The interface between MyBP-C and myosin: Site-directed mutagenesis of the CX myosin-binding domain of MyBP-C

Journal of Muscle Research and Cell Motility

Volumn 20, Issue 7, 1999, Pages 703-716

  Miyamoto, C A ^a,b   Fischman, D A ^b   Reinach, F C ^a,b  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; ARGININE; ASPARTIC ACID; BINDING PROTEIN; CHYMOTRYPSIN; FIBRONECTIN; GLUTAMIC ACID; IMMUNOGLOBULIN; MEROMYOSIN; METHIONINE; MYOSIN; MYOSIN BINDING PROTEIN C; RECOMBINANT PROTEIN;

ARTICLE; ASSAY; BINDING AFFINITY; BINDING SITE; MODEL; MUTANT; MYOFILAMENT; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN POLYMERIZATION; SITE DIRECTED MUTAGENESIS; SKELETAL MUSCLE; VERTEBRATE;

VERTEBRATA;

EID: 0033382808     PISSN: 01424319     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1005513312939     Document Type: Article

References (43)

1. Alyonycheva TN, Mikawu T, Reinach FC and Fischman DA (1997) Isoform-specific interaction of the myosin-binding proteins (MyBPs) with skeletal and cardiac myosin is a property of the C-terminal immunoglobulin domain. J Biol Chem 272: 20866-20872.
2. Atkinson SJ and Stewart M (1992) Molecular interactions in myosin assembly: role of the 28-residue charge repeat in the rod. J Mol Biol 226: 7-13.
3. Bennett P, Starr R, Elliott A and Offer G (1985) The structure of C-protein and X-protein molecules and a polymer of X-protein. J Mol Biol 184: 297-309.
4. Bonné G, Carrier L, Bercovici J, Cruaud C, Richard P, Hainque B, Gautel M, Labeit S, James M, Beckmann J, Weissenbach J, Vosberg H-P, Fiszman M, Komajda M and Schwartz K (1995) Cardiac myosin binding protein-C gene splice acceptor site mutation is associated with familial hypertrophic cardiomyopathy. Nature Genet 11: 438-440.
5. Carrier L, Bonné G, Bahrend E, Yu B, Richard P, Niel F, Hainque B, Cruaud C, Gary F, Labeit S, Bouhour JB, Duhourg O, Desnos M, Hagege AA, Trent RJ, Komajda M, Fiszman M and Schwartz K (1997) Organization and sequence of human cardiac myosin binding protein C gene (MYBPC3) and identification of mutations predicted to produce truncated proteins in familial hypertrophic cardiomyopathy. Circ Res 80: 427-434.
6. Craig R and Offer G (1976) The location of C-protein from rabbit skeletal muscle. Proc R Soc Lond B Biol Sci 192: 451-461.
7. Davis JS (1988) Interaction of C-protein with pH 8.0 synthetic thick filaments prepared from myosin of vertebrate skeletal muscle. J Muscle Res Cell Motil 9: 174-183.
8. Dennis J, Shimizu T, Reinach FC and Fischman DA (1984) Localization of C-protein isoforms in chicken skeletal muscle: ultrastructural detection using monoclonal antibodies. J Cell Biol 98: 1514-1522.
9. Einheber S and Fischman DA (1990) Isolation and characterization of a cDNA clone encoding avian skeletal muscle C-protein: An intracellular member of the immunoglobulin superfamily. Proc Natl Acad Sci USA 87: 2157-2161.
10. Freiburg A and Gautel M (1996) A molecular map of the interactions between titin and myosin-binding protein C. Implications for sarcomeric assembly in familial hypertrophic cardiomyopathy. Eur J Biochem 235: 317-323.
11. Fürst DO, Vinkemeier U and Weber K (1992) Mammalian skeletal muscle C-protein: purification from bovine muscle, binding to titin and the characterization of a full-length human cDNA. J Cell Sci 102: 769-778.
12. Gilbert R, Cohen JA, Pardo S, Basu A and Fischman DA (1999) Identification of the A-band localization domain of myosin binding proteins C and H (MyBP-C, MyBP-H) in skeletal muscle. J Cell Sci 112: 69-79.
13. Gilbert R, Kelly MG, Mikawa T and Fischman DA (1996) The carboxyl terminus of myosin binding protein C (MyBP-C, C-protein) specifies incorporation into the A-band of striated muscle. J Cell Sci 109: 101-111.
14. Gruen M and Gautel M (1999) Mutations in β-myosin S2 that cause familial hypertrophic cardiomyopathy (FHC) abolish the interaction with the regulatory domain of myosin-binding protein-C. J Mol Biol 286: 933-949.
15. Hartree EF (1972) Determination of protein: a modification of Lowry method that gives a linear photometric response. Anal Biochem 48: 422-427.
16. Holden HM, Ito M, Hartshorne DJ and Rayment I (1992) X-ray structure determination of telokin, the C-terminal domain of myosin light chain kinase, at 2.8 Å resolution. J Mol Biol 227: 840-851.
17. Josephs R and Harrington WF (1996) Studies on the formation and physical chemical properties of synthetic myosin filaments. Biochemistry 5: 3474-3487.
18. Kaminer B and Bell AL (1966) Myosin filamentogenesis: effects of pH and ionic concentration. J Mol Biol 20: 391-401.
19. Koretz JF (1979) Effects of C-protein on synthetic myosin filament structure. Biophys J 27: 433-446.
20. Korelz JF, Irving TC and Wang K (1993) Filamentous aggregates of native titin and binding of C-protein and AMP-deaminase. Arch Biochem Biophys 304: 305-309.
21. Koshida S, Kurasawa M, Yasuda M, Sato N and Obinata T (1995) Assembly of cardiac C-protein during myofibrillogenesis in myogenic cells in culture. Cell Struct Funct 20: 253-261.
22. Kunkel TA, Roberts JD and Zakour RA (1987) Rapid and efficient site-specific mutugenesis without phenotypic selection. Meth Enzymol 154: 367-382.
23. Lakowicz JR (1983) Principles of Fluorescence Spectroscopy. Plenun Press, New York.
24. Lin Z, Lu M, Schultheiss T, Choi J, Holtzer S, Dilullo C, Fischman DA and Holtzer H (1994) Sequential appearance of muscle-specific proteins in myoblasts as a function of time after cell division: Evidence for a conserved myoblast differentiation program in skeletal muscle. Cell Motil 29: 1-19.
25. McLachlan AD and Karn J (1982) Periodic charge distributions in the myosin rod amino acid sequence match crossbridgc spacings in muscle. Nature 299: 226-231.
26. McLachlan AD and Karn J (1983) Periodic features of the amino acid sequence of nematode myosin rod. J Mol Biol 164: 605-626.
27. Miyahara M and Noda H (1980) Interaction of C-protein with myosin. J Biochem 87: 1413-1420.
28. Moos C (1981) Fluorescence microscope study of binding of added C-protein to skeletal muscle myofibrils. J Cell Biol 90: 25-31.
29. Moos C, Offer G, Starr R and Bennett P (1975) Interaction of C-protein with myosin, myosin rod and light meromyosin. J Mol Biol 97: 1-9.
30. Moos C, Mason C, Besterman J, Feng I and Dublin J (1978) The binding of skeletal muscle C-protein to F-actin, and its relation to the interaction of actin with myosin subfragment. J Mol Biol 124: 571-586.
31. Obinata T, Reinach FC, Bader DM, Masaki T, Kitani S and Fischman DA (1984) Immunochemical analysis of C-protein isoform transitions during the development of chicken skeletal muscle. Dev Biol 101: 116-124.
32. Offer G, Moos C and Starr R (1973) A new protein of thick filaments of vertebrate skeletal myofibrils. J Mol Biol 74: 653-676.
33. Okagaki T, Weber FE, Fischman DA, Vaughan KT, Mikawa T and Reinach FC (1993) The major myosin-binding domain of skeletal MyBP-C (C-protein) residues in the COOH-terminal, immunoglobulin C2 motif. J Cell Biol 123: 619-626.
34. Provencher SW and Glöckner J (1981) Estimation of globular protein secondary structure from circular dichroism. Biochemistry 20: 33-37.
35. Rottbauer W, Gautel M, Zehelein J, Labeit S, Franz WM, Fischer C, Vollrath B, Mall G, Dietz R, Kübler W and Katus HA (1997) Novel splice donor site mutation in the cardiac myosin-binding protein-C gene in familial hypertrophic cardiomyopathy. Characterization of cardiac transcript and protein. J Clin Invest 100: 475-482.
36. Sanger F, Nicklen S and Coulson AR (1977) DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci USA 74: 5463-5467.
37. Seiler HS, Fischman DA and Leinwand LA (1996) Modulation of myosin filament organization by C-protein family members. Mol Biol Cell 7: 113-127.
38. Starr R and Offer G (1971) Polypeptide chain of intermediate molecular weight in myosin preparations. FEBS Lett 15: 40-44.
39. Starr R and Offer G (1978) The interaction of C-protein with heavy meromyosin and subfragment-2. Biochem J 171: 813-816.
40. Studier FW, Rosenberg AH, Dunn JJ and Dubendorff JW (1990) Use of T7 RNA polymerase to direct expression of cloned genes. Meth Enzymol 185: 60-89.
41. Watkins H, Conner D, Thierfelder L, Jarcho JA, Macrae C, McKenna WJ, Maron BJ, Seidman JG and Seidman CE (1995) Mutations in the cardiac myosin binding protein-C gene on chromosome II cause familial hypertrophic cardiomyopathy. Nature Genet II: 434-437.
42. Yamamoto K (1986) The binding of skeletal muscle C-protein to regulated actin. FEBS Lett 208: 123-127.
43. Yasuda M, Koshida S, Sato N and Obinata T (1995) Complete primary structure of chicken cardiac C-protein (MyBP-C) and its expression in developing striated muscles. J Mol Cell Cardiol 27: 2275-2286.