Comparable effects of DIGIBIND and DigiFab in thirteen digoxin immunoassays

Clinical Chemistry

Volumn 48, Issue 9, 2002, Pages 1580-1584

  McMillin, Gwendolyn A ^a   Owen, William E ^a   Lambert, Thomas L ^a   De, Barun K ^a   Frank, Elizabeth L ^a   Bach, Phillip R ^a   Annesley, Thomas M ^a   Roberts, William L ^a  

^a ARUP LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIGOXIN;

ARTICLE; IMMUNOASSAY; INTERMETHOD COMPARISON; KIDNEY FUNCTION; LABORATORY TEST; MONITORING; ULTRAFILTRATION;

EID: 0036721093     PISSN: 00099147     EISSN: None     Source Type: Journal    
DOI: 10.1093/clinchem/48.9.1580     Document Type: Article

References (19)

1. Digoxin and its related endogenous factors
2. Recognition and management of digitalis intoxication
3. Review of clinical experience with digoxin immune Fab (ovine)
4. The use of antibodies in clinical cardiology
5. Digitalis toxicity: Using immunotherapy when supportive care isn't enough
6. Pharmacokinetics of digoxin-specific Fab: Effects of decreased renal function and age
7. Determination of free digoxin concentrations in serum for monitoring Fab treatment of digoxin overdose
8. Validity of unbound digoxin measurements by immunoassays in presence of antidote (Digibind)
9. Digoxin measurements following plasma ultrafiltration in two patients with digoxin toxicity treated with specific Fab fragments
10. Effect of therapeutic digoxin antibodies on digoxin assays
11. Effects of digoxin immune Fab (ovine) on digoxin immunoassays
12. Monitoring of unbound digoxin in patients treated with anti-digoxin antigen-binding fragments: A model for the future
13. Digoxin assays: Frequent, substantial, and potentially dangerous interference by spironolactone, canrenone, and other steroids
14. Ultrafiltration vs equilibrium dialysis for determination of free fraction
15. Serum digoxin in the presence of Digibind: Determination of digoxin by the Abbott AxSYM and Baxter Stratus II immunoassays by direct analysis without pretreatment of serum samples
16. Comparison of the pharmacokinetics and in vivo bioaffinity of Digitab versus Digibind
17. The affinity of binding of digoxin to ovine anti-digoxin Fab (Digibind) preparations
18. Determination of free serum digoxin concentrations in digoxin toxic patients after administration of digoxin Fab antibodies