Treatment of high-grade gliomas in the elderly

Oncology

Volumn 55, Issue 1, 1997, Pages 1-6

  Brandes, Alba ^a   Fiorentino, Mario V ^a  

^a UNIVERSITY HOSPITAL OF PADOVA   (Italy)

Author keywords

Brain tumors; Elderly; High grade gliomas; Review; Treatment

Indexed keywords

ANTINEOPLASTIC AGENT; CARMUSTINE;

AGED; BONE MARROW SUPPRESSION; BRAIN TUMOR; CANCER CHEMOTHERAPY; CANCER GRADING; CANCER RADIOTHERAPY; CANCER SURGERY; GLIOMA; HUMAN; INFECTION; LUNG TOXICITY; PRIORITY JOURNAL; REVIEW; MULTIMODALITY CANCER THERAPY; PATHOLOGY;

AGED; BRAIN NEOPLASMS; COMBINED MODALITY THERAPY; GLIOMA; HUMANS;

EID: 0030722547     PISSN: 00302414     EISSN: None     Source Type: Journal    
DOI: 10.1159/000011827     Document Type: Review

References (23)

1. Greig NH, Lynn GR, Yancik Sl: Rapport: Increasing annual incidence of primary malignant brain tumors in the elderly. J Natl Cancer Inst 1990; 82: 1621-1623.
2. Werner MH, Phuphanich S, Lyman G: The increasing incidence of malignant gliomas and primary central nervous system lymphoma in the elderly. Cancer 1995; 76: 1634-1642.
3. Desmeules M, Mikkelsen T, Mao Y: Increasing incidence of primary malignant brain tumors: influence of diagnostic methods. J Natl Cancer Inst 1992; 84: 442-445.
4. Radhakrishnan K, Mokri B, Parisi J: The trends in incidence of primary brain tumors in the population of Rochester, Minnesota. Ann Neurol 1995; 37: 67-73.
5. Stage WS, Stein JJ: Treatment of malignant astrocytomas. Am J Roentgenol 1974; 120: 7-18.
6. Nelson DF, Nelson JS, Davis DR, et al: Survival and prognosis of patients with astrocytoma with atypical and anaplastic features. J Neurooncol 1985; 3: 99-103.
7. Burger PC, Green SB: Patient age, histologic features, and length of survival in patients with glioblastoma multiforme. Cancer 1987; 59: 1617-1625.
8. Steinfeld AD, Donahue B, Walker I: Delay in the diagnosis of glioblastoma multiforme: is age a factor? Cancer Invest 1996; 14: 317-319.
9. Ampil F, Fowler M, Kim K: Intracranial astrocytoma in elderly patients. J Neurooncol 1992; 12(2): 125-130.
10. Rosenblum ML, Gerosa M, Dougherity DV, et al: Age-related chemiosensitivity of stem cells from human malignant brain tumors. Lancet 1982; 17: 885-887.
11. Whittle IR, Denholm SW, Gregor A: Management of patients aged over 60 years with supratentorial glioma: lessons from an audit. Surg Neurol 1991; 36(2): 106-111.
12. Kelly PJ, Hunt C: The limited value of cytoreductive surgery in elderly patients with malignant gliomas. Neurosurgery, 1994; 34(1): 62-67.
13. Tomita T, Raimondi AJ : Brain tumors and the elderly. JAMA 1981; 246: 53-55.
14. Walker MD, Green SB, Byar DP: Randomized comparisons of radiotherapy and nitrosoureas for the treatment of malignant gliomas after surgery. N Engl J Med 1980; 303: 1323-1328.
15. Meckling S, Dold O, Forsyth P: Malignant supratentorial glioma in the elderly. Is radiotherapy usefull? Neurology 1996; 47: 901-905.
16. Peschel RE, Wilson L, Bruce H: The effect of advanced age on the efficacy of radiation therapy for earlybreast cancer, local prostate cancer and grade III-IV gliomas. Int J Radiat Oncol Biol Phys 1993,26: 539-544.
17. Bauman GS, Gaspar LE, Fisher BJ: A prospective study of short-course radiotherapy in poor prognosis glioblastoma multiforme. Int J Radiat Oncol Biol Phys 1994; 29(4): 835-839.
18. Hernandez JC, Maruyama Y, Yaes R: Accelerated fractionation radiotherapy for hospitalized glioblastoma multiforme patients with poor prognostic factors. J Neurooncol 1990; 9: 41-45.
19. Newall J, Ransohoff J, Kaplan B: Glioblastoma in the older patient. How long a course of radiotherapy is necessary? J Neurooncol 1988; 6: 325-327.
20. Grant R, Liang BC, Page MA: Age influences chemotherapy response in astrocytomas. Neurology 1995; 45: 929-933.
21. Gilbert MR, Bozik M, Armstrong TS, et al: Aggressive chemotherapy treatment of brain tumors in the elderly: Results from phase II study (abstract). ASCO Proc 1996; 15: A271.
22. Lipschitz DA, Udupa KB, Milton KY: Effect of age on hematopoiesis in man. Blood 1984; 63: 502-509.
23. Cohen HJ: Biology of aging as related to cancer. Cancer 1993; 71: 2092-2100.