Purine metabolism and release during cardioprotection with hyperkalemia and hypothermia

Molecular and Cellular Biochemistry

Volumn 237, Issue 1-2, 2002, Pages 119-127

  Imura, Hajime ^a   Ayres, Ben E ^a   Suleiman, M Saadeh ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

Hyperkalemia; Hypothermia; Ischemia; Lactate; Purine; Reperfusion

Indexed keywords

ADENINE NUCLEOTIDE; ADENOSINE PHOSPHATE; BUFFER; HYPOXANTHINE; INOSINE; LACTATE DEHYDROGENASE; LACTIC ACID; POTASSIUM; PURINE NUCLEOSIDE; XANTHINE;

AMINO ACID TRANSPORT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CONVALESCENCE; ENZYME RELEASE; GUINEA PIG; HEART LEFT VENTRICLE PRESSURE; HEART MUSCLE FIBER MEMBRANE; HEART MUSCLE INJURY; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART PROTECTION; HYPERKALEMIA; HYPOTHERMIA; MEMBRANE DAMAGE; NONHUMAN; PURINE METABOLISM; PURINE SYNTHESIS;

ADENINE; ADENOSINE; ADENOSINE MONOPHOSPHATE; ANIMALS; GUINEA PIGS; HEART; HYPERKALEMIA; HYPOTHERMIA; HYPOXANTHINE; INOSINE; L-LACTATE DEHYDROGENASE; LACTATES; MYOCARDIUM; PURINES; REPERFUSION INJURY; TEMPERATURE; TIME FACTORS; XANTHINE;

ANIMALIA; CAVIA PORCELLUS; SUS SCROFA;

EID: 0036687891     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1016551720672     Document Type: Article

References (30)

1. Elective cardiac arrest
2. Lack of cardioplegic uniformity in clinical myocardial preservation
3. Cardioplegia: The protection of the myocardium during open heart surgery: A review
4. Protection of the ischemic myocardium: Cold chemical cardioplegia, coronary infusates and the importance of cellular calcium control
5. The additive protective effects of hypothermia and chemical cardioplegia during ischemic cardiac arrest in the rat
6. Increased temperature reduces the protective effect of University of Wisconsin solution in the heart
7. Interstitial pH value in the myocardium as indicator of ischemic stress of cardioplegically arrested hearts
8. The additive protective effects of hypothermia and chemical cardioplegia during ischemic cardiac arrest in the dog
9. Cellular and molecular therapeutic targets for treatment of contractile dysfunction after cardioplegic arrest
10. Intraoperative myocardial protection: Current trends and future perspectives
11. Mitochondria: A target for myocardial protection
12. Separation between ischemic and reperfusion injury by site specific entrapment of endogenous adenosine and inosine using NBMPR and EHNA
13. Attenuated purine production during subsequent ischemia in preconditioned rabbit myocardium is unrelated to the mechanism of protection
14. Ischemic preconditioning is not additive to preservation with hypothermia or crystalloid cardioplegia in the globally ischemic rat hear
15. Age-dependent and hypoxia-related differences in myocardial protection during pediatric open heart surgery
16. Preconditioning in globally ischemic isolated rat hearts: Effect on function and metabolic indices of myocardial damage
17. Modulation of adenosine effects in attenuation of ischemia and reperfusion injury in rat heart
18. Metabolic and functional responses of immature and mature rabbit hearts to hypoperfusion, ischemia and reperfusion
19. Maturational differences in bioenergetic state and purine formation during 'supply' and 'demand' ischemia
20. Increased hypoxic stress decreases AMP hydrolysis in rabbit heart
21. The effect of pyruvate on Krebs buffer pH and lactate efflux from ischemic and reperfused isolated rat hearts
22. Substrate metabolism as a determinant for postischemic functional recovery of the heart
23. Optimal myocardial preservation: Cooling, cardioplegia, and conditioning
24. Effect of temperature on the rise in intracellular sodium caused by calcium depletion in ferret ventricular muscle and the mechanism of the alleviation of the calcium paradox by hypothermia
25. Detrimental effects of temperature on the efficacy of the University-of-Wisconsin Solution when used for cardioplegia at moderate hypothermia - Comparison with the St. - Thomas-Hospital solution at 4 and 20°C
26. Effects of hypothermic ischemic on purine catabolism in canine, primate, and human myocardium
27. 2+
28. +-dependent nucleoside transporter (CNT) family: Identification and characterization of novel human and mouse proteins (hCNT3 and mcnt3) broadly selective for pyrimidine nucleosides (system CIB)
29. Update on current techniques of myocardial protection
30. Changes in the intracellular concentration of glutamate and aspartate in hearts of patients undergoing coronary artery surgery