Human CD26 expression in transgenic mice affects murine T-cell populations and modifies their subset distribution

Human Immunology

Volumn 63, Issue 9, 2002, Pages 719-730

  Simeoni, Luca ^a   Rufini, Alessandro ^a   Moretti, Tiziana ^b   Forte, Pietro ^a   Aiuti, Alessandro ^c   Fantoni, Antonio ^a,b  

^a Sezione Di Genetica Molecolare   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c SAN RAFFAELE SCIENTIFIC INSTITUTE   (Italy)

Author keywords

CD26; Proliferation; T cell homeostasis; Thymus; Transgenic mice

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; DIPEPTIDYL PEPTIDASE IV;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN EXPRESSION; ARTICLE; CONTROLLED STUDY; HUMAN; IMMUNOREGULATION; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION; THYMUS; TRANSGENIC MOUSE;

AGING; ANIMALS; ANTIGENS, CD26; APOPTOSIS; CD4-CD8 RATIO; CELL DIFFERENTIATION; GENE EXPRESSION; HOMEOSTASIS; HUMANS; LYMPHOCYTE ACTIVATION; LYMPHOID TISSUE; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; MICE, TRANSGENIC; PHENOTYPE; SIGNAL TRANSDUCTION; T-LYMPHOCYTE SUBSETS;

EID: 0036729668     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0198-8859(02)00433-0     Document Type: Article

References (70)

1. CD26: A surface protease involved in T-cell activation
2. CD26/dipeptidyl peptidase IV in lymphocyte growth regulation
3. Structure of CD26 (dipeptidyl peptidase IV) and function in human T cell activation
4. The structure and function of CD26 in the T-cell immune response
5. Dipeptidyl-peptidase IV/CD26 on T cells: Analysis of an alternative T-cell activation pathway
6. CD26, let it cut or cut it down
7. Proline specific endo and exopeptidases
8. Molecular analyses of human and rat dipeptidyl peptidase IV
9. Regulation of the receptor specificity and function of the chemokine RANTES (regulated on activation, normal T cell-expressed and secreted) by dipeptidyl peptidase IV (CD26)-mediated cleavage
10. Amino-terminal truncation of chemokines by CD26/dipeptidyl-peptidase IV
11. Anti-HIV-1 and chemotactic activities of human stromal cell-derived factor 1 alfa (SDF-1 alfa) and SDF-1 beta are abolished by CD26/dipeptidyl peptidase IV-mediated cleavage
12. Functional comparison of two human monocyte chemotactic protein-2 isoforms, role of the amino-terminal pyroglutamic acid and processing by CD26/dipeptidyl peptidase IV
13. A novel T cell-activating molecule (THAM) highly expressed on CD4-CD8-murine thymocytes
14. 1F7 (CD26): A marker of thymic maturation involved in the differential regulation of the CD3 and CD2 pathways of human thymocytes activation
15. Evidence that thymocyte-activating molecule is mouse CD26 (dipeptidyl peptidase IV)
16. Thymocyte costimulating antigen is CD26 (dipeptidyl peptidase IV)
17. Cloning and functional expression of the T cell activation antigen CD26
18. Activation of cord T lymphocytes
19. cDNA cloning for mouse thymocyte-activating molecule. A multifunctional ecto-dipeptidyl peptidase IV (CD26) included in a subgroup of serene proteases
20. Correlation of the epitopes defined by anti-CD26 mAbs and CD26 function
21. CD26 induces T-cell proliferation by tyrosine protein phosphorylation
22. The cytoplasmic tail of the T cell receptor zeta chain is required for signaling via CD26
23. The T-cell receptor associated zeta-chain is required but not sufficient for CD26 (dipeptidyl peptidase IV) mediated signaling
24. Molecular analysis of CD26-mediated signal transduction in T cells
25. Coassociation of CD26 (dipeptidyl peptidase IV) with CD45 on the surface of human T lymphocytes
26. CD26-mediated signaling for T cell activation occurs in lipid rafts through its association with CD45RO
27. Direct association of adenosine deaminase with a T cell activation antigen, CD26
28. Binding of adenosine deaminase to the lymphocyte surface via CD26
29. Internalization of CD26 by mannose 6-phosphate/insulin-like growth factor II receptor contributes to T cell activation
30. Human thymocyte dipeptidyl peptidase IV (CD26) activity is altered with stage of ontogeny
31. Cytofluorografic evidence that thymocyte dipeptidyl peptidase IV (CD26) activity is altered with stage of ontogeny and apoptotic status
32. The structure of the human CD2 gene and its expression in transgenic mice
33. Human CD2 3′-flanking sequences confer high-level, T cell-specific, position-independent gene expression in transgenic mice
34. Human CD4 produced in lymphoid cells of transgenic mice binds HIV gp120 and modifies the subsets of mouse T-cell populations
35. Membrane expression of HLA-Cw4 free chains in activated T cells of transgenic mice
36. 1F7, a novel cell surface molecule, involved in helper function of CD4 cells
37. Human U937 cell surface peptidase activities: Characterization and degradative effect on tumor necrosis factor-α
38. Ta1 a novel 105 kD human T cell activation antigen defined by a monoclonal antibody
39. T-cell apoptosis detected in situ during positive and negative selection in the thymus
40. Evidence for the induction of apoptosis in thymocytes by 2,3,7,8-tetrachlorodibenzo-p-dioxin in vivo
41. Identical forms of the CD2 antigen expressed by mouse T and B lymphocytes
42. Effect of bovine growth hormone administration on the pattern of thymic involution in mice
43. Thymic involution with ageing: Obsolescence or good housekeeping?
44. Involution of the mammalian thymus, one of the leading regulators of aging
45. Control of thymus physiology by peptidic hormones and neuropeptides
46. Immunoregulatory role of neurotransmitters
47. Thymic aging in ICR female mice is suspended by prolonged hydrocortisone exposure
48. Thymic endocrinology
49. Hormone regulation of immune homeostasis: Local or long distance?
50. Homeostasis, thymic hormones and aging
51. The effect of age on mitogen responsive T cell precursors in human beings is completely restored by interleukin-2
52. Patterns of dual lymphocyte development in co-cultures of foetal thymus and lymphohaemopoietic cells from young and old mice
53. Heparin inhibition of autonomous growth implicates amphiregulin as an autocrine growth factor for normal human mammary epithelial cells
54. Thymic involution in aging. Prospects for correction
55. Effect of synthetic thymic humoral factor (THF-gamma 2) on T cell activities in immunodeficient ageing mice
56. Thymic endocrine activity in children with idiopathic growth-hormone deficiency
57. In vivo effects of growth hormone on thymus function in aging mice
58. Growth hormone and insulin-like growth factor-I stimulate hormonal function and proliferation of thymic epithelial cells
59. Growth hormone and its receptor are expressed in human thymic cells
60. Effects of growth hormone on thymocyte development from progenitor cells in the bone marrow
61. Repopulation of the atrophied thymus in diabetic rats by insulin-like growth factor I
62. Growth allometry of organs, muscles and bones in mice from lines divergently selected on the basis of plasma insulin-like growth factor-I
63. Recombinant human insulin-like growth factor binding protein-3 (rhIGFBP-3): Effects on the glycemic and growth promoting activities of rhIGF-1 in the rat
64. Dipeptidyl peptidase IV and trypsin-like enzymatic degradation of human growth hormone-releasing hormone in plasma
65. Kinetics of dipeptidyl peptidase IV proteolysis of growth hormone-releasing factor and analogs
66. Characterization of a growth hormone-releasing factor from a human pancreatic islet tumour
67. Neuroendocrine regulation of growth hormone
68. Interaction between the CD45 antigen and phytohemagglutinin. Inhibitory effect on the lectin-induced T cell proliferation by anti-CD45 monoclonal antibody
69. Molecular mechanisms underlying lymphocyte recirculation. II. Differential regulation of LFA-1 in the interaction between lymphocytes and high endothelial cells