Enhanced thromboxane synthesis during chronic reductions in uterine perfusion pressure in pregnant rats

American Journal of Hypertension

Volumn 15, Issue 9, 2002, Pages 793-797

  Llinás, Maria T ^a   Alexander, Barbara T ^a   Seedek, Mona ^a   Abram, Sean R ^a   Crell, Anna ^a   Granger, Joey P ^a,b  

^a UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MISSISSIPPI MEDICAL CENTER   (United States)

Author keywords

Hypertension; Preeclampsia; Pregnancy; Thromboxane

Indexed keywords

7 [3 [(4 PHENYLSEMICARBAZIDO)METHYL] 7 OXABICYCLO[2.2.1]HEPT 2 YL] 5 HEPTENOIC ACID; THROMBOXANE A2; HYDRAZINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE REGULATION; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; GLOMERULUS FILTRATION RATE; INTRAUTERINE PRESSURE; KIDNEY VEIN; MATERNAL HYPERTENSION; MEAN ARTERIAL PRESSURE; NONHUMAN; PATHOGENESIS; PREGNANCY; PRIORITY JOURNAL; RAT; TISSUE PERFUSION; URINE LEVEL; VASOCONSTRICTION; ANIMAL; BIOSYNTHESIS; DISEASE MODEL; DRUG ANTAGONISM; DRUG EFFECT; HYPERTENSION; KIDNEY CIRCULATION; PATHOPHYSIOLOGY; PHYSIOLOGY; PREECLAMPSIA; PREGNANCY COMPLICATION; UTERUS; VASCULARIZATION;

ANIMALS; DISEASE MODELS, ANIMAL; FEMALE; HYDRAZINES; HYPERTENSION; PRE-ECLAMPSIA; PREGNANCY; PREGNANCY COMPLICATIONS, CARDIOVASCULAR; RATS; RENAL CIRCULATION; THROMBOXANE A2; UTERUS;

EID: 0036724898     PISSN: 08957061     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0895-7061(02)02975-8     Document Type: Article

References (29)

1. Pathogenesis and genetics of pre-eclampsia
2. Clinical and biochemical evidence of endothelial cell dysfunction in the pregnancy syndrome preeclampsia
3. Pre-eclampsia: An endothelial cell disorder
4. Control of vascular resistance in the maternal and feto-placental arterial beds
5. Vascular function in preeclampsia
6. Renal and cardiovascular alterations
7. Peripheral arterial vasodilation hypothesis of sodium and water retention in pregnancy: Implications for pathogenesis of preeclampsia-eclampsia
8. Plasma and urinary endothelin 1, prostacyclin metabolites and platelet consumption in pre-eclampsia and essential hypertensive pregnancy
9. 2 and prostacyclin in plasma
10. Renal prostacyclin and thromboxane in normotensive and preeclamptic pregnant women and their infants
11. Low dose aspirin to prevent preeclampsia in women at high risk
12. CLASP: A randomised trial of low-dose aspirin for the prevention and treatment of pre-eclampsia among 9364 pregnant women
13. Low-dose aspirin therapy to prevent pre-eclampsia
14. Reduced uterine perfusion pressure during pregnancy in the rat is associated with increases in arterial pressure and changes in renal nitric oxide
15. Decreased endothelium-dependent vascular relaxation during reduction of uterine perfusion pressure in pregnant rat
16. Importance of prostaglandins in hypertension during reduced uteroplacental perfusion pressure
17. Renal function in rats with angiotensin II-salt induced hypertension: Effect of thromboxane synthesis inhibition and receptor blockade
18. Thromboxane synthesis and blood pressure in spontaneously hypertensive rats
19. Endothelin-A receptor blockade attenuates the hypertension in response to chronic reductions in uterine perfusion pressure
20. 2 in health and disease
21. Reduced sensitivity of the renal circulation to angiotensin II in pregnant rats
22. Effects of administered thromboxanes on the intact, normal rat kidney
23. 2 analog in late-pregnant rats
24. Vasoactive substances in the circulation of the pregnant dog during acute fetal ischemia
25. Irreversible uterine and renal changes induced by placental ischemia (rabbit)
26. Effect of endothelin-1 on human platelet shape change: Reversal of activation by naftidrofuryl
27. 2
28. Prevention of pre-eclampsia: Status and perspectives 2000
29. Preeclampsia prevention: Lessons from the low-dose aspirin therapy trials