CRM1-mediated nuclear export is present during porcine embryogenesis, but is not required for early cleavage

Biology of Reproduction

Volumn 67, Issue 3, 2002, Pages 814-819

  Cabot, Ryan A ^a   Hannink, Mark ^a   Prather, Randall S ^a  

^a UNIVERSITY OF MISSOURI   (United States)

Author keywords

Developmental biology; Early development; Embryo; In vitro fertilization

Indexed keywords

LEPTOMYCIN B; NUCLEAR EXPORT FACTOR; NUCLEAR PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR CRM1; UNCLASSIFIED DRUG;

ACTIVE TRANSPORT; ARTICLE; CELL CYCLE; CONTROLLED STUDY; CYTOPLASM; DEVELOPMENTAL STAGE; EMBRYO; EMBRYO CULTURE; EMBRYO DEVELOPMENT; FERTILIZATION IN VITRO; HUMAN; HUMAN CELL; IMMUNOLOCALIZATION; MICROINJECTION; NUCLEAR IMPORT; OOCYTE CLEAVAGE; PRIORITY JOURNAL; PROTEIN FUNCTION; TRANSCRIPTION REGULATION;

ANIMALS; CLEAVAGE STAGE, OVUM; CULTURE TECHNIQUES; EMBRYO; EMBRYONIC AND FETAL DEVELOPMENT; EMBRYONIC DEVELOPMENT; FATTY ACIDS, UNSATURATED; FEMALE; KARYOPHERINS; PREGNANCY; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SWINE;

MAMMALIA; SUIDAE;

EID: 0036720937     PISSN: 00063363     EISSN: None     Source Type: Journal    
DOI: 10.1095/biolreprod.102.004960     Document Type: Article

References (20)

1. CRM1 is an export receptor for leucine-rich nuclear export signals
2. Exportin 1 (crm1p) is an essential nuclear export factor
3. CRM1 is responsible for intracellular transport mediated by the nuclear export signal
4. Nuclear export of cyclin B1 and its possible role in the DNA damage-induced checkpoint
5. 2 arrest in the Xenopus oocyte: A role for 14-3-3 mediated inhibition of Cdc25 nuclear import
6. An N-terminal nuclear export signal is required for the nucleocytoplasmic shuttling of IκBα
7. Leptomycin B targets a regulatory cascade of crm1, a fission yeast nuclear protein, involved in control of higher order chromosome structure and gene expression
8. Leptomycin B is an inhibitor of nuclear export: Inhibition of nucleo-cytoplasmic translocation of the human immunodeficiency virus type-1 (HIV-1) rev protein and rev-dependent mRNA
9. Leptomycin B inhibition of signal-mediated nuclear export by direct binding to CRM1
10. Effects of leptomycin B on the cell cycle of fibroblasts and fission yeast cells
11. Developmentally regulated activity of CRM1/XPO1 during early Xenopus embryogenesis
12. Maturation in vitro of pig oocytes in protein-free media: Fertilization and subsequent embryo development in vitro
13. Fertilization and subsequent development in vitro of pig oocytes inseminated in a modified Tris-buffered medium with frozen thawed ejaculated spermatozoa
14. Culture of pig embryos
15. Loss of control by IkBa over nuclear localization and DNA-binding enables oncogenic activation of c-rel
16. Evidence for specific nucleocytoplasmic transport pathways used by leucine-rich nuclear export signals
17. Developmental regulation of a snRNP core protein epitope during pig embryogenesis and after nuclear transfer for cloning
18. Development of early porcine embryos in vitro and in vivo
19. High-resolution autoradiographic studies of comparative nucleogenesis and genome reactivation during early embryogenesis in pig, man, and cattle
20. Leptomycin B arrests bovine and porcine embryo development at the major turn on of the embryonic genome