Targeted mutation of Cyln2 in the Williams syndrome critical region links CLIP-115 haploinsufficiency to neurodevelopmental abnormalities in mice

Nature Genetics

Volumn 32, Issue 1, 2002, Pages 116-127

  Hoogenraad, Casper C ^a   Koekkoek, Bas ^a   Akhmanova, Anna ^a   Krugers, Harm ^b   Dortland, Bjorn ^a   Miedema, Marja ^a   van Alphen, Arjan ^a   Kistler, Werner M ^a   Jaegle, Martine ^a   Koutsourakis, Manoussos ^a   Van Camp, Nadja ^c   Verhoye, Marleen ^c   van der Linden, Annemie ^c   Kaverina, Irina ^d   Grosveld, Frank ^a   De Zeeuw, Chris I ^a   Galjart, Niels ^a  

^a ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

^c UNIVERSITY OF ANTWERP   (Belgium)

^d ERICH SCHMID INSTITUTE OF MATERIALS SCIENCE   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; DYNACTIN; PROTEIN; PROTEIN CLIP 115; PROTEIN CLIP 170; PROTEIN CYLN2; UNCLASSIFIED DRUG;

ALLELE; ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; CHROMOSOME 7Q; CONTROLLED STUDY; DELETION MUTANT; ELECTROPHYSIOLOGY; GENE ACTIVITY; GENE MUTATION; GENE TARGETING; GROWTH RETARDATION; HEMIZYGOSITY; HIPPOCAMPUS; MICROTUBULE; MOTOR COORDINATION; MOUSE; NERVE CELL DIFFERENTIATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; PROTEIN ANALYSIS; RNA ANALYSIS; WILLIAMS BEUREN SYNDROME;

ANIMALS; BRAIN; DYNEIN ATPASE; GENE TARGETING; HETEROZYGOTE; MICE; MICE, KNOCKOUT; MICROTUBULE-ASSOCIATED PROTEINS; MOTOR ACTIVITY; MUTAGENESIS, SITE-DIRECTED; NEOPLASM PROTEINS; NERVE TISSUE PROTEINS; PHENOTYPE; WILLIAMS SYNDROME;

ANIMALIA;

EID: 0036724985     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/ng954     Document Type: Article

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