메뉴 건너뛰기




Volumn 3, Issue 4, 2002, Pages 285-291

Phytotherapy for benign prostatic hyperplasia

Author keywords

Benign Prostatic Hyperplasia; Finasteride; Herbal Product; International Prostate Symptom Score; Lower Urinary Tract Symptom

Indexed keywords

ANTIANDROGEN; PLANT EXTRACT; SABAL EXTRACT; SITOSTEROL; SITOSTEROL DERIVATIVE;

EID: 0036673059     PISSN: 15272737     EISSN: 15346285     Source Type: Journal    
DOI: 10.1007/s11934-002-0050-3     Document Type: Article
Times cited : (35)

References (42)
  • 1
    • 0035655618 scopus 로고    scopus 로고
    • Phytotherapy in the management of benign prostatic hyperplasia
    • PID: 11750257, COI: 1:STN:280:DC%2BD38%2FgtFSmsg%3D%3D, An excellent overview of the use of phytotherapy by men with BPH
    • Lowe FC: Phytotherapy in the management of benign prostatic hyperplasia. Urology 2001, 58(Suppl 1):71–76. An excellent overview of the use of phytotherapy by men with BPH. DOI: 10.1016/S0090-4295(01)01303-6
    • (2001) Urology , vol.58 , pp. 71-76
    • Lowe, F.C.1
  • 2
    • 0021213498 scopus 로고
    • A double-blind trial of an extract of the plant Serenoa repens in benign prostatic hyperplasia
    • PID: 6207850, COI: 1:STN:280:DyaL2M%2FitlSrug%3D%3D
    • Champault G, Patel JC, Bonnard AM: A double-blind trial of an extract of the plant Serenoa repens in benign prostatic hyperplasia. Br J Clin Pharmacol 1984, 18:461–462.
    • (1984) Br J Clin Pharmacol , vol.18 , pp. 461-462
    • Champault, G.1    Patel, J.C.2    Bonnard, A.M.3
  • 3
    • 0021931864 scopus 로고
    • Serenoa repens extract vs. placebo
    • Cukier J, Ducassou J, Le Guillou M, et al.: Serenoa repens extract vs. placebo. Pharmacol Clin 1985, 4:15–21.
    • (1985) Pharmacol Clin , vol.4 , pp. 15-21
    • Cukier, J.1    Ducassou, J.2    Le, G.M.3
  • 4
    • 0000900975 scopus 로고
    • Clinical results on a new drug in the treatment of benign prostatic hyperplasia (Permixon)
    • Emile E, LoCigno M, Petrone U: Clinical results on a new drug in the treatment of benign prostatic hyperplasia (Permixon). Urologia 1983, 50:1042–1049.
    • (1983) Urologia , vol.50 , pp. 1042-1049
    • Emile, E.1    LoCigno, M.2    Petrone, U.3
  • 5
    • 0022621170 scopus 로고
    • The value of Permixon in benign prostatic hypertrophy
    • Smith HR, Memon A, Smart CJ, et al.: The value of Permixon in benign prostatic hypertrophy. Br J Urol 1986, 58:36–40.
    • (1986) Br J Urol , vol.58 , pp. 36-40
    • Smith, H.R.1    Memon, A.2    Smart, C.J.3
  • 6
    • 0028301655 scopus 로고
    • Inhibition of the activity of basic 5-alpha reductase (type 1) detected in DU 145 cells and expressed in insect cells
    • PID: 8142312, COI: 1:CAS:528:DyaK2cXisVWnur4%3D
    • Delos S, Iehle C, Martin PM: Inhibition of the activity of basic 5-alpha reductase (type 1) detected in DU 145 cells and expressed in insect cells. J Steroid Biochem Mol Biol 1994, 48:347–352. DOI: 10.1016/0960-0760(94)90074-4
    • (1994) J Steroid Biochem Mol Biol , vol.48 , pp. 347-352
    • Delos, S.1    Iehle, C.2    Martin, P.M.3
  • 7
    • 0013569114 scopus 로고    scopus 로고
    • Characterisation of a new coculture model for BPH which expresses 5-alpha reductase types 1 and 2: the effects of Permixon on DHT formation [abstract]
    • Bayne CW, Grant ES, Chapman K, et al.: Characterisation of a new coculture model for BPH which expresses 5-alpha reductase types 1 and 2: the effects of Permixon on DHT formation [abstract]. J Urol 1997, 157(Suppl 4):755.
    • (1997) J Urol , vol.157 , pp. 755
    • Bayne, C.W.1    Grant, E.S.2    Chapman, K.3
  • 8
    • 0021282157 scopus 로고
    • Inhibition of androgen metabolism and binding by liposterolic extract of “Serenoa repens B” in human foreskin fibroblasts
    • PID: 6708534, COI: 1:STN:280:DyaL2c7ms1eiug%3D%3D
    • Sultan C, Terraza A, Devillier C, et al.: Inhibition of androgen metabolism and binding by liposterolic extract of “Serenoa repens B” in human foreskin fibroblasts. J Steroid Biochem 1984, 20:515–519. DOI: 10.1016/0022-4731(84)90264-4
    • (1984) J Steroid Biochem , vol.20 , pp. 515-519
    • Sultan, C.1    Terraza, A.2    Devillier, C.3
  • 9
    • 0021245734 scopus 로고
    • Binding of Permixon, a new treatment for prostatic benign hyperplasia, to the cytosolic androgen receptor in the rat prostate
    • PID: 6200701, COI: 1:STN:280:DyaL2c7ms1eiuw%3D%3D
    • Carilla E, Briley M, Fauran F, et al.: Binding of Permixon, a new treatment for prostatic benign hyperplasia, to the cytosolic androgen receptor in the rat prostate. J Steroid Biochem 1984, 20:521–523. DOI: 10.1016/0022-4731(84)90265-6
    • (1984) J Steroid Biochem , vol.20 , pp. 521-523
    • Carilla, E.1    Briley, M.2    Fauran, F.3
  • 10
    • 0013510698 scopus 로고    scopus 로고
    • Response to tissue androgen and epidermal growth factor concentrations to the administration of finasteride, flutamide and Serenoa repens in patients with BPH [abstract]
    • Di Silverio F, Sciarra A, D’Eramo G, et al.: Response to tissue androgen and epidermal growth factor concentrations to the administration of finasteride, flutamide and Serenoa repens in patients with BPH [abstract]. Eur Urol 1996, 30(Suppl 2):80.
    • (1996) Eur Urol , vol.30 , pp. 80
    • Di Silverio, F.1    Sciarra, A.2    D’Eramo, G.3
  • 11
    • 0027476325 scopus 로고
    • Comparison of finasteride (Proscar), a 5-alpha reductase inhibitor, and various commercial plant extracts in vitro and in vivo 5-alpha reductase inhibition
    • PID: 8381228, COI: 1:CAS:528:DyaK2cXmslajt7c%3D
    • Rhodes L, Primka RL, Berman C, et al.: Comparison of finasteride (Proscar), a 5-alpha reductase inhibitor, and various commercial plant extracts in vitro and in vivo 5-alpha reductase inhibition. Prostate 1993, 22:43–51. DOI: 10.1002/pros.2990220107
    • (1993) Prostate , vol.22 , pp. 43-51
    • Rhodes, L.1    Primka, R.L.2    Berman, C.3
  • 12
    • 0028050246 scopus 로고
    • Comparison of finasteride (Proscar) and Serenoa repens (Permixon) in the inhibition of 5-alpha reductase in healthy male volunteers
    • PID: 7805711, COI: 1:STN:280:DyaK2M7gsValtA%3D%3D
    • Strauch G, Perles P, Vergult G, et al.: Comparison of finasteride (Proscar) and Serenoa repens (Permixon) in the inhibition of 5-alpha reductase in healthy male volunteers. Eur Urol 1994, 26:247–252.
    • (1994) Eur Urol , vol.26 , pp. 247-252
    • Strauch, G.1    Perles, P.2    Vergult, G.3
  • 13
    • 0347318854 scopus 로고    scopus 로고
    • Comparison of phytotherapy (Permixon) with finasteride in the treatment of benign prostate hyperplasia: a randomized international study of 1098 patients
    • PID: 8876706
    • Carraro JC, Raynaud JP, Koch G, et al.: Comparison of phytotherapy (Permixon) with finasteride in the treatment of benign prostate hyperplasia: a randomized international study of 1098 patients. Prostate 1996, 29:231–240. DOI: 10.1002/(SICI)1097-0045(199610)29:4<231::AID-PROS4>3.0.CO;2-E
    • (1996) Prostate , vol.29 , pp. 231-240
    • Carraro, J.C.1    Raynaud, J.P.2    Koch, G.3
  • 14
    • 0032100516 scopus 로고    scopus 로고
    • Saw palmetto (Serenoa repens) in men with lower urinary tract symptoms: effects on urodynamic parameters and voiding symptoms
    • PID: 9609640, COI: 1:STN:280:DyaK1c3ntVyjsQ%3D%3D
    • Gerber GS, Zagaja GP, Bales GT, et al.: Saw palmetto (Serenoa repens) in men with lower urinary tract symptoms: effects on urodynamic parameters and voiding symptoms. Urology 1998, 51:1003–1007. DOI: 10.1016/S0090-4295(98)00143-5
    • (1998) Urology , vol.51 , pp. 1003-1007
    • Gerber, G.S.1    Zagaja, G.P.2    Bales, G.T.3
  • 15
    • 0028068214 scopus 로고
    • The extract of Serenoa repens in the treatment of benign prostatic hyperplasia: a multicenter open study
    • Braeckman J: The extract of Serenoa repens in the treatment of benign prostatic hyperplasia: a multicenter open study. Curr Ther Res 1994, 55:776–785. DOI: 10.1016/S0011-393X(05)80771-4
    • (1994) Curr Ther Res , vol.55 , pp. 776-785
    • Braeckman, J.1
  • 16
    • 0026469615 scopus 로고
    • Evidence that Serenoa repens extract displays an antiestrogenic activity in prostatic tissue of benign prostatic hypertrophy patients
    • PID: 1281103
    • Di Silverio F, D’Eramo G, Lubrano C, et al.: Evidence that Serenoa repens extract displays an antiestrogenic activity in prostatic tissue of benign prostatic hypertrophy patients. Eur Urol 1992, 21:309–314.
    • (1992) Eur Urol , vol.21 , pp. 309-314
    • Di Silverio, F.1    D’Eramo, G.2    Lubrano, C.3
  • 17
    • 0001528566 scopus 로고
    • Morphology of benign prostatic hyperplasia after treatment with sabal extract IDS 89 or placebo
    • Helpap B, Oehler U, Weisser H, et al.: Morphology of benign prostatic hyperplasia after treatment with sabal extract IDS 89 or placebo. J Urol Pathol 1995, 3:175–182.
    • (1995) J Urol Pathol , vol.3 , pp. 175-182
    • Helpap, B.1    Oehler, U.2    Weisser, H.3
  • 18
    • 18144436109 scopus 로고    scopus 로고
    • Effects of a saw palmetto herbal blend in men with symptomatic benign prostatic hyperplasia
    • PID: 10751856, COI: 1:STN:280:DC%2BD3c3hslSjtA%3D%3D, One of the first studies to convincingly demonstrate histologic changes the prostate gland associated with saw palmetto use. This may begin to help explain the clinical effectiveness of saw palmetto men with BPH
    • Marks LS, Partin AP, Epstein JI, et al.: Effects of a saw palmetto herbal blend in men with symptomatic benign prostatic hyperplasia. J Urol 2000, 163:1451–1456. One of the first studies to convincingly demonstrate histologic changes in the prostate gland associated with saw palmetto use. This may begin to help explain the clinical effectiveness of saw palmetto in men with BPH. DOI: 10.1016/S0022-5347(05)67641-0
    • (2000) J Urol , vol.163 , pp. 1451-1456
    • Marks, L.S.1    Partin, A.P.2    Epstein, J.I.3
  • 19
    • 0029066391 scopus 로고
    • Placebo controlled evaluation of the efficacy and tolerability of Permixon in benign prostatic hyperplasia after exclusion of placebo responders
    • Descotes JL, Rambeaud JJ, Deschaseaux P, et al.: Placebo controlled evaluation of the efficacy and tolerability of Permixon in benign prostatic hyperplasia after exclusion of placebo responders. Clin Drug Invest 1995, 9:291–297.
    • (1995) Clin Drug Invest , vol.9 , pp. 291-297
    • Descotes, J.L.1    Rambeaud, J.J.2    Deschaseaux, P.3
  • 20
    • 0029859371 scopus 로고    scopus 로고
    • Serenoa repens (Permixon). A review of its pharmacology and therapeutic efficacy in benign prostatic hyperplasia
    • PID: 8922564, COI: 1:STN:280:DyaK2s%2FotFeiuw%3D%3D
    • Plosker GL, Brogden RN: Serenoa repens (Permixon). A review of its pharmacology and therapeutic efficacy in benign prostatic hyperplasia. Drugs Aging 1996, 9:379–395.
    • (1996) Drugs Aging , vol.9 , pp. 379-395
    • Plosker, G.L.1    Brogden, R.N.2
  • 21
    • 0022621170 scopus 로고
    • The value of Permixon in benign prostatic hypertrophy
    • Smith HR, Memon A, Smart CJ, et al.: The value of Permixon in benign prostatic hypertrophy. Br J Urol 1986, 58:36–40.
    • (1986) Br J Urol , vol.58 , pp. 36-40
    • Smith, H.R.1    Memon, A.2    Smart, C.J.3
  • 22
    • 0035667564 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled trial of saw palmetto in men with lower urinary tract symptoms
    • PID: 11744467, COI: 1:STN:280:DC%2BD3MnpvV2ntw%3D%3D, The results of this trial indicated significant improvement urinary symptoms using saw palmetto compared with placebo. No significant change peak urinary flow rate was noted
    • Gerber GS, Kuznetsov D, Johnson BC, et al.: Randomized, double-blind, placebo-controlled trial of saw palmetto in men with lower urinary tract symptoms. Urology 2001, 58:960–965. The results of this trial indicated significant improvement in urinary symptoms using saw palmetto compared with placebo. No significant change in peak urinary flow rate was noted. DOI: 10.1016/S0090-4295(01)01442-X
    • (2001) Urology , vol.58 , pp. 960-965
    • Gerber, G.S.1    Kuznetsov, D.2    Johnson, B.C.3
  • 23
    • 0032508943 scopus 로고    scopus 로고
    • Saw palmetto extracts for treatment of benign prostatic hyperplasia. A systematic review
    • PID: 9820264, COI: 1:STN:280:DyaK1M%2Fjs1Wmsg%3D%3D, This meta-analysis of close to 3000 men concluded that saw palmetto was superior to placebo relieving urinary symptoms men with BPH. Although this study generated a great deal of coverage the lay press, its findings are somewhat limited by the inclusion of many poorly conducted studies
    • Wilt TJ, Ishani A, Stark G, et al.: Saw palmetto extracts for treatment of benign prostatic hyperplasia. A systematic review. JAMA 1998, 280:1604–1609. This meta-analysis of close to 3000 men concluded that saw palmetto was superior to placebo in relieving urinary symptoms in men with BPH. Although this study generated a great deal of coverage in the lay press, its findings are somewhat limited by the inclusion of many poorly conducted studies. DOI: 10.1001/jama.280.18.1604
    • (1998) JAMA , vol.280 , pp. 1604-1609
    • Wilt, T.J.1    Ishani, A.2    Stark, G.3
  • 24
    • 0034058050 scopus 로고    scopus 로고
    • Meta-analysis of clinical trials of Permixon in the treatment of symptomatic benign prostatic hyperplasia
    • PID: 10736497, COI: 1:STN:280:DC%2BD3c3gt1Ogug%3D%3D, Significant improvement urinary flow rates and symptoms were reported using a meta-analysis of 13 published trials of Permixon
    • Boyle P, Robertson C, Lowe F, et al.: Meta-analysis of clinical trials of Permixon in the treatment of symptomatic benign prostatic hyperplasia. Urology 2000, 55:533–539. Significant improvement in urinary flow rates and symptoms were reported using a meta-analysis of 13 published trials of Permixon. DOI: 10.1016/S0090-4295(99)00593-2
    • (2000) Urology , vol.55 , pp. 533-539
    • Boyle, P.1    Robertson, C.2    Lowe, F.3
  • 25
    • 85130033712 scopus 로고    scopus 로고
    • Prostatic volume does not correlate with efficacy of treatment for mild to moderate benign prostatic hyperplasia using either finasteride or phytotherapy (Permixon). Paper presented at the 4th International Consultation on BPH. Paris
    • Chopin DK, Perrin P, Authie D, et al.: Prostatic volume does not correlate with efficacy of treatment for mild to moderate benign prostatic hyperplasia using either finasteride or phytotherapy (Permixon). Paper presented at the 4th International Consultation on BPH. Paris, July 2–5, 1997.
    • (1997) July , pp. 2-5
    • Chopin, D.K.1    Perrin, P.2    Authie, D.3
  • 26
    • 9444268678 scopus 로고    scopus 로고
    • The efficacy of terazosin, finasteride, or both in benign prostatic hyperplasia
    • PID: 8684407, COI: 1:CAS:528:DyaK28Xlslymtr0%3D
    • Lepor H, Williford WO, Barry MJ, et al.: The efficacy of terazosin, finasteride, or both in benign prostatic hyperplasia. N Engl J Med 1996, 335:533–539. DOI: 10.1056/NEJM199608223350801
    • (1996) N Engl J Med , vol.335 , pp. 533-539
    • Lepor, H.1    Williford, W.O.2    Barry, M.J.3
  • 27
    • 0030901813 scopus 로고    scopus 로고
    • Antiproliferative effect of Pygeum africanum extract on rat prostatic fibroblasts
    • PID: 9146675, COI: 1:CAS:528:DyaK1cXmsVehtbw%3D
    • Yablonsky F, Nicolas V, Riffaud JP, et al.: Antiproliferative effect of Pygeum africanum extract on rat prostatic fibroblasts. J Urol 1997, 157:2381–2387. DOI: 10.1016/S0022-5347(01)64785-2
    • (1997) J Urol , vol.157 , pp. 2381-2387
    • Yablonsky, F.1    Nicolas, V.2    Riffaud, J.P.3
  • 28
    • 0028648255 scopus 로고
    • Inhibition of bFGF and EGF-induced proliferation of 3T3 fibroblasts by extract of Pygeum africanum (Tadenan)
    • Paubert-Braquert M, Monboisse JC, Servent-Saez N, et al.: Inhibition of bFGF and EGF-induced proliferation of 3T3 fibroblasts by extract of Pygeum africanum (Tadenan). Biomed Pharmacother 1994, 48(Suppl 1):43–47.
    • (1994) Biomed Pharmacother , vol.48 , pp. 43-47
    • Paubert-Braquert, M.1    Monboisse, J.C.2    Servent-Saez, N.3
  • 29
    • 0029910172 scopus 로고    scopus 로고
    • Effects of Tadenan pretreatment on bladder physiology and biochemistry following partial outlet obstruction
    • PID: 8911395, COI: 1:CAS:528:DyaK28XntValurg%3D
    • Levin RM, Riffaud JP, Bellamy F, et al.: Effects of Tadenan pretreatment on bladder physiology and biochemistry following partial outlet obstruction. J Urol 1996, 156:2084–2088. DOI: 10.1016/S0022-5347(01)65440-5
    • (1996) J Urol , vol.156 , pp. 2084-2088
    • Levin, R.M.1    Riffaud, J.P.2    Bellamy, F.3
  • 30
    • 0029961775 scopus 로고    scopus 로고
    • Protective effect of Tadenan on bladder function secondary to partial outlet obstruction
    • PID: 8632612
    • Krasnopolsky L, Zhao Y, Wein AJ: Protective effect of Tadenan on bladder function secondary to partial outlet obstruction. J Urol 1996, 155:1466–1470. DOI: 10.1016/S0022-5347(01)66308-0
    • (1996) J Urol , vol.155 , pp. 1466-1470
    • Krasnopolsky, L.1    Zhao, Y.2    Wein, A.J.3
  • 31
    • 0033956398 scopus 로고    scopus 로고
    • Functional evaluation of Tadenan on micturition and experimental prostate growth induced with exogenous dihydrotestosterone
    • PID: 10688098, COI: 1:STN:280:DC%2BD3c7ltVyjtA%3D%3D
    • Choo MS, Bellamy F, Constantinou CE: Functional evaluation of Tadenan on micturition and experimental prostate growth induced with exogenous dihydrotestosterone. Urology 2000, 55:292–298. DOI: 10.1016/S0090-4295(99)00407-0
    • (2000) Urology , vol.55 , pp. 292-298
    • Choo, M.S.1    Bellamy, F.2    Constantinou, C.E.3
  • 32
    • 0021152964 scopus 로고
    • Controlled study of the effects of Pygeum africanum extract on the functional symptoms of prostatic adenoma
    • COI: 1:STN:280:DyaL2M7kslGmtg%3D%3D, Small study of brief duration that suggested a significant improvement urinary symptoms using Pygeum africanum compared with placebo
    • Dufour B, Choquenet C, Revol M, et al.: Controlled study of the effects of Pygeum africanum extract on the functional symptoms of prostatic adenoma. Ann Urol 1984, 18:193–195. Small study of brief duration that suggested a significant improvement in urinary symptoms using Pygeum africanum compared with placebo.
    • (1984) Ann Urol , vol.18 , pp. 193-195
    • Dufour, B.1    Choquenet, C.2    Revol, M.3
  • 33
    • 0025146956 scopus 로고
    • Wirksamkeit eines extraktes aus Pygeum africanum in der medikamentosen therapie von miktionsstorungen infolge einer benignen prostathyperplasi: betwertung objectiver und subjektiver parameter
    • PID: 1702916, COI: 1:STN:280:DyaK3M7gt12mtQ%3D%3D
    • Barlet A, Albrecht J, Aubert A, et al.: Wirksamkeit eines extraktes aus Pygeum africanum in der medikamentosen therapie von miktionsstorungen infolge einer benignen prostathyperplasi: betwertung objectiver und subjektiver parameter. Wien Klin Wochenschr 1990, 102:667–673.
    • (1990) Wien Klin Wochenschr , vol.102 , pp. 667-673
    • Barlet, A.1    Albrecht, J.2    Aubert, A.3
  • 34
    • 0025603727 scopus 로고
    • Treatment of benign prostatic hyperplasia with phytosterols
    • Carbin BE, Larsson B, Lindahl O: Treatment of benign prostatic hyperplasia with phytosterols. Br J Urol 1987, 66:639–641.
    • (1987) Br J Urol , vol.66 , pp. 639-641
    • Carbin, B.E.1    Larsson, B.2    Lindahl, O.3
  • 35
    • 0029078027 scopus 로고
    • Randomised, placebo-controlled, double-blind clinical trial of beta-sitosterol in patients with benign prostatic hyperplasia
    • PID: 7540705, COI: 1:STN:280:DyaK2MzhtFGntA%3D%3D
    • Berges RR, Windeier J, Trampisch HJ, et al.: Randomised, placebo-controlled, double-blind clinical trial of beta-sitosterol in patients with benign prostatic hyperplasia. Lancet 1995, 345:1529–1532. DOI: 10.1016/S0140-6736(95)91085-9
    • (1995) Lancet , vol.345 , pp. 1529-1532
    • Berges, R.R.1    Windeier, J.2    Trampisch, H.J.3
  • 36
    • 0034052168 scopus 로고    scopus 로고
    • Treatment of symptomatic benign prostatic hyperplasia with beta-sitosterol: an 18 month follow-up
    • COI: 1:CAS:528:DC%2BD3cXjvFShur4%3D, This open-label extension study using Harzol demonstrated persistently positive results using this form of beta-sitosterol after an 18-month follow-up
    • Berges RR, Kassen A, Senge T: Treatment of symptomatic benign prostatic hyperplasia with beta-sitosterol: an 18 month follow-up. Br J Urol 2000, 85:842–846. This open-label extension study using Harzol demonstrated persistently positive results using this form of beta-sitosterol after an 18-month follow-up.
    • (2000) Br J Urol , vol.85 , pp. 842-846
    • Berges, R.R.1    Kassen, A.2    Senge, T.3
  • 37
    • 0025218948 scopus 로고
    • Konservative, nicht-hormonelle Behandlung der benignen prostata-hyperplasia
    • PID: 1690486, COI: 1:STN:280:DyaK3c7psVGjsg%3D%3D
    • Dreikorn K, Richter R, Schnohofer PS: Konservative, nicht-hormonelle Behandlung der benignen prostata-hyperplasia. Urologe A 1990, 29:8–16.
    • (1990) Urologe A , vol.29 , pp. 8-16
    • Dreikorn, K.1    Richter, R.2    Schnohofer, P.S.3
  • 38
    • 85130014062 scopus 로고    scopus 로고
    • Randomized, double blinded placebo controlled trial to evaluate the efficacy of B-sitosterol (Phytosterol) in patients with obstructive and irritative symptoms due to BPH. Paper presented at the 4th International Consultation on BPH. Paris
    • Klippel KF, Hiltl DM, Schipp B: Randomized, double blinded placebo controlled trial to evaluate the efficacy of B-sitosterol (phytosterol) in patients with obstructive and irritative symptoms due to BPH. Paper presented at the 4th International Consultation on BPH. Paris, July 2–5, 1997.
    • (1997) July , pp. 2-5
    • Klippel, K.F.1    Hiltl, D.M.2    Schipp, B.3
  • 39
    • 0025119848 scopus 로고
    • Treatment of outflow tract obstruction due to benign prostatic hyperplasia with the pollen extract, Cernilton. A double-blind, placebo-controlled study
    • PID: 1699628, COI: 1:STN:280:DyaK3M%2FivVKjsQ%3D%3D
    • Buck AC, Cox R, Rees WM, et al.: Treatment of outflow tract obstruction due to benign prostatic hyperplasia with the pollen extract, Cernilton. A double-blind, placebo-controlled study. Br J Urol 1990, 66:398–404. DOI: 10.1111/j.1464-410X.1990.tb14962.x
    • (1990) Br J Urol , vol.66 , pp. 398-404
    • Buck, A.C.1    Cox, R.2    Rees, W.M.3
  • 40
    • 0029984815 scopus 로고    scopus 로고
    • Usefulness of Cernilton in the treatment of benign prostatic hyperplasia
    • PID: 8738619, COI: 1:STN:280:DyaK28zjtFGltQ%3D%3D
    • Dutkiewicz S: Usefulness of Cernilton in the treatment of benign prostatic hyperplasia. Int Urol Nephrol 1996, 28:49–53. DOI: 10.1007/BF02550137
    • (1996) Int Urol Nephrol , vol.28 , pp. 49-53
    • Dutkiewicz, S.1
  • 41
    • 0022635679 scopus 로고
    • Cernitin pollen-extract (Cernilton): antiprostatic hyperptrophic action of Cernitin pollenextract (Cernilton)
    • COI: 1:CAS:528:DyaL28XhsVWru7s%3D
    • Ito R, Ishii M, Yamashita S: Cernitin pollen-extract (Cernilton): antiprostatic hyperptrophic action of Cernitin pollenextract (Cernilton). Pharmacometrics 1986, 31:1–11.
    • (1986) Pharmacometrics , vol.31 , pp. 1-11
    • Ito, R.1    Ishii, M.2    Yamashita, S.3
  • 42
    • 0027175210 scopus 로고
    • Results of treatment with pollen extract (Cernilton N) in chronic prostatitis and prostatodynia
    • PID: 8499988, COI: 1:STN:280:DyaK3s3nt1SqsQ%3D%3D
    • Rugendorff EW, Weidner W, Ebeling L, et al.: Results of treatment with pollen extract (Cernilton N) in chronic prostatitis and prostatodynia. Br J Urol 1993, 71:433–438.
    • (1993) Br J Urol , vol.71 , pp. 433-438
    • Rugendorff, E.W.1    Weidner, W.2    Ebeling, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.