Differential characterization of women with vulvar vestibulitis syndrome

American Journal of Obstetrics and Gynecology

Volumn 187, Issue 3, 2002, Pages 589-594

  Witkin, Steven S ^a   Gerber, Stefan ^a   Ledger, William J ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Candida; Human papillomavirus; Interleukin 1 receptor antagonist gene polymorphism; Vulvar vestibulitis syndrome

Indexed keywords

INTERLEUKIN 1 RECEPTOR BLOCKING AGENT;

ADULT; ARTICLE; CHEEK MUCOSA; CLINICAL FEATURE; DIFFERENTIAL DIAGNOSIS; DNA POLYMORPHISM; DYSURIA; FEMALE; GENETIC VARIABILITY; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; QUESTIONNAIRE; VAGINA CANDIDIASIS; VAGINA DISCHARGE; VESTIBULAR DISORDER; VULVAR VESTIBULITIS; WART VIRUS;

EID: 0036737747     PISSN: 00029378     EISSN: None     Source Type: Journal    
DOI: 10.1067/mob.2002.125889     Document Type: Article

References (26)

1. Friedrich EG. Vulvar vestibulitis. J Reprod Med 1987;32:110-4.
2. Foster DC, Woodruff JD. Case-control study of vulvar vestibulitis syndrome. J Womens Health 1995;4:677-80.
3. Jeremias J, Ledger WJ, Witkin SS. Interleukin 1 receptor antagonist gene polymorphism in women with vulvar vestibulitis. Am J Obstet Gynecol 2000;182:283-5.
4. Rider LG, Artlett CM, Foster CB, Ahmed A, Neeman T, Chanock SJ, et al. Polymorphisms in the IL-1 receptor antagonist gene VNTR are possible risk factors for juvenile idiopathic inflammatory myopathies. Clin Exp Immunol 2000;121:47-52.
5. Tarlow JK, Clay FE, Cork MJ, Blakemore AF, McDonash AJ, Messenger AG, et al. Severity of alopecia areata is associated with a polymorphism in the interleukin-1 receptor antagonist gene. J Invest Dermatol 1994;103:387-90.
6. Mansfield JC, Holden H, Tarlow JK, diGiovine FS, McDowell TL, Wilson AG, et al. Novel genetic association between ulcerative colitis and the anti-inflammatory cytokine interleukin-I receptor antagonist. Gastroenterology 1994;106:637-42.
7. Bioque G, Bouma G, Crusius JBA, Koutroutroubakis I, Kotense PJ, Menwissen SG, et al. Evidence for genetic heterogeneity in IBD: 1. The interelukin-1 receptor antagonist in the predisposition to suffer from ulcerative colitis. Eur J Gastroenterol Hepatol 1996;8:105-10.
8. Heresbach D, Alizadeh M, Dabadie A, LeBerre N, Colombel JF, Yaouang J, et al. Significance of interleukin-1beta and interleukin-1 receptor antagonist genetic polymorphism in inflammatory bowel diseases. Am J Gastroenterol 1997;92:1164-9.
9. Mann MS, Kaufman RH, Brown D, Adam E. Vulvar vestibulitis: significant clinical variables and treatment outcome. Obstet Gynecol 1992;79:22-5.
10. Sarma AV, Foxman B, Bayirli B, Haefner H, Sobel JD. Epidemiology of vulvar vestibulitis syndrome: an exploratory case-control study. Sex Transm Infect 1999;75:320-6.
11. Nyirjesy P. Vulvar vestibulitis syndrome: a post-infectious entity? Current Infectious Disease Reports 2000;2:531-5.
12. Baggish MS, Miklos JR. Vulvar pain syndrome: a review. Obstet Gynecol Surv 1995;50:618-27.
13. Ashman RB, Ott AK. Autoimmunity as a factor in recurrent vaginal candidosis and the minor vestibular gland syndrome. J Reprod Med 1989;34:264-6.
14. Bornstein J, Maman M, Abramovici H. "Primary" versus "secondary" vulvar vestibulitis: one disease, two variants. Am J Obstet Gynecol 2001;184:28-31.
15. Rogstad KE. Vulvar vestibulitis: aetiology, diagnosis and treatment. Int J STD AIDS 2000;11:557-62.
16. Gerber S, Bongiovanni AM, Ledger WJ, Witkin SS. A deficiency in interferon α production in women with vulvar vestibulitis. Am J Obstet Gynecol. 2002;186:361-4.
17. Gerber S, Bongiovanni AM, Ledger WJ, Witkin SS. Defective regulation of the pro-inflammatory immune response in women with vulvar vestibulitis syndrome. Am J Obstet Gynecol. 2002;186:696-700.
18. Ledger WJ, Kessler A, Leonard GH, Witkin SS. Vulvar vestibulitis - a complex clinical entity. Infect Dis Obstet Gynecol 1996;4:269-75.
19. Giraldo P, von Nowaskonski A, Gomes FA, Linhares I, Neves NA, Witkin SS. Vaginal colonization by Candida in asymptomatic women with and without a history of recurrent vulvovaginal candidiasis. Obstet Gynecol 2000;95:413-6.
20. Giraldo P, Neuer A, Korneeva IL, Ribeiro-Filho A, Simoes JA, Witkin SS. Vaginal heat shock protein expression in symptom-free women with a history of recurrent vulvovaginitis. Am J Obstet Gynecol 1999;180:524-9.
21. Asea A, Kraeft SK, Kurt-Jones EA, Stevenson MA, Chen LB, Finberg RW, et al. HSP70 stimulates cytokine production through a CD14-dependnet pathway, demonstrating its dual role as a chaperone and cytokine. Nat Med 2000;6:435-42.
22. Witkin SS, Gerber S, Ledger WJ. Influence of interleukin-1 receptor antagonist gene polymorphism on disease. Clin Infect Dis 2002;34:204-9.
23. Clay FE, Cork MJ, Tarlow JK, Blakemore AF, Harrington CI, Lewis F, et al. Interleukin 1 receptor antagonist gene polymorphism association with lichen schlerosus. Hum Genet 1994;94:407-10.
24. Tarlow JK, Cork MJ, Schmidt-Egenole M, Crane AM, Stierle C, Boehnke WH, et al. Association between interleukin-1 receptor antagonist gene polymorphism and early and late-onset psoriasis. Br J Dermatol 1997;136:147-8.
25. Horowitz BJ. Interferon therapy for condylomatous vulvitis. Obstet Gynecol 1989;73:446-8.
26. Nyirjesy P, Halpern M. Medical management of vulvar vestibulitis: results of a sequential treatment plan. Infect Dis Obstet Gynecol 1996;3:193-7.