Effect of misoprostol on ibuprofen-induced renal dysfunction in patients with decompensated cirrhosis: Results of a double-blind placebo-controlled parallel group study

American Journal of Gastroenterology

Volumn 97, Issue 8, 2002, Pages 2033-2039

  Ackerman, Zvi ^a,b   Cominelli, Fabio ^a   Reynolds, Telfer B ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

IBUPROFEN; INULIN; MISOPROSTOL; NONSTEROID ANTIINFLAMMATORY AGENT; PLACEBO; PROSTAGLANDIN E2; SODIUM; WATER;

ADULT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CHILL; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIARRHEA; DOSE RESPONSE; DOSE TIME EFFECT RELATION; DOUBLE BLIND PROCEDURE; DRUG CLEARANCE; DRUG EFFICACY; DRUG SAFETY; FEMALE; FEVER; FREE WATER CLEARANCE; HUMAN; INULIN CLEARANCE; KIDNEY DYSFUNCTION; KIDNEY FAILURE; KIDNEY FUNCTION TEST; LIVER CIRRHOSIS; MALE; OSMOLARITY; PRIORITY JOURNAL; PROSTAGLANDIN METABOLISM; RANDOMIZED CONTROLLED TRIAL; RISK BENEFIT ANALYSIS; SODIUM EXCRETION; STATISTICAL SIGNIFICANCE; URINE VOLUME;

ADULT; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; DOUBLE-BLIND METHOD; FEMALE; GLOMERULAR FILTRATION RATE; HUMANS; IBUPROFEN; KIDNEY DISEASES; LIVER CIRRHOSIS; MALE; MIDDLE AGED; MISOPROSTOL; PLACEBOS; STATISTICS, NONPARAMETRIC; TREATMENT OUTCOME;

EID: 0036679125     PISSN: 00029270     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9270(02)04203-X     Document Type: Article

References (38)

1. Renal complications in liver disease
2. Renal sodium retention in cirrhosis: Tubular site and relation to hepatic dysfunction
3. Disturbances in renal function associated with hepatic dysfunction
4. Systemic and regional hemodynamics in patients with liver cirrhosis and ascites with and without functional renal failure
5. Glomerular hyperfiltration in patients with well compensated alcoholic cirrhosis
6. 2 in the hepatorenal syndrome.Evidence for increased vasoconstrictor and decreased vasodilator factors
7. Renal vasoactive mediator generation in portal hypertensive and bile duct ligated rats
8. Immunohistochemical distribution of renal prostaglandin endoperoxide synthase and prostacyclin synthase: Diminished endoperoxide synthase in the hepatorenal syndrome
9. Localization of cyclooxygenase-1 and -2 in adult fetal human kidney: Implication for renal function
10. Localization of the prostacyclin receptor in human kidney
11. 2 in cirrhosis. Relationship to functional renal failure and sodium and water excretion
12. Importance of renal prostaglandins in control of renal function after chronic ligation of the common bile duct in dogs
13. Evidence that renal prostaglandins are involved in renal water metabolism in cirrhosis
14. Renal eicosanoids as determinants of renal function
15. 1 on renal function and plasma renin activity in alcoholic liver disease
16. Indomethacin induced renal dysfunction in patients with well compensated cirrhosis
17. Renal perfusion in dogs with experimental hepatic cirrhosis
18. Prostaglandins: Modulators of renal function and pressor resistance in chronic liver disease
19. Effects of sulindac and ibuprofen in patients with cirrhosis and ascites. An explanation for the renal sparing effect of sulindac
20. Comparative acute effects of diflunisal and indomethacin on renal function in patients with cirrhosis and ascites
21. Effect of inhibitors of prostaglandin synthesis on induced diuresis in cirrhosis
22. Acetylsalicylic acid suppresses the renal hemodynamic effect and reduces the diuretic action of furosemide in cirrhosis with ascites
23. The effects of chronic administration of indomethacin and misoprostol on renal function in cirrhotic patients with and without ascites
24. The effect of misoprostol on indomethacin induced renal dysfunction in well compensated cirrhosis
25. Anti-ulcer prostaglandin misoprostol: Single and multiple dose pharmacokinetic profile
26. The dose-dependent effect of misoprostol on indomethacin induced renal dysfunction in well compensated cirrhosis
27. Effects of oral prostaglandins on indomethacin induced renal failure in patients with cirrhosis and ascites
28. Adverse effects of non-steroid anti-inflammatory drugs on renal function
29. 4 and inflammatory in rabbit colitis
30. Gastrointestinal toxicity of non-steroidal anti-inflammatory drugs
31. Nephrotoxicity of non-steroid anti-inflammatory drugs: Physiologic foundations and clinical implications
32. Pharmacokinetics of misoprostol in the elderly, in patients with renal failure and when co-administered with NSAIDs or antipyrine, propranol or dizepam
33. Interactions between prostaglandins and calcium: The importance of bell-shaped dose response curves
34. Misoprostol-associated fever in a cirrhotic patient
35. Selective inhibition of cycloxygenase-2 spares renal function and prostaglandin synthesis in cirrhotic rats with ascites
36. Nimesulide and renal impairment
37. Are selective cycloxygenase-2 inhibitors nephrotoxic?
38. Rofecoxib induced renal dysfunction in a patient with compensated cirrhosis and heart failure