Artificial neural network prediction of aerosol deposition in human lungs

Pharmaceutical Research

Volumn 19, Issue 8, 2002, Pages 1130-1136

  Nazir, Javed ^a   Barlow, David J ^a   Lawrence, M Jayne ^a   Richardson, Christopher J ^b   Shrubb, Ian ^c  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^c ASTRAZENECA   (United Kingdom)

Author keywords

Aerosol deposition; Artificial neural networks; Human lungs

Indexed keywords

ACCURACY; AEROSOL; ARTICLE; ARTIFICIAL NEURAL NETWORK; BREATHING; BRONCHUS; DRUG DELIVERY SYSTEM; DRY POWDER; ERROR; LARYNX; LUNG; LUNG ALVEOLUS; MEDICAL NEBULIZER; PARTICLE SIZE; POWDER INHALER; PREDICTION; PRIORITY JOURNAL; RELIABILITY;

AEROSOLS; HUMANS; LUNG; NEURAL NETWORKS (COMPUTER); PARTICLE SIZE; PREDICTIVE VALUE OF TESTS;

EID: 0036689415     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1019889907976     Document Type: Article

References (25)

1. Mechanisms of macromolecule absorption by the lung
2. Latest advances in the development of dry powder inhalers
3. Transitions to cfc-free metered dose inhalers-into the millennium
4. Intelligent inhalers for systemic administration?
5. Aerosol therapy past, present, and future: A clinician's perspective
6. Intercomparison of experimental regional aerosol deposition data
7. Deposition of particles in the human respiratory tract in the size range 0.005-15 μm, J
8. Monte carlo modeling of aerosol deposition in human lungs. Part III: Comparison with experimental data
9. Lung models: Strengths and limitations
10. Neural network computer simulation of medical aerosols
11. An application of artificial neural networks to the prediction of surface ozone concentrations in the United Kingdom
12. Neural network forecasting of Canadian GDP growth
13. Transferability of neural network-based decision support algorithms for early assessment of chest-pain patients
14. The beauty of molecular surfaces as revealed by self-organizing neural networks
15. Formula optimization of theophylline controlled-release tablet based on artificial neural networks
16. Estimating drug/plasma concentration levels by applying neural networks to pharmacokinetic data sets
17. Use of artificial neural networks to predict drug dissolution profiles and evaluation of network performance using similarity factor
18. Learning internal representations by error propagation
19. Event-dependent control of noise enhances learning in neural networks
20. Statistical analysis of aerosol deposition in nose and mouth
21. Use of aerosol respirable fraction to predict lung deposition
22. Deposition of monodisperse insoluble aerosol particles in the 0.005 to 0.2 μm size range within the human respiratory tract
23. Methods of calculating lung delivery and deposition of aerosol particles