Biomimetic oxidation of 2-methylimidazole derivative with a chemical model system for cytochrome P-450

Chemical and Pharmaceutical Bulletin

Volumn 50, Issue 8, 2002, Pages 1137-1140

  Miyachi, Hiroyuki ^a   Nagatsu, Yoshio ^a  

^a KYORIN PHARMACEUTICAL CO LTD   (Japan)

Author keywords

2 methylimidazole derivative; 2 methylimidazolone derivative; Drug metabolism; Metabolic intermediate; Metalloporphyrin; P 450 Chemical model

Indexed keywords

4 (2 METHYL 1 IMIDAZOLYL) 2,2 DIPHENYLBUTYRAMIDE; CYTOCHROME P450; IMIDAZOLE DERIVATIVE; UNCLASSIFIED DRUG; 2 METHYLIMIDAZOLE; 2-METHYLIMIDAZOLE;

ARTICLE; DRUG METABOLISM; MELTING POINT; MOLECULAR MODEL; OXIDATION; BIOMIMETICS; CHEMICAL MODEL; CHEMISTRY; METABOLISM; METHODOLOGY; OXIDATION REDUCTION REACTION;

BIOMIMETICS; CYTOCHROME P-450 ENZYME SYSTEM; IMIDAZOLES; MODELS, CHEMICAL; OXIDATION-REDUCTION;

EID: 0036691481     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.50.1137     Document Type: Article

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