A KQ121 variant in the PC-1 gene and diabetic nephropathy: Discrepant results between North and South Europe

Nephrology Dialysis Transplantation

Volumn 17, Issue 9, 2002, Pages 1546-1547

  Marre, Michel ^a  

^a BICHAT HOSPITAL   (France)

Author keywords

Diabetic nephropathy; Glomerular filtration rate; KQ121 polymorphism; PC 1 gene

Indexed keywords

ALBUMIN; DNA; MEMBRANE PROTEIN; PC1 PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CARDIOVASCULAR DISEASE; CAUCASIAN; CONTROLLED STUDY; DIABETIC NEPHROPATHY; DIETARY INTAKE; ETHNIC DIFFERENCE; EUROPE; GENE FREQUENCY; GENETIC POLYMORPHISM; GENOTYPE; GLOMERULUS FILTRATION RATE; HUMAN; INSULIN RESISTANCE; KIDNEY DISEASE; MORTALITY; NORTHERN EUROPE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SOUTHERN EUROPE;

EID: 0036713316     PISSN: 09310509     EISSN: None     Source Type: Journal    
DOI: 10.1093/ndt/17.9.1546     Document Type: Article

References (8)

1. The role of PC-1 and ACE genes in diabetic nephropathy in type 1 diabetic patients: Evidence for a polygenic control of kidney disease progression
2. PC-1 amino acid variant (K121Q) has no impact on progression of diabetic nephropathy in type 1 diabetic patients
3. Insulin resistance in family members of insulin-dependent diabetic patients with microalbuminuria
4. A PC-1 amino acid-variant (K121Q) is associated with faster progression of renal disease in patients with type 1 diabetes and albuminuria
5. Effect of deletion polymorphism of angiotensin converting enzyme gene on progression of diabetic nephropathy
6. Microalbuminuria as a predictor of clinical nephropathy in insulin dependent diabetes mellitus
7. Early detection of patients at risk of developing diabetic nephropathy. A longitudinal study of urinary albumin excretion
8. Prognostic value of angiotensin-I converting enzyme D/I polymorphism for nephropathy in type 1 diabetes: A prospective study