Estrogen dependence of synthesis and secretion of apolipoprotein B- containing lipoproteins in the chicken hepatoma cell line, LMH-2A

Journal of Lipid Research

Volumn 38, Issue 7, 1997, Pages 1308-1317

  Hermann, Marcela ^a   Seif, Fridolin ^a   Schneider, Wolfgang J ^a   Ivessa, N Erwin ^a  

^a University and Biocenter Vienna ^*  (Austria)

Author keywords

Apolipoprotein II; Hormonal regulation; Secretory pathway; Very low density lipoprotein

Indexed keywords

APOLIPOPROTEIN B; ESTROGEN; ESTROGEN RECEPTOR; LIPOPROTEIN; MOXESTROL; VERY LOW DENSITY LIPOPROTEIN; VITELLOGENIN;

ANIMAL CELL; ARTICLE; CHICKEN; CONTROLLED STUDY; HEPATOMA CELL; LIPOPROTEIN SECRETION; LIPOPROTEIN SYNTHESIS; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; APOLIPOPROTEINS; APOLIPOPROTEINS B; CHICKENS; ESTRADIOL CONGENERS; ESTROGENS; ETHINYL ESTRADIOL; FEMALE; IMMUNOSORBENT TECHNIQUES; KINETICS; LIPOPROTEINS, VLDL; LIVER NEOPLASMS, EXPERIMENTAL; PROTEIN PRECURSORS; TUMOR CELLS, CULTURED; VITELLOGENINS;

EID: 0030878768     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. Havel, R. J., and J. P. Kane. 1995. Introduction: Structure and metabolism of plasma lipoproteins. In The Metabolic and Molecular Bases of Inherited Disease. C. R. Scriver, A. L. Beaudet, W. S. Sly, and D. Valle, editors. McGraw-Hill, New York, NY. Vol. 2. 1841-1851.
2. Schneider, W. J., R. Carroll, D. L. Severson, and J. Nimpf. 1990. Apolipoprotein VLDL-II inhibits lipolysis of triglyceride-rich lipoproteins in the laying hen. J. Lipid Res. 31: 507-513.
3. Cartwright, I. J., A. M. Hebacchi, and J. A. Higgins. 1993. Transit and sorting of apolipoprotein B within the endoplasmic reticulum and Golgi compartments of isolated hepatocytes from normal and orotic acid-fed rats. J. Biol. Chem. 268: 20937-20952.
4. Borén, J., L. Graham, M. Wettesten, J. Scott, A. White, and S-O. Olofsson. 1992. The assembly and secretion of apoB-100-containing lipoproteins in HepG2 cells. ApoB is cotranslationally integrated into lipoproteins. J. Biol. Chem. 267: 9858-9867.
5. Furukawa, S., N. Sakata, H. N. Ginsberg, and J. L. Dixon. 1992. Studies of the sites of intracellular degradation of apolipoprotein B in HepG2 cells. J. Biol. Chem. 267: 22630-22638.
6. While, A. L., D. L. Graham, J. LeGros, R. J. Pease, and J. Scott. 1992. Oleate-mediated stimulation of apolipoprotein B secretion from rat hepatoma cells. A function of the ability of apolipoprotein B to direct lipoprotein assembly and escape presecretory degradation. J. Biol. Chem. 267: 15657-15664.
7. McLeod, R. S., Y. Wang, S. Wang, A. Rusiñol, P. Links, and Z. Yao. 1996. Apolipoprotein B sequence requirements for hepatic very low density lipoprotein assembly. Evidence that hydrophobic sequences within apolipoprotein B48 mediate lipid recruitment. J. Biol. Chem. 271: 18445-18455.
8. Bamberger, M. J., and M. D. Lane. 1990. Possible role of the Golgi apparatus in the assembly of very low density lipoprotein. Proc. Natl. Acad. Sci. USA. 87: 2390-2394.
9. Dixon, J. L., R. Chattapadhyay, T. Huima, C. M. Redman, and D. Banerjee. 1992. Biosynthesis of lipoprotein: location of nascent apoAI and apoB in the rough endoplasmic reticulum of chicken hepatocytes. J. Cell Biol. 117: 1161-1169.
10. Yao, Z., and R. McLeod. 1994. Synthesis and secretion of hepatic apolipoprotein B-containing lipoproteins. Biochim. Biophys. Acta. 1212: 152-166.
11. Pease, R. J., and J. M. Leiper. 1996. Regulation of hepatic apolipoprotein-B-containing lipoprotein secretion. Curr. Opin. Lipidol. 7: 132-138.
12. Evans, M. I., R. Silva, and J. B. Burch. 1988. Isolation of chicken vitellogenin I and III cDNAs and the developmental regulation of five estrogen-responsive genes in the embryonic liver. Genes Dev. 2: 116-124.
13. Kirchgessner, T. G., C. Heinzmann, K. L. Svenson, D. A. Gordon, M. Nicosia, H. G. Lebherz, A. J. Lusis, and D. L. Williams. 1987. Regulation of chicken apolipoprotein B: cloning, tissue distribution, and estrogen induction of mRNA. Gene. 59: 241-251.
14. Burch, J. B. 1984. Identification and sequence analysis of the 5′ end of the major chicken vitellogenin gene. Nucleic Acids Res. 12: 1117-1135.
15. Wijnholds, J., J. N. Philipsen, and G. Ab. 1988. Tissue-specific and steroid-dependent interaction of transcription factors with the oestrogen-inducible apoVLDL II promoter in vivo. EMBO J. 7: 2757-2763.
16. Kawaguchi, T., K. Nomura, Y. Hirayama, and T. Kitagawa. 1987. Establishment and characterization of a chicken hepatocellular carcinoma cell line, LMH. Cancer Res. 47: 4460-4464.
17. Binder, R., C. C. MacDonald, J. B. E. Burch, C. B. Lazier, and D. L. Williams. 1990. Expression of endogenous and transfected apolipoprotein II and vitellogenin II genes in an estrogen responsive chicken liver cell line. Mol. Endocrinol. 4: 201-208.
18. Berkowitz, E. A., and M. I. Evans. 1992. Estrogen-dependent expression of the chicken very low density apolipoprotein II gene in serum-free cultures of LMH cells. In Vitro Cell Dev. Biol. 28A: 391-396.
19. Berkowitz, E. A., and M. I. Evans. 1992. Functional analysis of regulatory regions upstream and in the first intron of the estrogen-responsive chicken very low density apolipoprotein II gene. J. Biol. Chem. 267: 7134-7138.
20. Sensel, M. G., R. Binder, C. B. Lazier, and D. L. Williams. 1994. Reactivation of apolipoprotein II gene transcription by cycloheximide reveals two steps in the deactivation of estrogen receptor-mediated transcription. Mol. Cell. Biol. 14: 1733-1742.
21. Nimpf, J., R. George, and W. J. Schneider. 1988. Apolipoprotein specificity of the chicken receptor for low and very low density lipoproteins: lack of recognition of apolipoprotein VLDL-II. J. Lipid Res. 29: 657-667.
22. Stifani, S., R. George, and W. J. Schneider. 1988. Solubilization and characterization of the chicken oocyte vitellogenin receptor. Biochem. J. 250: 467-475.
23. Harlow, E., and D. Lane. 1988. Antibodies: A Laboratory Manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY. 310.
24. Laemmli, U. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 227: 680-685.
25. Lowry, O. H., N. J. Rosebrough, A. L. Farr, and R. J. Randall. 1951. Protein measurement with Folin phenol reagent. J. Biol. Chem. 193: 265-275.
26. Schneider, W. J., J. L. Goldstein, and M. S. Brown. 1980. Partial purification and characterization of the low density lipoprotein receptor from bovine adrenal cortex. J. Biol. Chem. 255: 11442-11447.
27. Chan, L., R. L. Jackson, B. W. O'Malley, and A. R. Means. 1976. Synthesis of very low density lipoproteins in the cockerel. Effects of estrogen. J. Clin. Invest. 58: 368-379.
28. Codina-Salada, J., J. P. Moore, and L. Chan. 1983. Kinetics of primary and secondary stimulation of the mRNA for APOVLDL-II, a major yolk protein, in the cockerel liver by estrogen. Endocrinology. 113: 1158-1160.
29. Tam, S. P., T. K. Archer, and R. G. Deeley. 1986. Biphasic effects of estrogen on apolipoprotein synthesis in human hepatoma cells: mechanism of antagonism by testosterone. Proc. Natl. Acad. Sci. USA. 83: 3111-3115.
30. van het Schip, F., R. Strijker, J. Samallo, M. Gruber, and A. B. Geert. 1986. Conserved sequence motifs upstream from the co-ordinately expressed vitellogenin and apoVLDLII genes of chicken. Nucleic Acids Res. 14: 8669-8680.
31. Thrift, R. N., J. Drisko, S. Dueland, J. D. Trawick, and R. A. Davis. 1992. Translocation of apolipoprotein B across the endoplasmic reticulum is blocked in a nonhepatic cell line. Proc. Natl. Acad. Sci. USA. 89: 9161-9165.
32. Kaptein, A., E. C. M. de Wit, and H. M. G. Princen. 1994. Butyrate stimulates the secretion of apolipoprotein B-100-containing lipoproteins from HepG2 cells by inhibiting the intracellular degradation. Biochim. Biophys. Acta. 1213: 349-356.
33. Dixon, J. L., S. Furukawa, and H. N. Ginsberg. 1991. Oleate stimulates secretion of apolipoprotein B-containing lipoproteins from HepGS cells by inhibiting early intracellular degradation of apolipoprotein B. J. Biol. Chem. 266: 5080-5086.
34. Dashti, N., P. Alaupovic, C. Knight-Gibson, and E. Koren. 1987. Identification and partial characterization of discrete apolipoprotein B-containing lipoprotein particles produced by human hepatoma cell line HepG2. Biochemistry. 26: 4837-4846.
35. Kudzma, D. J., J. B. Swaney, and E. N. Ellis. 1979. Effects of estrogen administration on the lipoproteins and apoproteins of the chicken. Biochim. Biophys. Acta. 572: 257-268.
36. Hermier, D., P. Forgez, J. Williams, and M. J. Chapman. 1989. Alterations in plasma lipoproteins and apolipoproteins associated with estrogen-induced hyperlipidemia in the laying hen. Eur. J. Biochem. 184: 109-118.
37. Boström, K., J. Borén, M. Wettesten, A. Sjöberg, G. Bondjers, O. Wiklund, P. Carlsson, and S-O. Olofsson. 1988. Studies on the assembly of apoB-100-containing lipoproteins in HepG2 cells. J. Biol. Chem. 263: 4434-4442.
38. Bamberger, M. J., and M. D. Lane. 1988. Assembly of very low density lipoprotein in the hepatocyte. Differential transport of apoproteins through the secretory pathway. J. Biol. Chem. 263: 11868-11878.