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Volumn 74, Issue 15, 2002, Pages 3726-3735

In vitro biotransformation of (R)- and (S)-thalidomide: Application of circular dichroism spectroscopy to the stereochemical characterization of the hydroxylated metabolites

(7) Meyring, Michael a Mühlbacher, Jörg b Messer, Kim b Kastner Pustet, Nikola c Bringmann, Gerhard b Mannschreck, Albrecht c Blaschke, Gottfried c

a UNIVERSITY OF MÜNSTER (Germany)

b UNIVERSITY OF WÜRZBURG (Germany)

c UNIVERSITY OF REGENSBURG (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BIOTRANSFORMATION;

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROXYLATION; ISOMERS; METABOLITES; SPECTROSCOPY;

STEREOCHEMISTRY;

5' HYDROXYTHALIDOMIDE; DRUG METABOLITE; THALIDOMIDE; UNCLASSIFIED DRUG;

ARTICLE; BIOTRANSFORMATION; CHEMICAL MODIFICATION; CHIRALITY; CIRCULAR DICHROISM; DRUG STRUCTURE; ENANTIOMER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROXYLATION; RELIABILITY; STEREOCHEMISTRY; STRUCTURE ANALYSIS; ANIMAL; LIVER MICROSOME; MALE; METABOLISM; RAT; SPRAGUE DAWLEY RAT; STEREOISOMERISM;

ANIMALS; BIOTRANSFORMATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CIRCULAR DICHROISM; HYDROXYLATION; MALE; MICROSOMES, LIVER; RATS; RATS, SPRAGUE-DAWLEY; STEREOISOMERISM; THALIDOMIDE;

EID: 0036683168 PISSN: 00032700 EISSN: None Source Type: Journal
DOI: 10.1021/ac0203138 Document Type: Article

Times cited : (49)

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