Functional and spectroscopic studies of a familial hypertrophic cardiomyopathy mutation in Motif X of cardiac myosin binding protein-C

European Biophysics Journal

Volumn 31, Issue 5, 2002, Pages 400-408

  Brown, Louise J ^a,b   Singh, Leena ^a,b   Sale, Kenneth L ^b,c   Yu, Bing ^a,b   Trent, Ronald ^a,b   Fajer, Peter G ^b,c   Hambly, Brett D ^a,b  

^a UNIVERSITY OF SYDNEY   (Australia)

^b ROYAL PRINCE ALFRED HOSPITAL   (Australia)

^c FLORIDA STATE UNIVERSITY   (United States)

Author keywords

Cardiac muscle; Familial hypertrophic cardiomyopathy; Myosin binding protein C

Indexed keywords

COMPLEMENTARY DNA; CONNECTIN; IMMUNOGLOBULIN; MYOSIN; MYOSIN BINDING PROTEIN C; CARRIER PROTEIN; MYOSIN-BINDING PROTEIN C;

ANIMAL CELL; ARTICLE; AUTOSOMAL DOMINANT DISORDER; CARBOXY TERMINAL SEQUENCE; CIRCULAR DICHROISM; CONTROLLED STUDY; DENATURATION; HUMAN; HUMAN CELL; HYPERTROPHIC CARDIOMYOPATHY; IMMUNOGLOBULIN STRUCTURE; MOLECULAR MODEL; MUTATION; NONHUMAN; PROTEIN BINDING; PROTEIN MOTIF; THERMODYNAMICS; ANIMAL; CATTLE; CELL CULTURE; CHEMICAL STRUCTURE; CHEMISTRY; COMPARATIVE STUDY; FAMILIAL HYPERTROPHIC CARDIOMYOPATHY; GENETICS; HEART MUSCLE CELL; METABOLISM; METHODOLOGY; PROTEIN DENATURATION; SENSITIVITY AND SPECIFICITY; SITE DIRECTED MUTAGENESIS; SPECTROSCOPY; STRUCTURE ACTIVITY RELATION; TEMPERATURE;

ANIMALIA; BACTERIA (MICROORGANISMS);

AMINO ACID MOTIFS; ANIMALS; CARDIOMYOPATHY, HYPERTROPHIC, FAMILIAL; CARRIER PROTEINS; CATTLE; CELLS, CULTURED; CIRCULAR DICHROISM; HUMANS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; MUTATION; MYOCYTES, CARDIAC; MYOSINS; PROTEIN BINDING; PROTEIN DENATURATION; SENSITIVITY AND SPECIFICITY; SPECTRUM ANALYSIS; STRUCTURE-ACTIVITY RELATIONSHIP; TEMPERATURE;

EID: 0036736331     PISSN: 01757571     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00249-002-0236-0     Document Type: Article

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