Distinct in vivo requirements for establishment versus maintenance of transcriptional repression

Nature Genetics

Volumn 32, Issue 1, 2002, Pages 206-210

  Wheeler, John C ^a,b   VanderZwan, Christine ^a   Xu, Xiaoti ^a   Swantek, Deborah ^a   Tracey, W Daniel ^a   Gergen, J Peter ^a  

^a STONY BROOK UNIVERSITY   (United States)

^b Rothberg Institute for Childhood Diseases   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA;

ARTICLE; DROSOPHILA MELANOGASTER; EMBRYO; EMBRYO DEVELOPMENT; GENE REPRESSION; GENETIC TRANSCRIPTION; IN SITU HYBRIDIZATION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; TRANSCRIPTION REGULATION;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; DNA-BINDING PROTEINS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; FEMALE; GENE EXPRESSION REGULATION; GENE SILENCING; HISTONE DEACETYLASES; HOMEODOMAIN PROTEINS; MALE; NUCLEAR PROTEINS; REPRESSOR PROTEINS; TRANSCRIPTION FACTORS;

DROSOPHILA MELANOGASTER; EUKARYOTA; MELANOGASTER;

EID: 0036727514     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/ng942     Document Type: Article

References (23)

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3. Interaction of short-range repressors with Drosophila CtBP in the embryo
4. Drosophila C-terminal binding protein functions as a context-dependent transcriptional co-factor and interferes with both mad and groucho transcriptional repression
5. Groucho is required for Drosophila neurogenesis, segmentation, and sex determination and interacts directly with hairy-related bHLH proteins
6. The WRPW motif of the hairy-related basic helix-loop-helix repressor proteins acts as a 4-amino-acid transcription repression and protein-protein interaction domain
7. The Rpd 3 histone deacetylase is required for segmentation of the Drosophila embryo
8. The histone deacetylase RPD3 counteracts genomic silencing in Drosophila and yeast
9. Alternatively spliced transcripts of the Drosophila tramtrack gene encode zinc finger proteins with distinct DNA binding specificities
10. Ectopic expression of the Drosophila tramtrack gene results in multiple embryonic defects including repression of even-skipped and fushi-tarazu
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12. Direct activation of Sex-lethal transcription by the Drosophila runt protein
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14. Glial development in the Drosophila CNS requires concomitant activation of glial and repression of neuronal differentiation genes
15. The BTB domain, found primarily in zinc finger proteins, defines an evolutionarily conserved family that includes several developmentally regulated genes in Drosophila
16. A functional interaction between the histone deacetylase Rpd3 and the corepressor groucho in Drosophila development
17. Histone deacetylases: Silencers for hire
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20. Gap gene properties of the pair-rule gene runt during Drosophila segmentation
21. Concentration-dependent activities of the even-skipped protein in Drosophila embryos
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23. Regulation of runt transcription by Drosophila segmentation genes