS B; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VIRUS; HUMANS; LIVER CIRRHOSIS; LIVER NEOPLASMS; MALE; MIDDLE AGED; RETINOBLASTOMA PROTEIN; TUMOR MARKERS, BIOLOGICAL; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0036738578     PISSN: 03929078     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (50)

1. Asahara T., Yano M., Fukuda S., Fukuda T., Nakahara H., Katayama K., Itamoto T., Dohi K., Nakanishi T., Kitamoto M., Azuma K., Ito K., Moriwaki K., Yuge O., Shimamoto F.: Brain metastasis from hepatocellular carcinoma after radical hepatectomy. Hiroshima J. Med. Sci. 48:91-94, 1999.
2. Bindal R., Sawaya R., Leavens M.E., Lee J.J.: Surgical treatment of multiple brain metastases. J. Neurosurg. 79:210-216, 1993.
3. Bressac B., Galvin K.M., Liang T.J., Isselbacher K.J., Wands J.R., Ozturk M.: Abnormal structure and expression of p53 gene in human hepatocellular carcinoma. Proc. Natl. Acad. Sci. USA 87:1973-1977, 1990.
4. Carr I.B., Flickinger J.C., Lotze M.T.: Hepatobiliary cancers in De Vita..(ed): Cancer pp 1087-1113, 1997.
5. Chang Y.C., Chen R.C.: Craniospinal and cerebral metastasis of primary hepatomas. J. Formosan. Med. Assoc. 78:594-604, 1979.
6. Chen S.C., Lian S.L., Chuang W.L., Hsieh M.Y., Wang L.Y., Chang W.Y., Ho Y.H.: Radiotherapy in the treatment of hepatocellular carcinoma and its metastases. Cancer Chemother. Pharmacol. 31 Suppl.: S103-105, 1992.
7. Chin P.L., Chu D.Z., Clarke K.G., Odom-Maryon T., Yen Y., Wagman L.D.: Ethnic differences in the behavior of hepatocellular carcinoma. Cancer 85:1931-1936, 1999.
8. Farshid M., Nedjar S., Mitchell F., Biswas R.: Effect of hepatitis B virus X protein on the expression of retinoblastoma gene product. Acta Virologica 41:125-129, 1997.
9. Feitelson M.A.: Hepatitis B x antigen and p53 in the development of hepatocellular carcinoma. J. Hepatobiliary Pancreat. Surg. 5:367-374, 1998.
10. Feitelson M.A., Zhu M., Duan L.X., London W.T.: Hepatitis B x antigen and p53 are associated in vitro and in liver tissues from patients with primary hepatocellular carcinoma. Oncogene 8:1109-1117, 1993.
11. Foster P.L., Eisenstadt E., Miller J.H.: Base substitution mutations induced by metabolically activated aflatoxin B1. Proc. Natl. Acad. Sci. USA 80:2695-2698, 1983.
12. Friedman H.D.: Hepatocellular carcinoma with central nervous system metastasis: a case report and literature review. Med. Pediatr. Oncol. 19:139-144, 1991.
13. Harper J.W., Elledge S.J.: Cdk inhibitors in development and cancer. Curr. Opin. Genet. Dev. 6:56-64, 1996.
14. Horie Y., Maeda N., Kawasaki H., Suyama A.: Characteristic differences of hepatocellular carcinoma in Japan, with special reference to liver weight at autopsy. Hepatogastroenterology 44:1407-1412, 1997.
15. Hsia C.C., Di Bisceglie A.M., Kleiner D.E Jr., Farshid M., Tabor E.: RB tumor suppressor gene expression in hepatocellular carcinomas from patients infected with the hepatitis B virus. J. Med. Virol. 44:67-73, 1994.
16. Hsia C.C., Kleiner D.E Jr., Axiotis C.A., Di Bisceglie A., Nomura A.M., Stemmermann G.N., Tabor E.: Detection of p53 mutations by immunohistochemistry in hepatocellular carcinoma: association with hepatitis B virus in patients from high and low aflatoxin regions. J. Natl. Canc. Inst. 84:1638-1641, 1992.
17. Hsu I.C., Metcalf R.A., Sun T., Welsh J.A., Wang N.J., Harris C.C.: Mutational hotspot in the p53 gene in human hepatocellular carcinomas. Nature 350:427-428, 1991.
18. Hui A.M., and Makuuchi M.: Molecular basis of multistep hepatocarcinogenesis: genetic and epigenetic events. Scand. J. Gastroenterol. 8:737-742, 1999.
19. Hui A.M., Li X., Makuuchi M., Takayama T., Kubota K.: Overexpression and lack of retinoblastoma protein are associated with tumor progression and metastasis in hepatocellular carcinoma. Int. J. Cancer 84:604-608, 1999.
20. Hui A.M., Makuuchi M., Li X.: Cell cycle regulators and human hepatocarcinogenesis. Hepato-Gastroenterology 45:1635-1642, 1998.
21. Hui A.M., Sun L., Kanai Y.: Inactivation of p16ink4 in hepatocellular carcinoma. Hepatology 24:575-579, 1996.
22. Jia L., Wang X.W., Harris C.C.: Hepatitis B virus X protein inhibits nucleotide excision repair. Int. J. Cancer 80:875-879, 1999.
23. Kim M., Na D.L., Park S.H., Jeon B.S., Roh J.K.: Nervous system involvement by metastatic hepatocellular carcinoma. J. Neurooncol. 36:85-90, 1998
24. Kuga Y., Waga S., Itoh H.: Intracranial hemorrhage due to brain metastasis from hepatocellular carcinoma-case report. Neur. Med. Chir. (Tokyo) 30:768-771, 1990.
25. Kutluk T., Buyukpamukcu M., Sarialioglu F., Akyuz C. Re: "Hepatocellular carcinoma with central nervous system metastasis" by Friedman. Med. Pediatr. Oncol. 21:380-381, 1993.
26. Lee J.P., Lee S.T.: Hepatocellular carcinoma presenting as intracranial metastases. Surg. Neurol. 30:316-320, 1998.
27. Loo K.T., Tsui W.M., Chung K.H., Ho L.C., Tang S.K., Tse C.H.: Hepatocellular carcinoma metastasizing to the brain and orbit: report of three cases. Pathology 26:119-122, 1994.
28. Murakami Y., Hayashi K., Hiroashi S., Sekiya T.: Aberrations of the tumor suppressor p53 and retinoblastoma genes in human hepatocellular carcinomas. Cancer Res. 51:5520-5525, 1991.
29. Murakami K., Nawano S., Moriyama N., Sekiguchi R., Satake M., Fujimoto H., Ichikawa T.: Intracranial metastases of hepatocellular carcinoma: CT and MRI. Neuroradiology 38:31-35, 1996.
30. Naka T., Toyota N., Kaneko T., Kaibara N.: Protein expression of p53, p21WAF1, and Rb as a prognostic indicators in patients with surgically treated hepatocellular carcinoma. Anticancer Res. 18:555-564, 1998.
31. Nakashima T., Okuda K., Kojiro M., Jimi A., Yamaguchi R., Sakamoto K., Ikari T.: Pathology of hepatocellular carcinoma in Japan. 232 consecutive cases autopsied in ten years. Cancer 51:863-877, 1983.
32. Nishida N., Fukuda Y., Komeda T., Kita R., Sando T., Furukawa M., Amenomori M., Shibagaki I., Nakao K., Ikenaga M.: Amplification and over expression of the cyclin D1 Gene in aggressive human hepatocellular carcinoma. Cancer Research 54:3107-3110, 1994.
33. Okuda K.: Hepatocellular carcinomas associated with hepatitis B and C virus infections: are they any different? Hepatology 22:1883-1884, 1995.
34. Peres M.F., Forones N.M., Malheiros S.M., Ferraz H.B., Stavale J.N., Gabbai A.A.: Hemorragic cerebral metastasis as first manifestation of a hepatocellular carcinoma. Case report. Arq. Neuropsiquiatr. 56:658-660, 1998.
35. Phadke J.G., Hughes R.C.: Hepatocellular carcinoma with cranial metastasis and hyperglobulinaemia. J Neurol Neurosurg Psychiatry 44:1171-1172, 1981.
36. Rossner M.T.: Review: hepatitis B virus X gene product: a promiscuous transcriptional activator. J. Med. Virol. 36:101-117, 1992.
37. Rubin E., Farber J.L.: The liver and biliary system, in Rubin E and Farber JL (ed): Pathology. Philadelphia. New York: Lippincott Raven, pp 757-838, 1999.
38. Sato Y., Itoh F., Hareyama M., Satoh M., Hinoda Y., Seto M., Ueda R., Imai K.: Association of cyclin D1 expression with factors correlated tumor progression in human hepatocellular carcinoma. J. Gastroenterology 34:486-493, 1999.
39. Sherr C.J., Roberts J.M.: Inhibitors of mammalian G1 cyclin dependent kinase. Genes Dev. 9:1149-1163, 1995.
40. Shuangshoti S., Rungruxsirivorn S., Panyathanya R.: Intracranial metastasis of hepatic carcinomas: a study of 9 cases within 28 years. J. Med. Assoc. Thai. 72:307-313, 1989.
41. Slage B.L.: P53 mutations and hepatitis B virus: cofactors in hepatocellular carcinoma. Hepatology 21:597-599, 1995.
42. Slagle B.L., Zhou Y., Butel J.S.: Hepatitis B virus integration event in human chromosome 17p near the p53 identifies the region of the chromosome commonly deleted in virus-positive hepatocellular carcinomas. Cancer Res. 51:49-54, 1991.
43. Tabor E.: Tumor suppressor genes, growth factor genes, and oncogenes in hepatitis B virus-associated hepatocellular carcinoma. J. Med. Virol. 42:357-365, 1994.
44. Tabor E.: Hepatocarcinogenesis: hepatitis viruses and altered tumor suppressor gene function. Princess Takamatsu Symp 25:151-161, 1995.
45. Tanabe H., Kondo A., Kinuta Y., Matsuura N., Hasegawa K., Chin M., Saiki M.: Unusual presentation of brain metastasis from hepatocellular carcinoma-two case reports. Neurol. Med. Chir. (Tokyo) 34:748-753, 1994.
46. Ueda H., Ullrich S.J., Gangemi J.D., Kappel C.A., Ngo L., Feitelson M.A., Jay G.: Functional inactivation but not structural mutation of p53 causes liver cancer. Nat. Genet. 9:41-47, 1995.
47. Volkmann M., Hofmann W.J., Muller M., Rath U., Otto G., Zentgraf H., Galle P.R: P53 overexpression is frequent in european hepatocellular carcinoma and largely independent of the codon 249 hotspot mutation. Oncogene 9:195-204, 1994.
48. Wakisaka S., Tashiro M., Nakano S., Kita T., Kisanuki H., Kinoshita K.: Intracranial and orbital metastasis of hepatocellular carcinoma: report of two cases. Neurosurgery 26:863-866, 1990.
49. Yen F.S., Wu J.C., Lai C.R., Sheng W.Y., Kuo B.I., Chen T.Z., Tsay S.H., Lee S.D.: Clinical and radiological pictures of hepatocellular carcinoma with intracranial metastasis. J. Gastroenterol. Hepatol. 10:413-418, 1995.
50. Zubler M.A., Rivera R., Lane M.: Hepatoma presenting as a retro-orbital metastasis. Cancer 15:1883-1885, 1981.