Growth-inhibiting effects of intralesional docetaxel and paclitaxel on an experimental model of malignant neuroectodermal tumor

Journal of Neuro-Oncology

Volumn 59, Issue 3, 2002, Pages 207-212

  Morales, C ^a   Zurita, M ^a   Vaquero, Jesús ^a  

^a HOSPITAL UNIVERSITARIO PUERTA DE HIERRO   (Spain)

Author keywords

Brain neoplasms; Docetaxel; Experimental tumor; Intratumoral chemotherapy; Paclitaxel

Indexed keywords

DOCETAXEL; PACLITAXEL; TAXOID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BRAIN TUMOR; CANCER GROWTH; CANCER INHIBITION; CANCER REGRESSION; CONTROLLED STUDY; DRUG EFFICACY; EDEMA; MOUSE; NEUROECTODERM TUMOR; NONHUMAN; RAT; SKIN NECROSIS; TOXICITY; TUMOR GROWTH;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL DIVISION; ETHYLNITROSOUREA; IMMUNOENZYME TECHNIQUES; INJECTIONS, INTRALESIONAL; MODELS, ANIMAL; NEOPLASMS, EXPERIMENTAL; NEUROECTODERMAL TUMORS; PACLITAXEL; RATS; RATS, WISTAR; TAXOIDS; TIME FACTORS;

EID: 0036714906     PISSN: 0167594X     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1019979813640     Document Type: Article

References (47)

1. Plant antitumor agents IV: The isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifolia
2. Promotion of microtubule assembly in vitro by taxol
3. A highly efficient, practical approach to natural taxol
4. Application of the vicinal oxyamination reaction with asymmetric induction to the hemisynthetisis of taxol and analogues
5. The taxoids: Paclitaxel and docetaxel
6. Paclitaxel: A review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in the treatment of cancer
7. Docetaxel: A review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy in the management of metastatic breast cancer
8. Relationships between the structure of taxol analogues and their antimitotic activity
9. Cellular uptake and efflux of docetaxel (Taxotere) and paclitaxel (Taxol) in P388 cell line
10. Comparative in vitro cytotoxicity of Taxol and Taxotere against cisplantin-sensitive and resistant human ovarian carcinoma cell lines
11. In vitro antiproliferative activity of docetaxel (Taxotere), paclitaxel (Taxol) and cisplatin against human tumors and normal bone marrow cells
12. Effects of Taxotere and Taxol on in vitro colony formation of freshly explanted human tumor cells
13. The cytotoxicity of taxol in vitro against human and rat malignant brain tumors
14. Experimental antitumor activity of Taxotere (RP 56976, NSC 628503), a taxol analogue
15. Response of human tumor xenografts in athymic nude mice to docetaxel (RP 56976, Taxotere)
16. Antitumor activity of Taxotere (RP 56976, NSC 628503), a new taxol analogue, in experimental ovarian cancer
17. Comparison of paclitaxel and docetaxel activity on human ovarian carcinoma xenografts
18. Preclinical evaluation of docetaxel (Taxotere)
19. Taxol: A review of its preclinical in vivo antitumor activity
20. The taxoids: Comparative clinical pharmacology and therapeutic potential
21. Phase II study of paclitaxel in patients with recurrent malignant glioma
22. Salvage chemotherapy with paclitaxel for recurrent primary brain tumors
23. Salvage chemotherapy with paclitaxel for recurrent oligodendrogliomas
24. Phase II trial of docetaxel in patients with recurrent malignant glioma: A study of the National Cancer Institute of Canada Clinical Trials Group
25. Phase I trial of docetaxel administered as a 1 h infusion in children with refractory solid tumors: A collaborative pediatric branch, National Cancer Institute and Children's Cancer Group Trial
26. Experimental induction of primitive neuroectodermal tumors in rats: A reapraisement of the ENU-model of neurocarcinogenesis
27. Therapy of human tumors in athymic (nude) mice
28. Interstitial chemotherapy for brain tumors: Review
29. Proliferation, migration and invasion of human glioma cells exposed to paclitaxel (Taxol) in vitro
30. Cytotoxicity of paclitaxel and docetaxel in human neuroblastoma cell lines
31. Interstitial taxol delivered from a biodegradable polymer implant against experimental malignant glioma
32. Paclitaxel induces programmed cell death in MDA-MB-468 human breast cancer cells
33. Mitotic phosphorylation of Bcl-2 during normal cell cycle progression and Taxol induced growth arrest
34. Taxol induced apoptosis and phosphorylation of bcl-2 protein involves c-Raf-1 signal transduction pathway
35. Relationship of mitotic arrest and apoptosis to anti-tumor effect of paclitaxel
36. Taxol induced bcl-2 phosphorylation and death of prostate cancer cells
37. The microtubule affecting drug paclitaxel has antiangiogenic activity
38. Lack of correlation between mitotic arrest or apoptosis and antitumor effect of docetaxel
39. Lipopolysaccharide antagonists block taxol induced signaling in murine macrophages
40. Docetaxel treatment of HT-29 colon carcinoma cells reinforces the adhesion and immunocytotoxicity of peripheral blood lymphocytes in vitro
41. Effect of taxol and taxotere on gene expression in macrophages: Induction of the prostaglandin H synthase-2 isoenzyme
42. Taxol sensitizes human astrocytoma cells to radiation
43. Investigation of taxol as a potential radiation sensitizer
44. Docetaxel enhances tumor radioresponse in vivo
45. Histologic evidence of a radiosensitizing effect of Taxol in patients with astrocytomas
46. Concurrent twice a week docetaxel and radiotherapy: A dose escalation trial with immunological toxicity evaluation
47. The role of paclitaxel in the treatment of primary and metastatic brain tumors