Hyperthermic teratogenicity, thermal dose and diagnostic ultrasound during pregnancy: Implications of new standards on tissue heating

International Journal of Hyperthermia

Volumn 18, Issue 5, 2002, Pages 361-384

  Miller, M W ^a   Nyborg, W L ^b   Dewey, W C ^c   Edwards, M J ^d   Abramowicz, J S ^a   Brayman, A A ^e  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^b University of Vermont   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF SYDNEY   (Australia)

^e UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Birth defects; Diagnostic ultrasound; Neural tube defects; Thermal dose; Thermal Index

Indexed keywords

ACOUSTICS; BIRTH DEFECT; CORE TEMPERATURE; ECHOGRAPHY; EMBRYO (ANATOMY); EPIDEMIOLOGICAL DATA; EXPERIMENTAL ANIMAL; FETUS (ANATOMY); HEALTH CARE POLICY; HEALTH HAZARD; HEATING; HUMAN; HYPERTHERMIA; INFORMATION; MAMMAL; NEURAL TUBE DEFECT; NIDATION; NONHUMAN; OBSTETRIC CARE; PREGNANCY; RADIODIAGNOSIS; REVIEW; SAFETY; TEMPERATURE; TERATOGENESIS; TERATOGENICITY; THERMAL EXPOSURE; THERMAL TIME; ULTRASOUND; UNITED STATES;

ABNORMALITIES; ANIMALS; BODY TEMPERATURE; FEMALE; HEAT; HEATING; HUMANS; PREGNANCY; PREGNANCY OUTCOME; TEMPERATURE; TIME FACTORS; ULTRASONOGRAPHY, PRENATAL;

EID: 0036737355     PISSN: 02656736     EISSN: None     Source Type: Journal    
DOI: 10.1080/02656730210146890     Document Type: Review

References (123)

1. Biological consequences of hyperthermia
2. Thermal dose determination in cancer therapy
3. Variation in sensitivity to heat shock during the cell cycle of Chinese hamster cells in vitro
4. Arrhenius relationships from the molecule and cell to the clinic
5. Cellular responses to combinations of hyperthermia and radiation
6. Time-temperature relationship for hyperthermia induced stoppage of the microcirculation in tumors
7. Cell killing, chromosomal aberrations, and division delay as thermal sensitivity is modified during the cell cycle
8. Time-lapse cinemicrographic observations of heated G1-phase Chinese hamster ovary cells. I. Division probabilities and generation times
9. Intrinsic differences in heat and/or x-ray sensitivity of seven mammalian cell lines cultured and treated under identical conditions
10. The response of human and rodent cells to hyperthermia
11. Effects of acute exposures to elevated temperatures on rat embryo growth and development in vitro
12. Mitotic cell death and delay in mitotic activity in guinea pig embryos following brief maternal hyperthermia
13. Altered stress response in testis
14. Congenital defects in guinea pigs: Fetal resorptions, abortions, and malformations following induced hyperthermia during early gestation
15. Clinical disorders of fetal brain development: Defects due to hyperthermia
16. Hyperthermia and the induction of neural tube defects in mice
17. Hyperthermia as a teratogen: Parameters determining hyperthermia-induced head defects in the rat
18. Hyperthermia as a teratogen: A review of experimental studies and their clinical significance
19. Skeletal development following heat exposure in the rat
20. Sporadic malformations in laboratory animals and their influence on drug testing
21. Congenital malformations in the rat following induced hyperthermia during gestation
22. Teratologic study of rats exposed to ultrasound
23. Fetal and placental responses to artificially induced hyperthermia in rats
24. The induction of microphthalmia, encephalocele, and other head defects following hyperthermia during the gastrulation process in the rat
25. Exercise at high temperature causes maternal hyperthermia and fetal anomalies in rats
26. Congenital defects in guinea-pigs: Prenatal retardation of brain growth of guinea-pigs following hyperthermia during gestation
27. Induction of neural tube defects and skeletal malformations in mice following brief hyperthermia in utero
28. Trends in pregnancy rates for the United States, 1976-97: An update
29. Developmental abnormalities in the rat induced by heat shock
30. Abnormalities induced in cultured rat embryos by hyperthermia
31. Heat shock and thermotolerance during early rat embryo development
32. The effects of hyperthermia on the neuroepithelium of the 21-day guinea pig embryo: Histologic and ultrastructural study
33. Quantitative study of the effects of maternal hyperthermia on cell death and proliferation in the guinea pig brain on day 21 of pregnancy
34. Heat shock during rat embryo development in vitro results in decreased mitosis and abundant cell death
35. Growth and development of the brain in normal and heat-retarded guinea pigs
36. Heat shock genes and cell cycle regulation in early mammalian development
37. Heat shock affects cell cycling in the neural plate of cultured rat embryos: A flow cytometric study
38. Regulation of the inducible heat shock 71 genes in early neural development of cultured rat embryos
39. Growth and development of the brain and spinal cord of the guinea pig
40. Stage-specific homeotic vertebral transformations in mouse fetuses induced by maternal hyperthermia during somitogenesis
41. Vascular abnormalities due to hyperthermia in chick embryos
42. Uterine trauma and limb defects
43. Moebius unmasked: Pathogenesis of the moebius syndrome in an animal model
44. Congenital defects in guinea pigs following induced hyperthermia during gestation
45. Effects of acute exposure to elevated temperatures on rat embryo growth and development in vitro
46. Accumulation of heat shock protein 72 (hsp 72) in postimplantation rat embryos after exposure to various periods of hyperthermia (40-43° C) in vitro: Evidence that heat shock protein 72 is a biomarker of heat induced embryotoxicity
47. Embryonic development in vitro following short-duration exposure to heat
48. Relationship between abnormal somite development and axial skeletal defects in rats following heat exposure
49. Effects of pulsed ultrasound and temperature on the development of rat embryos in culture
50. The individual and combined effects of x-irradiation and hyperthermia on early somite mouse embryos in culture
51. Hyperthermia as a possible teratogenic agent
52. Risk factors for birth defects: Data from the Atlanta birth defects case-control study
53. Maternal heat exposure and neural tube defects
54. Effects of exposure to Finnish sauna
55. Maternal fever and birth outcome: A perspective study
56. Anencephaly in the Netherlands: A remarkable decline
57. Is recurrence rate of neural tube defects declining?
58. Recurrence rates for neural tube defects
59. Etiologic heterogeneity of neural-tube defects
60. Prevention of neural tube defects: Results of the Medical Research Council vitamin study
61. Prevention of the first occurrence of neural-tube defects by periconceptional vitamin supplementation
62. Anencephaly: Changes in prenatal detection and birth status, 1972-1990
63. The influence of prenatal ultrasound on the prevalence of congenital anomalies at birth
64. Influence of pulsewave ultrasonic irradiation on the prenatal development of mouse
65. The embryotoxic effects of ultrasound exposure on pregnant ICR mice
66. The combined effect of ultrasonic exposure and protein restriction on maternal and fetal mice
67. Developmental exposure of mice to pulsed ultrasound
68. Influence of Low-intensity ultrasonic irradiation on prenatal development of two inbred mouse strains
69. Effects of ultrasound on the mouse exposed at different stages of gestation: Acute studies
70. Testing for the teratogenicity of pulsed ultrasound in mice
71. Experimental studies on ultrasonic doppler method in obstetrics
72. Effect of pulsed low-power ultrasound on growing tissues. I. Developing mammalian and insect tissue
73. Effects of ultrasound on the prenatal development of the rat. Part I. 3.2 MHz continuous wave at nine days of gestation
74. A test for the effects of low-temporal-average-intensity pulsed ultrasound on the rat fetus
75. Temperature elevation in the rat fetus due to ultrasound exposure
76. Novel approach to evaluate the interaction of pulsed ultrasound with embryonic development
77. Ultrasonic teratology in mouse and man
78. The effects of pulsed ultrasound on the fetus
79. Ultrasound and the fetus
80. Evaluation of the bioeffects of prenatal ultrasound exposure in the cynomolgus macaque (Macaca fascicularis): I. Neonatal/infant observations
81. Evaluation of the bioeffects of prenatal ultrasound exposure in the cynomolgus macaque (Macaca fascicularis): II. Growth and behavior during the first year
82. WFUMB Symposium on Safety of Ultrasound in Medicine
83. Ultrasound contrast media and their use in obstetrics and gynecology
84. The American Institute of Ultrasound in Medicine and the Society of Radiologists in Ultrasound - Future directions in diagnostic ultrasound
85. Diagnostic ultrasound should be performed without upper intensity limits. Point-counter point
86. Effect of prenatal ultrasound screening on perinatal outcome. RADIUS study group
87. Case-control study of prenatal ultrasonography in children with delayed speech
88. Effects of frequent ultrasound during pregnancy: A randomised controlled trial
89. Routine ultrasound screening in pregnancy and the children's subsequent neurologic development
90. Current status of research in biophysical effects of ultrasound
91. IRPA/INIRC guidelines: Protection of the patient undergoing a magnetic resonance examination
92. Acoustic intensity measurements on ultrasonic diagnostic devices
93. Determination of acoustic power outputs in the microwatt-milliwatt range
94. Ultrasonic power and intensities produced by diagnostic ultrasound equipment
95. The output of pulse-echo equipment: A survey of powers, pressures and intensities
96. Patient-exposure data for doppler ultrasound in clinics
97. A review of therapeutic ultrasound: Effectiveness studies
98. Multiple malformations and exposure to therapeutic ultrasound during organogenesis
99. Output levels and bioeffects indices from diagnostic ultrasound exposure data reported to the FDA
100. Experimental validation of predicted temperature rises in tissue-mimicking materials
101. How reliable are manufacturer's reported acoustic output data?
102. The acoustic output of diagnostic machines
103. Thermotolerance in mammalian cells: A possible role for the heat shock proteins
104. The heat-shock proteins
105. Tansley review no. 51. Gene expression under temperature stress
106. In Vitro ultrasonic heating of fetal bone
107. Ultrasonic heating of the skull
108. Ultrasound heating in a tissue-bone phantom