Distal ureter morphogenesis depends on epithelial cell remodeling mediated by vitamin A and Ret

Nature Genetics

Volumn 32, Issue 1, 2002, Pages 109-115

  Batourina, Ekatherina ^a   Choi, Christopher ^a   Paragas, Neal ^a   Bello, Natalie ^a   Hensle, Terry ^a   Costantini, Frank D ^a   Schuchardt, Anita ^a   Bacallao, Robert L ^a   Mendelsohn, Cathy L ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN RET; RETINOIC ACID; RETINOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLADDER; CONTROLLED STUDY; EMBRYONIC STRUCTURES; EPITHELIUM CELL; GENE MUTATION; HYDRONEPHROSIS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; KIDNEY HYPOPLASIA; KNOCKOUT MOUSE; MEGAURETER; MORPHOGENESIS; MOUSE; NONHUMAN; ORGAN CULTURE; PLEIOTROPY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTO ONCOGENE; RETINOL DEFICIENCY; SIGNAL TRANSDUCTION; TRANSGENE; TRANSGENIC MOUSE; URETER; UROGENITAL TRACT MALFORMATION;

ANIMALS; DROSOPHILA PROTEINS; EPITHELIAL CELLS; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MORPHOGENESIS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-RET; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTORS, RETINOIC ACID; SIGNAL TRANSDUCTION; URETER; URINARY BLADDER; VITAMIN A;

ANIMALIA; INSERTION SEQUENCES; MUS MUSCULUS; WOLFFIA;

EID: 0036730119     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/ng952     Document Type: Article

References (40)

1. Fetal ureteric reflux
2. Antenatal diagnosis of congenital abnormalities in the urinary tract. Results from the Northern Region Fetal Abnormality Survey
3. An analysis of the syndrome of malformations induced by maternal vitamin A deficiency. Effects of restoration of vitamin A at various times during gestation
4. Nonsteroid nuclear receptors: What are genetic studies telling us about their role in real life?
5. Genetic analysis of the retinoid signal
6. Function of vitamin A in vertebrate embryonic development
7. Malformations in the genito-urinary tract induced by maternal vitamin A deficiency in the rat
8. Function of the retinoic acid receptors (RARs) during development (11). Multiple abnormalities at various stages of organogenesis in RAR double mutants
9. Vitamin A controls epithelial/mesenchymal interactions through Ret expression
10. Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret
11. Renal agenesis and hypodysplasia in ret-k- mutant mice result from defects in ureteric bud development
12. Expression of green fluorescent protein in the ureteric bud of transgenic mice: A new tool for the analysis of ureteric bud morphogenesis
13. The terminal part of the Wolffian duct
14. Normal and abnormal development of the ureter in the human embryo-a mechanistic consideration
15. Functional receptor for GDNF encoded by the c-ret proto-oncogene
16. Glial cell line-derived neurotrophic factor activates the receptor tyrosine kinase RET and promotes kidney morphogenesis
17. Glial-cell-line-derived neurotrophic factor is required for bud initiation from ureteric epithelium
18. GDNF-induced activation of the ret protein tyrosine kinase is mediated by GDNFR-α, a novel receptor for GDNF
19. Glial cell line-derived neurotrophic factor-dependent RET activation can be mediated by two different cell-surface accessory proteins
20. Characterization of a multicomponent receptor for GDNF
21. Stromal cells mediate retinoid-dependent functions essential for renal development
22. Renal agenesis and the absence of enteric neurons in mice lacking GDNF
23. Metanephros organogenesis is highly stimulated by vitamin A derivatives in organ culture
24. Retinoic acid receptors and cellular retinoid binding proteins. I. A systematic study of their differential pattern of transcription during mouse organogenesis
25. Embryonic retinoic acid synthesis is essential for early mouse post-implantation development
26. Dominant effects of RET receptor misexpression and ligand-independent RET signaling on ureteric bud development
27. Paradigm shift from classic anatomic theories to contemporary cell biological views of CAKUT
28. Duplex kidneys: A correlation of renal dysplasia with position of the ureteral orifice
29. How they begin and how they end: Classic and new theories for the development and deterioration of congenital anomalies of the kidney and urinary tract, CAKUT
30. Role of the angiotensin type 2 receptor gene in congenital anomalies of the kidney and urinary tract, CAKUT, of mice and men
31. Bone morphogenetic protein 4 regulates the budding site and elongation of the mouse ureter
32. Murine forkhead/winged helix genes Foxcl (Mfl) and Foxc2 (Mfh1) are required for the early organogenesis of the kidney and urinary tract
33. GDNF induces branching and increased cell proliferation in the ureter of the mouse
34. The RET-glial cell-derived neurotrophic factor (GDNF) pathway stimulates migration and chemoattraction of epithelial cells
35. Voxx: A PC-based, near real-time volume rendering system for biological microscopy