Heat shock during rat embryo development in vitro results in decreased mitosis and abundant cell death

Reproductive Toxicology

Volumn 13, Issue 1, 1999, Pages 31-39

  Breen, J G ^a   Claggett, T W ^b   Kimmel, G L ^c   Kimmel, C A ^c  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^b CHARLES RIVER LABORATORIES   (United States)

^c U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Apoptosis; Cell cycle; Hyperthermia; Mitosis; Skeletal defects

Indexed keywords

CYCLINE; DNA; DNA NUCLEOTIDYLEXOTRANSFERASE; HEAT SHOCK PROTEIN;

ANIMAL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL CYCLE; CELL DEATH; CELL DIVISION; CELL PROLIFERATION; CONGENITAL MALFORMATION; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; FEMALE; FETUS DEVELOPMENT; HEAT SHOCK; HEAT SHOCK RESPONSE; HYPERTHERMIA; HYPERTHERMIC THERAPY; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; LIMB DEVELOPMENT; MALE; METABOLISM; MITOSIS; NONHUMAN; OPTIC DISK CUP; PATHOLOGY; PREGNANCY; RAT; RAT STRAIN; REPRODUCTIVE TOXICITY; TERATOGENESIS; THERMAL EXPOSURE;

ABNORMALITIES; ANIMALS; CELL DEATH; CELL DIVISION; DNA; DNA NUCLEOTIDYLEXOTRANSFERASE; EMBRYONIC AND FETAL DEVELOPMENT; FEMALE; HEAT-SHOCK RESPONSE; HYPERTHERMIA, INDUCED; IMMUNOHISTOCHEMISTRY; MALE; MITOSIS; PREGNANCY; PROLIFERATING CELL NUCLEAR ANTIGEN; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0032995177     PISSN: 08906238     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0890-6238(98)00056-2     Document Type: Article

References (25)

1. Edwards M.J., Shiota K., Smith M.S.R., Walsh D.A. Hyperthermia and birth defects. Repro Tox. 9:1995;411-425.
2. Shiota K. Neural tube defects and maternal hyperthermia in early pregnancy Epidemiology in a human embryo population . Am J Med Gene. 12:1982;281-288.
3. Edwards M.J. Congenital defects in guinea pigs following induced hyperthermia during gestation. Arch Pathol. 84:1967;42-48.
4. Edwards M.J. Congenital defects in guinea pigs fetal resorptions, abortions, and malformations following induced hyperthermia during early gestation . Teratology. 2:1969;213-228.
5. Edwards M.J. Congenital defects in guinea pigs prenatal retardation of brain growth of guinea pigs following hyperthermia during gestation . Teratology. 2:1969;329-336.
6. Webster W.S., Edwards M.J. Hyperthermia and the induction of neural tube defects in mice. Teratology. 29:1984;417-425.
7. Shiota K. Induction of neural tube defects and skeletal malformations in mice following brief hyperthermia in utero. Biol Neonate. 53:1988;86-97.
8. Aoyama N., Yamashina S. Cardiac and great vessel abnormalities in rat fetuses with external malformations induced by hyperthermia. Kaibogaku Zasshi. 69:(1):1994;34-41.
9. Mirkes P.E. Effects of acute exposures to elevated temperatures on rat embryo growth and development in vitro. Teratology. 32:1985;259-266.
10. Walsh D., Li K., Wass J., Dolnikov A., Zeng F., Zhe L., Edwards M. Heat-shock gene expression and cell cycle changes during mammalian development. Devel Gene. 14:1993;127-136.
11. Little S.A., Mirkes P.E. Clusterin expression during programmed and teratogen-induced cell death in the postimplantation rat embryo. Teratology. 52:1995;41-54.
12. Kimmel G.L., Cuff J.M., Kimmel C.A., Heredia D.J., Tudor N., Silverman P.M. Embryonic development in vitro following short-duration exposure to heat. Teratology. 47:1993;243-251.
13. Kimmel C.A., Cuff J.M., Kimmel G.L., Heredia D.J., Tudor N., Silverman P.M., Chen J. Skeletal development following heat exposure in the rat. Teratology. 47:1993;229-242.
14. Cuff J.M., Kimmel G.L., Kimmel C.A., Heredia D.J., Tudor N., Chen J. Relationship between abnormal somite development and axial skeletal defects in rats following heat exposure. Teratology. 48:1993;259-266.
15. Arora K.L., Cohen B.J., Beaudoin A.R. Fetal and placental responses to artificially induced hyperthermia in rats. Teratology. 19:1979;251-260.
16. Germain M.A., Webster W.S., Edwards M.J. Hyperthermia as a teratogen Parameters determining hyperthermia-induced head defects in the rat . Teratology. 31:1985;265-272.
17. Walsh D.A., Li K., Speirs J., Crowther C.E., Edwards M.J. Regulation of the inducible heat shock 71 genes in early neural development of cultured rat embryos. Teratology. 40:1989;321-334.
18. Walsh D.A., Zhe L., Zeng F., Yan W., Edwards M.E. Heat shock genes and cell cycle regulation during early mammalian development. Environ Med. 38:1994;1-6.
19. Jacks T., Weinberg R.A. Cell-cycle control and its watchman. Nature. 381:1996;643-644.
20. Elledge S.J. Cell cycle checkpoints Preventing an identity crisis . Science. 274:1996;1664-1672.
21. Wubah J.A., Ibrahim M.M., Gao X., Nguyen D., Pisano M.M., Knudsen T.B. Teratogen-induced eye defects mediated by p53-dependent apoptosis. Current Biology. 6:1996;60-69.
22. Fisher B.R., Heredia D.J., Brown K.M. Induction of hsp72 in heat-treated rat embryos A tissue-specific response . Teratology. 52:1995;90-100.
23. Primmett D.R.N., Stern C.D., Keynes R.J. Heat shock causes repeated segmental anomalies in the chick embryo. Development. 104:1988;331-339.
24. Primmett D.R.N., Norris W.E., Carlson G.J., Keynes R.J., Stern C.D. Periodic segmental anomalies induced by heat shock in the chick embryo are associated with the cell cycle. Development. 105:1989;119-130.
25. Burgess R, Rawls A, Brown D, Bradley A, Olson EN. Requirement of the paraxis gene for somite formation and musculoskeletal patterning Nature. 1996;384:570-3.