Management of patients aged >60 years with malignant glioma: Good clinical status and radiotherapy determine outcome

British Journal of Neurosurgery

Volumn 16, Issue 4, 2002, Pages 343-347

  Whittle, I R ^a   Basu, N ^a   Grant, R ^a   Walker, M ^a   Gregor, A ^a  

^a WESTERN GENERAL HOSPITAL   (United Kingdom)

Author keywords

Clinical status; Glioma; Radiotherapy; Surgery

Indexed keywords

CARBOPLATIN; LOBRADIMIL; LOMUSTINE; PROCARBAZINE; TAUROMUSTINE; VINCRISTINE;

ADULT; AGED; ARTICLE; CANCER CHEMOTHERAPY; CANCER GRADING; CANCER RADIOTHERAPY; CANCER SURGERY; CANCER SURVIVAL; CLINICAL TRIAL; COHORT ANALYSIS; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; GLIOBLASTOMA; HEALTH STATUS; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MEDICAL PRACTICE; NEUROSURGERY; POSTOPERATIVE CARE; PRIORITY JOURNAL; SCALE UP; SURGICAL TECHNIQUE; SURVIVAL TIME; TREATMENT OUTCOME; TUMOR BIOPSY; WORLD HEALTH ORGANIZATION;

EID: 0036699138     PISSN: 02688697     EISSN: None     Source Type: Journal    
DOI: 10.1080/02688690021000007650     Document Type: Article

References (19)

1. Ayobi S, Walter PH, Naik S, et al., Audit in the management of gliomas. Br J Neurosurg 1993;7:61-70.
2. Brandes A, Fiorentino MN. Treatment of high grade gliomas in the elderly. Oncology 1998;55:1-6
3. Fine H. The basis for current treatment recommendations for malignant gliomas. J Neurooncology 1994;20:111-20.
4. Davis FG, Freels S, Grutsch J, et al. Survival rates in patients with primary malignant brain tumours stratified by patient age and tumour histological type: an analysis based on surveillance, epidemiology, and end results (SEER) data. J Neurosurg 1998;88:1-10.
5. Grant R, Whittle IR, Collie DA, et al. Referral pattern and mix of patients with malignant brain tumours in SE Scotland. Hlth Bull (Edin) 1996;54:212-22.
6. Quigley M, Maroon J. The relationship between survival and the extent of resection with supratentorial malignant gliomas. Neurosurgery 1991;29:385-9.
7. Nazzaro J, Neuwelt A. The role of surgery in the management of supratentorial intermediate and high grade astrocytomas in adults. J Neurosurg 1990;73:331-44.
8. Whittle IR, Denholm SW, Gregor A. Management of patients over 60 years with supratentorial glioma: lessons from an audit. Surg Neurol 1991;36:106-11.
9. MRC Brain Tumour Working Party. Prognostic factors for high grade malignant glioma: Development of a prognostic index. J Neuro-oncology 1990;9:47-55.
10. Coffey RJ, Lunsford LD, Taylor FH. Survival after stereotactic biopsy of malignant gliomas. Neurosurgery 1988;22:465-73.
11. Greig NH, Ries LG, Yancik R. Increasing annual incidence of primary malignant brain tumours in the elderly. J Nat Cancer Inst 1990;82:1621-4.
12. Latif AZ, Signorini D, Gregor A, et al. Application of the MRC brain tumour prognostic index to patients with malignant glioma not managed in randomised control trial. J Neurol Neurosurg Psychiatry 1998;64:747-50.
13. Davies E, Hopkins A. Good practice in the management of adults with malignant cerebral glioma: Clinical guidelines. Br J Neurosurg 1997:11(4):318-30.
14. Kaplan EL, Meier P. Nonparametric estimation from incomplete observation. J Am Stat Ass 1988;53: 457-81.
15. Thomas R, James N, Guerrero D, et al. Hypofractioned radiotherapy as palliative treatment in poor prognosis patients with high grade glioma. Radiother Oncol 1994;33:113-16.
16. Kelly PJ, Hunt C. The limited value of cytoreductive surgery in elderly patients with malignant gliomas. Neurosurgery 1994;34:62-7.
17. Newall J, Ransohoff J, Kaplan B. Glioblastoma in the older patient: how long a course of radiotherapy necessary? J Neurooncology 1988;6:325-7.
18. Tomita T, Raimondi A. Brain tumors in the elderly. JAMA 1981;246:53-5.
19. Whittle IR. Management of primary malignant brain tumours. J Neurol Neurosurg Psychiatry 1996;60:2-5.