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Lowe, F.C.1
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A double-blind trial of an extract of the plant Serenoa repens in benign prostatic hyperplasia
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PID: 6207850, COI: 1:STN:280:DyaL2M%2FitlSrug%3D%3D
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Inhibition of the activity of basic 5-alpha reductase (type 1) detected in DU 145 cells and expressed in insect cells
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Characterisation of a new coculture model for BPH which expresses 5-alpha reductase types 1 and 2: the effects of Permixon on DHT formation [abstract]
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Bayne CW, Grant ES, Chapman K, et al.: Characterisation of a new coculture model for BPH which expresses 5-alpha reductase types 1 and 2: the effects of Permixon on DHT formation [abstract]. J Urol 1997, 157(Suppl 4):755.
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8
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Inhibition of androgen metabolism and binding by liposterolic extract of “Serenoa repens B” in human foreskin fibroblasts
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9
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Binding of Permixon, a new treatment for prostatic benign hyperplasia, to the cytosolic androgen receptor in the rat prostate
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PID: 6200701, COI: 1:STN:280:DyaL2c7ms1eiuw%3D%3D
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Di Silverio F, Sciarra A, D’Eramo G, et al.: Response to tissue androgen and epidermal growth factor concentrations to the administration of finasteride, flutamide and Serenoa repens in patients with BPH [abstract]. Eur Urol 1996, 30(Suppl 2):80.
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0028050246
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Comparison of finasteride (Proscar) and Serenoa repens (Permixon) in the inhibition of 5-alpha reductase in healthy male volunteers
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Carraro JC, Raynaud JP, Koch G, et al.: Comparison of phytotherapy (Permixon) with finasteride in the treatment of benign prostate hyperplasia: a randomized international study of 1098 patients. Prostate 1996, 29:231–240. DOI: 10.1002/(SICI)1097-0045(199610)29:4<231::AID-PROS4>3.0.CO;2-E
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0032100516
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Saw palmetto (Serenoa repens) in men with lower urinary tract symptoms: effects on urodynamic parameters and voiding symptoms
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PID: 9609640, COI: 1:STN:280:DyaK1c3ntVyjsQ%3D%3D
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Gerber GS, Zagaja GP, Bales GT, et al.: Saw palmetto (Serenoa repens) in men with lower urinary tract symptoms: effects on urodynamic parameters and voiding symptoms. Urology 1998, 51:1003–1007. DOI: 10.1016/S0090-4295(98)00143-5
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Braeckman J: The extract of Serenoa repens in the treatment of benign prostatic hyperplasia: a multicenter open study. Curr Ther Res 1994, 55:776–785. DOI: 10.1016/S0011-393X(05)80771-4
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0026469615
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Di Silverio F, D’Eramo G, Lubrano C, et al.: Evidence that Serenoa repens extract displays an antiestrogenic activity in prostatic tissue of benign prostatic hypertrophy patients. Eur Urol 1992, 21:309–314.
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0001528566
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Morphology of benign prostatic hyperplasia after treatment with sabal extract IDS 89 or placebo
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18
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18144436109
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Effects of a saw palmetto herbal blend in men with symptomatic benign prostatic hyperplasia
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PID: 10751856, COI: 1:STN:280:DC%2BD3c3hslSjtA%3D%3D, One of the first studies to convincingly demonstrate histologic changes the prostate gland associated with saw palmetto use. This may begin to help explain the clinical effectiveness of saw palmetto men with BPH
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Marks LS, Partin AP, Epstein JI, et al.: Effects of a saw palmetto herbal blend in men with symptomatic benign prostatic hyperplasia. J Urol 2000, 163:1451–1456. One of the first studies to convincingly demonstrate histologic changes in the prostate gland associated with saw palmetto use. This may begin to help explain the clinical effectiveness of saw palmetto in men with BPH. DOI: 10.1016/S0022-5347(05)67641-0
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Marks, L.S.1
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Placebo controlled evaluation of the efficacy and tolerability of Permixon in benign prostatic hyperplasia after exclusion of placebo responders
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0029859371
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PID: 8922564, COI: 1:STN:280:DyaK2s%2FotFeiuw%3D%3D
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Plosker GL, Brogden RN: Serenoa repens (Permixon). A review of its pharmacology and therapeutic efficacy in benign prostatic hyperplasia. Drugs Aging 1996, 9:379–395.
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Br J Urol
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0035667564
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Randomized, double-blind, placebo-controlled trial of saw palmetto in men with lower urinary tract symptoms
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PID: 11744467, COI: 1:STN:280:DC%2BD3MnpvV2ntw%3D%3D, The results of this trial indicated significant improvement urinary symptoms using saw palmetto compared with placebo. No significant change peak urinary flow rate was noted
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Gerber GS, Kuznetsov D, Johnson BC, et al.: Randomized, double-blind, placebo-controlled trial of saw palmetto in men with lower urinary tract symptoms. Urology 2001, 58:960–965. The results of this trial indicated significant improvement in urinary symptoms using saw palmetto compared with placebo. No significant change in peak urinary flow rate was noted. DOI: 10.1016/S0090-4295(01)01442-X
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PID: 9820264, COI: 1:STN:280:DyaK1M%2Fjs1Wmsg%3D%3D, This meta-analysis of close to 3000 men concluded that saw palmetto was superior to placebo relieving urinary symptoms men with BPH. Although this study generated a great deal of coverage the lay press, its findings are somewhat limited by the inclusion of many poorly conducted studies
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Wilt TJ, Ishani A, Stark G, et al.: Saw palmetto extracts for treatment of benign prostatic hyperplasia. A systematic review. JAMA 1998, 280:1604–1609. This meta-analysis of close to 3000 men concluded that saw palmetto was superior to placebo in relieving urinary symptoms in men with BPH. Although this study generated a great deal of coverage in the lay press, its findings are somewhat limited by the inclusion of many poorly conducted studies. DOI: 10.1001/jama.280.18.1604
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85130033712
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Prostatic volume does not correlate with efficacy of treatment for mild to moderate benign prostatic hyperplasia using either finasteride or phytotherapy (Permixon). Paper presented at the 4th International Consultation on BPH. Paris
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COI: 1:STN:280:DyaL2M7kslGmtg%3D%3D, Small study of brief duration that suggested a significant improvement urinary symptoms using Pygeum africanum compared with placebo
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Randomised, placebo-controlled, double-blind clinical trial of beta-sitosterol in patients with benign prostatic hyperplasia
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PID: 1690486, COI: 1:STN:280:DyaK3c7psVGjsg%3D%3D
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Randomized, double blinded placebo controlled trial to evaluate the efficacy of B-sitosterol (Phytosterol) in patients with obstructive and irritative symptoms due to BPH. Paper presented at the 4th International Consultation on BPH. Paris
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