Fe2+-tetracycline-mediated cleavage of the Tn10 tetracycline efflux protein TetA reveals a substrate binding site near glutamine 225 in transmembrane helix 7

Journal of Bacteriology

Volumn 184, Issue 18, 2002, Pages 5113-5120

  McMurry, Laura M ^a   Aldema Ramos, Mila L ^a   Levy, Stuart B ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDE; CARBON; CARRIER PROTEIN; COBALT; DIVALENT CATION; FERROUS ION; GLUTAMINE; GLYCYLCYCLINE DERIVATIVE; MAGNESIUM ION; PROTEIN TETA; TETRACYCLINE; TETRACYCLINE DERIVATIVE; UNCLASSIFIED DRUG;

ALPHA HELIX; ANTIBIOTIC RESISTANCE; ARTICLE; BINDING SITE; CATION EXCHANGE; CHELATION; CHEMICAL BOND; CONTROLLED STUDY; DRUG TRANSPORT; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DNA BINDING; PROTEIN FAMILY; PROTON TRANSPORT;

AMINO ACID SEQUENCE; ANTI-BACTERIAL AGENTS; ANTIPORTERS; BACTERIAL PROTEINS; BINDING SITES; BINDING, COMPETITIVE; BIOLOGICAL TRANSPORT; DNA TRANSPOSABLE ELEMENTS; ESCHERICHIA COLI; FERROUS COMPOUNDS; GLUTAMINE; IMMUNOBLOTTING; MOLECULAR SEQUENCE DATA; MUTATION; SUBSTRATE SPECIFICITY; TETRACYCLINE;

BACTERIA (MICROORGANISMS);

EID: 0036724715     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.184.18.5113-5120.2002     Document Type: Article

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