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Volumn 29, Issue 6, 2002, Pages 1061-1071
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In vitro metabolism of a nitroderivative of acetylsalicylic acid (NCX4016) by rat liver: LC and LC-MS studies
a
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Author keywords
In vitro metabolism; Liquid chromatography ion trap mass spectrometry; NCX4016; Nitroaspirin; Rat liver
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Indexed keywords
1 (GLUTATHIONE SULFURYL)METHYLENE 3 HYDROXYBENZENE;
3 (NITROOXYMETHYL)PHENOL;
3 HYDROXYBENZYLALCOHOL;
ACETYLSALICYLIC ACID 3 (NITROXYMETHYL)PHENYL ESTER;
ACETYLSALICYLIC ACID DERIVATIVE;
ALCOHOL DERIVATIVE;
BENZENE DERIVATIVE;
CARBON;
DRUG METABOLITE;
GLUTATHIONE;
GLUTATHIONE TRANSFERASE;
NITRIC OXIDE;
NONSTEROID ANTIINFLAMMATORY AGENT;
PHENOL DERIVATIVE;
PHOSPHORIC ACID;
SALICYLIC ACID;
SULFIDE;
UNCLASSIFIED DRUG;
ANIMAL TISSUE;
CALIBRATION;
CONFERENCE PAPER;
CONJUGATION;
CONTROLLED STUDY;
CYTOSOL;
DETOXIFICATION;
ENZYME ACTIVITY;
EXTRACTION;
IN VITRO STUDY;
INCUBATION TIME;
LIQUID CHROMATOGRAPHY;
LIVER CELL;
LIVER CYTOSOL;
LIVER METABOLISM;
MALE;
MASS SPECTROMETRY;
MICROSOME;
NONHUMAN;
PRIORITY JOURNAL;
PROTON TRANSPORT;
RAT;
REVERSED PHASE LIQUID CHROMATOGRAPHY;
SUPERNATANT;
TIME;
ANIMALS;
ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL;
ASPIRIN;
CHROMATOGRAPHY, HIGH PRESSURE LIQUID;
CYTOSOL;
GLUTATHIONE TRANSFERASE;
MALE;
METABOLIC DETOXICATION, DRUG;
MICROSOMES, LIVER;
RATS;
RATS, WISTAR;
SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;
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EID: 0036681476
PISSN: 07317085
EISSN: None
Source Type: Journal
DOI: 10.1016/S0731-7085(02)00147-4 Document Type: Article |
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Times cited : (36)
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References (11)
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