Three-dimensional structure and molecular mechanism of novel enzymes of spore-forming bacteria

Medical Science Monitor

Volumn 8, Issue 8, 2002, Pages

  Jedrzejas, Mark J ^a  

^a CHILDREN S HOSPITAL OAKLAND RESEARCH INSTITUTE   (United States)

Author keywords

Bacillus; Clostridium; Germination protease; Phosphoglycerate mutase; Small, acid soluble proteins

Indexed keywords

BACTERIAL ENZYME; DNA; GERMINATION PROTEASE; PHOSPHOGLYCERATE MUTASE; PROTEINASE; UNCLASSIFIED DRUG; BACTERIAL DNA; BACTERIAL PROTEIN; DNA BINDING PROTEIN; SPORE GERMINATION PROTEASE;

ANTHRAX; ARTICLE; BACILLUS; BACILLUS ANTHRACIS; BACTERIAL SPORE; CLOSTRIDIUM; DNA DAMAGE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME STRUCTURE; GERMINATION; NONHUMAN; SPOROGENESIS; ANIMAL; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; ENZYMOLOGY; HUMAN; METABOLISM; PHYSIOLOGY; PROTEIN CONFORMATION; REVIEW;

ANIMAL; BACILLUS; BACTERIAL PROTEINS; BINDING SITES; CLOSTRIDIUM; DNA, BACTERIAL; DNA-BINDING PROTEINS; ENDOPEPTIDASES; HUMAN; MODELS, MOLECULAR; PHOSPHOGLYCERATE MUTASE; PROTEIN CONFORMATION; SPORES, BACTERIAL; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.; ANIMALS; HUMANS;

EID: 0036686946     PISSN: 12341010     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. What is Bacillus?
2. Preservation records of micro-organisms: Evidence of the tenacity of life
3. Revival and identification of bacterial spores in 25-40-million-year-old dominican amber
4. Understanding Bacillus anthracis pathogenesis
5. Preparation for emergency relief after biological warfare
6. The Sverdlovsk anthrax outbreak of 1979
7. DNA structure, spore formation and spore properties
8. Mechanisms which contribute to the long-term survival of spores of Bacillus species
9. I will survive: Protecting and repairing spore DNA
10. Changes in forespore chromosome structure during sporulation in Bacillus species
11. Mechanism for the prevention of damage to DNA in spores of Bacillus species
12. Instability and decay of the primary structure of DNA
13. Spore structural properties
14. Properties of Bacillus subtilis small, acid-soluble spore proteins with changes in the sequence recognized by their specific protease
15. Bacillus megaterium spore protease: Synthesis and processing of precursor forms during sporulation and germination
16. Bacillus megaterium spore protease: Purification, radioimmunoassay, and analysis of antigen level and localization during growth, sporulation, and spore germination
17. Autoprocessing of the protease that degrades small, acid-soluble proteins of spores of Bacillus species is triggered by low pH, dehydration, and dipicolinic acid
18. Studies of the processing of the protease which initiates degradation of small, acid-soluble proteins during germination of spores of Bacillus species
19. Studies of the structure and mechanism of the protease that degrades small, acid-soluble spore proteins during germination of spores of Bacillus species
20. Structure and mechanism of action of a novel phosphoglycerate mutase from Bacillus stearothermophilus
21. Structural studies of a novel germination protease from spores of Bacillus megaterium
22. Crystal structure of a novel germination protease from spores of Bacillus megaterium: Structural arrangement and zymogen activation
23. Properties of Bacillus megaterium and Bacillus subtilis mutants which lack the protease that degrades small, acid-soluble proteins during spore germination
24. The phosphoglycerate mutases
25. Structural studies on a 2,3-diphospho glyceric acid ndependent phosphoglycerate mutase from Bacillus stearothermophilus
26. Evolution of glycolysis
27. 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase is conserved among different phylogenetic kingdoms
28. A superfamily of metalloenzymes unifies phosphopentomutase and cofactor-independent phosphoglycerate mutase with alkaline phosphatases and sulfatases
29. 2+ and is pH sensitive
30. Cooperative manganese(II) activation of 3-phosphoglycerate mutase of Bacillus megaterium: A biological pH-sensing mechanism in bacterial spore formation and germination
31. Analysis of the relationship between the decrease in pH and accumulation of 3phosphoglyceric acid in developing forespore of Bacillus species
32. Mechanism of catalysis of the cofactor independent phosphoglycerate mutase from Bacillus stearothermophilus: Crystal structure of the complex with 2-phosphoglycerate
33. Manganese(II) activation of 3-phosphoglycerate mutase of Bacillus megaterium: pH-sensitive interconversion of active and inactive forms
34. Structure, function, and evolution of phosphoglycerate mutases: Comparison with fructose-2,6-bisphosphatase, acid phosphatase, and alkaline phosphatase
35. Conserved core structure and active site residues in alkaline phosphatase superfamily enzymes
36. Phosphoglycerate mutase from wheat germ: Studies with 180-labeled substrate, investigations of the phosphatase and phosphoryl transfer activities, and evidence for a phosphoryl-enzyme intermediate
37. Comparison of the binuclear metalloenzymes diphosphoglycerate-independent mutase and alkaline phosphatase: Their mechanism of catalysis via a phosphoserine intermediate