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Volumn 9, Issue 5, 1996, Pages 379-395

Serenoa repens (Permixon®). A review of its pharmacology and therapeutic efficacy in benign prostatic hyperplasia

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; ANDROGEN RECEPTOR; ANDROSTANOLONE; DOXAZOSIN; FINASTERIDE; OXIDOREDUCTASE; TERAZOSIN;

EID: 0029859371     PISSN: 1170229X     EISSN: None     Source Type: Journal    
DOI: 10.2165/00002512-199609050-00008     Document Type: Review
Times cited : (123)

References (86)
  • 2
    • 0029007017 scopus 로고
    • Phytotherapeutic agents in the management of symptomatic benign prostatic hyperplasia
    • Fitzpatrick JM, Lynch TH. Phytotherapeutic agents in the management of symptomatic benign prostatic hyperplasia. Urol Clin North Am 1995; 22 (2): 407-12
    • (1995) Urol Clin North Am , vol.22 , Issue.2 , pp. 407-412
    • Fitzpatrick, J.M.1    Lynch, T.H.2
  • 3
    • 0002649950 scopus 로고
    • The Saw palmetto Serenoa repens: Botanical and chemical aspects
    • Neuzil E, Cousse H. The Saw palmetto Serenoa repens: botanical and chemical aspects. Bull Soc Pharm Bordeaux 1993; 132: 121-41
    • (1993) Bull Soc Pharm Bordeaux , vol.132 , pp. 121-141
    • Neuzil, E.1    Cousse, H.2
  • 4
    • 3543055492 scopus 로고    scopus 로고
    • Permixon®: An overview of its pharmacological activities as regards medical treatment of benign prostatic hypertrophy (BPH)
    • Dimopoulos CA. Di Silverio F, editors. BPH: From molecular biology to patient relief. 1995 Sep 6-10; Rhodes. Bologna: Monduzzi Editore
    • Raynaud J-P. Permixon®: an overview of its pharmacological activities as regards medical treatment of benign prostatic hypertrophy (BPH). In: Dimopoulos CA. Di Silverio F, editors. BPH: From molecular biology to patient relief. Proceedings of the satellite symposium held during the 4th Mediterranean Congress of Urology: 1995 Sep 6-10; Rhodes. Bologna: Monduzzi Editore, 1996: 57-69
    • (1996) Proceedings of the Satellite Symposium Held during the 4th Mediterranean Congress of Urology , pp. 57-69
    • Raynaud, J.-P.1
  • 5
    • 84995906258 scopus 로고
    • Changes in the metabolism of dihydrotestosterone in the hyperplastic human prostate
    • Isaacs JT, Brendler CB, Walsh PC. Changes in the metabolism of dihydrotestosterone in the hyperplastic human prostate. J Clin Endocrinol Metab 1983; 56: 139-46
    • (1983) J Clin Endocrinol Metab , vol.56 , pp. 139-146
    • Isaacs, J.T.1    Brendler, C.B.2    Walsh, P.C.3
  • 6
    • 0026756111 scopus 로고
    • Prostate visualisation studies in male homozygous and heterozygous for 5α-reductase deficiency
    • Imperato-McGinley G, Gautier T, Zirinsky K, et al. Prostate visualisation studies in male homozygous and heterozygous for 5α-reductase deficiency. J Clin Endocrinol Metab 1992; 75: 1022-6
    • (1992) J Clin Endocrinol Metab , vol.75 , pp. 1022-1026
    • Imperato-McGinley, G.1    Gautier, T.2    Zirinsky, K.3
  • 7
    • 0015158376 scopus 로고
    • Comparison of the metabolites found in rat prostate following the in vivo administration of 7 natural androgens
    • Bruchovsky N. Comparison of the metabolites found in rat prostate following the in vivo administration of 7 natural androgens. Endocrinology 1971; 89: 1212-8
    • (1971) Endocrinology , vol.89 , pp. 1212-1218
    • Bruchovsky, N.1
  • 8
    • 0014847075 scopus 로고
    • Dihydrotestosterone of prostatic hypertrophy. 1. The formation and content of dihydrotestosterone in the hypertrophic state of man
    • Sitteree PK, Wilson JD. Dihydrotestosterone of prostatic hypertrophy. 1. The formation and content of dihydrotestosterone in the hypertrophic state of man. J Clin Invest 1970; 49: 1737-45
    • (1970) J Clin Invest , vol.49 , pp. 1737-1745
    • Sitteree, P.K.1    Wilson, J.D.2
  • 9
    • 0021050565 scopus 로고
    • Tissue content of dihydrotestosterone in human prostatic hyperplasia is not supranormal
    • Walsh PC, Hutchins GM, Ewing LL. Tissue content of dihydrotestosterone in human prostatic hyperplasia is not supranormal. J Clin Invest 1983; 72: 1772-7
    • (1983) J Clin Invest , vol.72 , pp. 1772-1777
    • Walsh, P.C.1    Hutchins, G.M.2    Ewing, L.L.3
  • 10
    • 0028301655 scopus 로고
    • Inhibition of the activity of 'basic' 5 α-reductase (type 1) detected in du 145 cells and expressed in insect cells
    • Mar
    • Délos S, Iehlé C, Martin PM, et al. Inhibition of the activity of 'basic' 5 α-reductase (type 1) detected in DU 145 cells and expressed in insect cells. J Steroid Biochem Mol Biol 1994 Mar; 48: 347-52
    • (1994) J Steroid Biochem Mol Biol , vol.48 , pp. 347-352
    • Délos, S.1    Iehlé, C.2    Martin, P.M.3
  • 11
    • 0028825864 scopus 로고
    • Human prostatic steroid 5α-reductase isoforms - A comparative study of selective inhibitors
    • Iehlé C, Délos S, Guirou O, et al. Human prostatic steroid 5α-reductase isoforms - a comparative study of selective inhibitors. J Steroid Biochem Mol Biol 1995; 54: 273-9
    • (1995) J Steroid Biochem Mol Biol , vol.54 , pp. 273-279
    • Iehlé, C.1    Délos, S.2    Guirou, O.3
  • 12
    • 0028050246 scopus 로고
    • Comparison of finasteride (Proscar®) and Serenoa repens (Permixon®) in the inhibition of 5-alpha reductase in healthy male volunteers
    • Strauch G, Perles P, Vergult G, et al. Comparison of finasteride (Proscar®) and Serenoa repens (Permixon®) in the inhibition of 5-alpha reductase in healthy male volunteers. Eur Urol 1994; 26: 247-52
    • (1994) Eur Urol , vol.26 , pp. 247-252
    • Strauch, G.1    Perles, P.2    Vergult, G.3
  • 13
    • 3543108120 scopus 로고
    • A new treatment of prostatic hyperplasia. Permixon® has antiandrogen effects at two complementary levels
    • Briley M, Carilla E, Roger A, et al. A new treatment of prostatic hyperplasia. Permixon® has antiandrogen effects at two complementary levels. New Trends Androlog Sci 1985; 1 (1): 24-6
    • (1985) New Trends Androlog Sci , vol.1 , Issue.1 , pp. 24-26
    • Briley, M.1    Carilla, E.2    Roger, A.3
  • 14
    • 0021245734 scopus 로고
    • Binding of Permixon, a new treatment for prostatic benign hyperplasia, to the cytosolic androgen receptor in the rat prostate
    • Jan
    • Carilla E, Briley M, Fauran F, et al. Binding of Permixon, a new treatment for prostatic benign hyperplasia, to the cytosolic androgen receptor in the rat prostate. J Steroid Biochem 1984 Jan; 20: 521-3
    • (1984) J Steroid Biochem , vol.20 , pp. 521-523
    • Carilla, E.1    Briley, M.2    Fauran, F.3
  • 15
    • 0342998301 scopus 로고
    • The lipido-sterolic extract of Serenoa repens B: New treatment of prostatic hyperplasia. With anti-androgen effects at two complementary levels
    • Carilla E, Roger A, Briley M, et al. The lipido-sterolic extract of Serenoa repens B: new treatment of prostatic hyperplasia. with anti-androgen effects at two complementary levels. Excerpta Medica 1986: 216-23
    • (1986) Excerpta Medica , pp. 216-223
    • Carilla, E.1    Roger, A.2    Briley, M.3
  • 16
    • 0021282157 scopus 로고
    • Inhibition of androgen metabolism and binding by a liposterolic extract of "Serenoa Repens B" in human foreskin fibroblasts
    • Sultan C, Terraza A, Devillier C, et al. Inhibition of androgen metabolism and binding by a liposterolic extract of "Serenoa Repens B" in human foreskin fibroblasts. J Steroid Biochem 1984; 20 (1): 515-9
    • (1984) J Steroid Biochem , vol.20 , Issue.1 , pp. 515-519
    • Sultan, C.1    Terraza, A.2    Devillier, C.3
  • 17
    • 10544245914 scopus 로고
    • Anti-androgenic effects of Permixon: In vitro studies. New trends in BPH etiopathogenesis
    • 1987 Jul 22-25; Cannes, Rome; Acta Medica
    • Sultan C, Terraza A, Carilla E, et al. Anti-androgenic effects of Permixon: in vitro studies. New trends in BPH etiopathogenesis. Proceedings of the International Workshop in Urology; 1987 Jul 22-25; Cannes, Rome; Acta Medica, 1988: 239-246.
    • (1988) Proceedings of the International Workshop in Urology , pp. 239-246
    • Sultan, C.1    Terraza, A.2    Carilla, E.3
  • 18
    • 10544234448 scopus 로고    scopus 로고
    • Permixon®: Antagonist of prolactin (PRL) action on the prostate
    • abstract no. 749. Washington, USA
    • Farnsworth WE, Permixon®: antagonist of prolactin (PRL) action on the prostate [abstract no. 749]. 73rd Annual Meeting of the Endocrine Society, Washington, USA.
    • 73rd Annual Meeting of the Endocrine Society
    • Farnsworth, W.E.1
  • 19
    • 0028862048 scopus 로고
    • The lipidosterolic extract from Serenoa repens interferes with prolactin receptor signal transduction
    • Vacher P, Prevarskaya N, Skryma R, et al. The lipidosterolic extract from Serenoa repens interferes with prolactin receptor signal transduction. J Biomed Sci 1995; 2: 357-65
    • (1995) J Biomed Sci , vol.2 , pp. 357-365
    • Vacher, P.1    Prevarskaya, N.2    Skryma, R.3
  • 22
    • 10544254900 scopus 로고    scopus 로고
    • Anti-inflammatory and antiagregant activities of a lipido-sterolic extract from Serenoa repens on human neutrophiles and on human platelets models
    • Crastes de Paulet A, Dumon M, Le Doucen C, et al. Anti-inflammatory and antiagregant activities of a lipido-sterolic extract from Serenoa repens on human neutrophiles and on human platelets models. Pierre Fabre Médicaments. (Data on file)
    • Pierre Fabre Médicaments. (Data on File)
    • Crastes De Paulet, A.1    Dumon, M.2    Le Doucen, C.3
  • 23
    • 0011787884 scopus 로고
    • Permixon® [lipido sterolic extract of Serenoa repens (LSESr)] inhibits b-FGF- and EGF-induced proliferation of human prostate organotypic cell lines
    • Paubert Braquet M, Janssen DH, Servent N, et al. Permixon® [lipido sterolic extract of Serenoa repens (LSESr)] inhibits b-FGF- and EGF-induced proliferation of human prostate organotypic cell lines [abstract]. Pharmacol Res 1995; 31 Suppl.: 69
    • (1995) Pharmacol Res , vol.31 , Issue.SUPPL. , pp. 69
    • Paubert Braquet, M.1    Janssen, D.H.2    Servent, N.3
  • 24
    • 0013510698 scopus 로고    scopus 로고
    • Response of tissue androgen and epidermal growth factor concentrations to the long-term administration of Serenoa repens (Permixon®), finasteride and flutamide to BPH patients
    • Di Silverio F, Sciarr A, D'Eramo G, et al. Response of tissue androgen and epidermal growth factor concentrations to the long-term administration of Serenoa repens (Permixon®), finasteride and flutamide to BPH patients. Eur Urol 1996; 30 Suppl. 2: 96
    • (1996) Eur Urol , vol.30 , Issue.2 SUPPL. , pp. 96
    • Di Silverio, F.1    Sciarr, A.2    D'Eramo, G.3
  • 25
    • 0020985034 scopus 로고
    • Anti-edematous action of a hexane extract of the stone fruit of Serenoa repens Bartr
    • Tarayre JP, Delhon A, Lauressergues H, et al. Anti-edematous action of a hexane extract of the stone fruit of Serenoa repens Bartr [in French]. Ann Pharm Fr 1983; 41: 559-70
    • (1983) Ann Pharm Fr , vol.41 , pp. 559-570
    • Tarayre, J.P.1    Delhon, A.2    Lauressergues, H.3
  • 26
    • 0026469615 scopus 로고
    • Evidence that Serenoa repens extract displays an antiestrogenic activity in prostatic tissue of benign prostatic hypertrophy
    • Di Silverio F, D'Eramo G, Lubrano C, et al. Evidence that Serenoa repens extract displays an antiestrogenic activity in prostatic tissue of benign prostatic hypertrophy. Eur Urol 1992; 21: 309-14
    • (1992) Eur Urol , vol.21 , pp. 309-314
    • Di Silverio, F.1    D'Eramo, G.2    Lubrano, C.3
  • 27
    • 0027476325 scopus 로고
    • Comparison of finasteride (Proscar®), a 5-α reductase inhibitor, and various commercial plant extracts in in vitro and in vivo 5-α reductase inhibition
    • Rhodes L, Primka RL, Berman C, et al. Comparison of finasteride (Proscar®), a 5-α reductase inhibitor, and various commercial plant extracts in in vitro and in vivo 5-α reductase inhibition. Prostate 1993; 22 (1): 43-51
    • (1993) Prostate , vol.22 , Issue.1 , pp. 43-51
    • Rhodes, L.1    Primka, R.L.2    Berman, C.3
  • 28
    • 0025303307 scopus 로고
    • Structural and biochemical properties of cloned and expressed human and rat steroid 5α-reductases
    • Andersson S, Russell DW. Structural and biochemical properties of cloned and expressed human and rat steroid 5α-reductases. Proc Natl Acad Sci USA 1990; 87: 3640-4
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 3640-3644
    • Andersson, S.1    Russell, D.W.2
  • 29
    • 0026543274 scopus 로고
    • Genetic and pharmacological evidence for more than one human steroid 5α-reductase
    • Jenkins EP, Andersson S, Imperato-McGinley G, et al. Genetic and pharmacological evidence for more than one human steroid 5α-reductase. J Clin Invest 1992; 89: 293-300
    • (1992) J Clin Invest , vol.89 , pp. 293-300
    • Jenkins, E.P.1    Andersson, S.2    Imperato-McGinley, G.3
  • 30
    • 0026055914 scopus 로고
    • Deletion of steroid 5α-reductase 2 gene in male pseudohermaphroditism
    • Andersson S, Berman DM, Jenkins EP, et al. Deletion of steroid 5α-reductase 2 gene in male pseudohermaphroditism. Nature 1991; 354: 159-61
    • (1991) Nature , vol.354 , pp. 159-161
    • Andersson, S.1    Berman, D.M.2    Jenkins, E.P.3
  • 31
    • 0027359618 scopus 로고
    • Benign prostatic hyperplasia in normal prostate aging: Differences in types I and II 5 alpha reductase and steroid hormone receptor messenger ribonucleic acid (mRNA) levels but not in insulin like growth factor mRNA levels
    • Bonnet P, Reiter E, Bruyninx M, et al. Benign prostatic hyperplasia in normal prostate aging: differences in types I and II 5 alpha reductase and steroid hormone receptor messenger ribonucleic acid (mRNA) levels but not in insulin like growth factor mRNA levels. J Clin Endocrinol Metab 1993; 77: 1203-8
    • (1993) J Clin Endocrinol Metab , vol.77 , pp. 1203-1208
    • Bonnet, P.1    Reiter, E.2    Bruyninx, M.3
  • 32
    • 0027177304 scopus 로고
    • LY191704: A selective, nonsteroidal inhibitor of human steroid 5α-reductase type 1
    • Hirsch KS, Jones CD, Audia JE, et al. LY191704: a selective, nonsteroidal inhibitor of human steroid 5α-reductase type 1. Proc Natl Acad Sci USA 1993; 90: 5277-81
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 5277-5281
    • Hirsch, K.S.1    Jones, C.D.2    Audia, J.E.3
  • 33
    • 3543049767 scopus 로고    scopus 로고
    • Steroid 5α-reductase type 1 is expressed in the human pathological prostate
    • May
    • Iehlé C, Raynaud J-P, Martin P-M, et al. Steroid 5α-reductase type 1 is expressed in the human pathological prostate [abstract]. J Urol 1996 May; 155 (5) Suppl.: 808
    • (1996) J Urol , vol.155 , Issue.5 SUPPL. , pp. 808
    • Iehlé, C.1    Raynaud, J.-P.2    Martin, P.-M.3
  • 34
    • 0020558606 scopus 로고
    • Kinetic analysis of 5α-reductase isoenzymes in benign prostatic hyperplasia (BPH)
    • Rennie PS, Bruchovsky N, McLaughlan MG, et al. Kinetic analysis of 5α-reductase isoenzymes in benign prostatic hyperplasia (BPH). J Steroid Biochem 1983; 19: 169-73
    • (1983) J Steroid Biochem , vol.19 , pp. 169-173
    • Rennie, P.S.1    Bruchovsky, N.2    McLaughlan, M.G.3
  • 35
    • 3543083638 scopus 로고    scopus 로고
    • The expression of type 1 and type 2 5-alpha reductase mRNA in BPH and prostate cancer and in short term primary cultures of prostate epithelial and stromal cells
    • 19-20 Mar: The University of York, UK
    • Ross M, Chapman K, Habib FK. The expression of type 1 and type 2 5-alpha reductase mRNA in BPH and prostate cancer and in short term primary cultures of prostate epithelial and stromal cells [abstract]. British Prostate Group: Future Perspectives in Prostatic Disease; 1996; 19-20 Mar: The University of York, UK, p22.
    • (1996) British Prostate Group: Future Perspectives in Prostatic Disease , pp. 22
    • Ross, M.1    Chapman, K.2    Habib, F.K.3
  • 36
    • 0030026298 scopus 로고    scopus 로고
    • Immunohistochemical localization of steroid 5α-reductase 2 in the human male fetal reproductive tract and adult prostate
    • Levine AC, Wang J-P, Ren M, et al. Immunohistochemical localization of steroid 5α-reductase 2 in the human male fetal reproductive tract and adult prostate. J Clin Endocrinol Metab 1996; 81 (1): 384-9
    • (1996) J Clin Endocrinol Metab , vol.81 , Issue.1 , pp. 384-389
    • Levine, A.C.1    Wang, J.-P.2    Ren, M.3
  • 38
    • 0028303201 scopus 로고
    • Expression and regulation of steroid 5α-reductase 2 in prostate disease
    • Silver I, Wiley EL, Davis DL, et al. Expression and regulation of steroid 5α-reductase 2 in prostate disease. J Urol 1994; 152: 433-7
    • (1994) J Urol , vol.152 , pp. 433-437
    • Silver, I.1    Wiley, E.L.2    Davis, D.L.3
  • 39
    • 0028333981 scopus 로고
    • Cell type specific expression of 5α-reductase 2
    • Silver I, Wiley EL, Thigpen AE, et al. Cell type specific expression of 5α-reductase 2. J Urol 1994; 152: 438-42
    • (1994) J Urol , vol.152 , pp. 438-442
    • Silver, I.1    Wiley, E.L.2    Thigpen, A.E.3
  • 40
    • 0027234897 scopus 로고
    • Tissue distribution and ontogeny of steroid 5α-reductase isozyme expression
    • Thigpen AE, Silver RI, Guiteyardo JM, et al. Tissue distribution and ontogeny of steroid 5α-reductase isozyme expression. J Clin Invest 1993; 92: 903-10
    • (1993) J Clin Invest , vol.92 , pp. 903-910
    • Thigpen, A.E.1    Silver, R.I.2    Guiteyardo, J.M.3
  • 41
    • 0001584187 scopus 로고
    • The steroid receptor superfamily: Transactivators of gene expression
    • Parker MG, editor. London: Academic Press
    • Tsai SY, Tsai M-J, O'Malley BW. The steroid receptor superfamily: transactivators of gene expression. In: Parker MG, editor. Nuclear hormone receptors. London: Academic Press, 1991: 103-24
    • (1991) Nuclear Hormone Receptors , pp. 103-124
    • Tsai, S.Y.1    Tsai, M.-J.2    O'Malley, B.W.3
  • 42
    • 10344251011 scopus 로고    scopus 로고
    • Effects of the lipidosterolic extract of Serenoa repens (Permixon®) on human prostatic cell lines
    • In press
    • Ravenna L, Di Silverio F, Russo M, et al. Effects of the lipidosterolic extract of Serenoa repens (Permixon®) on human prostatic cell lines. Prostate. In press
    • Prostate
    • Ravenna, L.1    Di Silverio, F.2    Russo, M.3
  • 43
    • 0023921533 scopus 로고
    • Sex-hormone-induced inflammation and fibromuscular proliferation in the rat lateral prostate
    • Robinette CL. Sex-hormone-induced inflammation and fibromuscular proliferation in the rat lateral prostate. Prostate 1988; 12: 271-86
    • (1988) Prostate , vol.12 , pp. 271-286
    • Robinette, C.L.1
  • 44
    • 0026584617 scopus 로고
    • Phenotypic characterization of infiltrating leukocytes in benign prostatic hyperplasia
    • Theyer G, Kramer G, Assmann I, et al. Phenotypic characterization of infiltrating leukocytes in benign prostatic hyperplasia. Lab Invest 1992; 66: 96-107
    • (1992) Lab Invest , vol.66 , pp. 96-107
    • Theyer, G.1    Kramer, G.2    Assmann, I.3
  • 45
    • 0030240319 scopus 로고    scopus 로고
    • Effect of Serenoa repens extract (Permixon®) on estradiol/testosterone-induced experimental prostate enlargement in the rat
    • In press
    • Paubert-Braquet M, Richardson FO, Servent-Saez N, et al. Effect of Serenoa repens extract (Permixon®) on estradiol/testosterone-induced experimental prostate enlargement in the rat. Pharmacol Res. In press
    • Pharmacol Res
    • Paubert-Braquet, M.1    Richardson, F.O.2    Servent-Saez, N.3
  • 46
    • 0019981578 scopus 로고
    • Pharmacologic and biochemical study of the hexane extract of Serenoa repens B (PA 109)
    • Stenger A, Tarayre J-P, Carilla E, et al. Pharmacologic and biochemical study of the hexane extract of Serenoa repens B (PA 109). La Gazette Médicale de France 1982; 89 (17): 2041-8
    • (1982) La Gazette Médicale de France , vol.89 , Issue.17 , pp. 2041-2048
    • Stenger, A.1    Tarayre, J.-P.2    Carilla, E.3
  • 48
    • 0028887712 scopus 로고
    • Benign prostatic hyperplasia. Medical and minimally invasive treatment options
    • Oesterling JE. Benign prostatic hyperplasia. Medical and minimally invasive treatment options. N Engl J Med 1995; 332 (2): 99-109
    • (1995) N Engl J Med , vol.332 , Issue.2 , pp. 99-109
    • Oesterling, J.E.1
  • 49
    • 0028960321 scopus 로고
    • Therapeutic controversies: Clinical treatment of benign prostatic hyperplasia
    • Geller J, Kirschenbaum A, Lepor H, et al. Therapeutic controversies: clinical treatment of benign prostatic hyperplasia. J Clin Endocrinol Metab 1995; 80 (3): 745-8
    • (1995) J Clin Endocrinol Metab , vol.80 , Issue.3 , pp. 745-748
    • Geller, J.1    Kirschenbaum, A.2    Lepor, H.3
  • 50
    • 0029303348 scopus 로고
    • 1-Blockers vs 5α-reductase inhibitors in benign prostatic hyperplasia: A comparative review
    • 1-Blockers vs 5α-reductase inhibitors in benign prostatic hyperplasia: a comparative review. Drugs Aging 1995; 6 (5): 388-96
    • (1995) Drugs Aging , vol.6 , Issue.5 , pp. 388-396
    • Andersen, J.T.1
  • 51
    • 0021149603 scopus 로고
    • The development of human benign prostatic hyperplasia with age
    • Berry SJ, Coffey DS, Walsh PC, et al. The development of human benign prostatic hyperplasia with age. J Urol 1984; 132: 474-9
    • (1984) J Urol , vol.132 , pp. 474-479
    • Berry, S.J.1    Coffey, D.S.2    Walsh, P.C.3
  • 52
    • 23444457824 scopus 로고
    • Benign prostatic hyperplasia (BPH) - Diagnosis and treatment
    • Apr 20
    • Clinton JJ. Benign prostatic hyperplasia (BPH) - diagnosis and treatment. JAMA 1994 Apr 20; 271: 1151
    • (1994) JAMA , vol.271 , pp. 1151
    • Clinton, J.J.1
  • 53
    • 15844378209 scopus 로고    scopus 로고
    • Treatment of benign prostatic hyperplasia. Reply
    • May 4
    • Lepor H, Nitti VW. Treatment of benign prostatic hyperplasia. Reply [letter]. Lancet 1996 May 4; 347: 1270
    • (1996) Lancet , vol.347 , pp. 1270
    • Lepor, H.1    Nitti, V.W.2
  • 54
    • 0023558276 scopus 로고
    • A multicenter study of the efficacy of Permixon in daily practice
    • Authie D, Cauquil J. A multicenter study of the efficacy of Permixon in daily practice [in French]. C R Ther Pharmacol Clin 1987; 5 (56): 3-13
    • (1987) C R Ther Pharmacol Clin , vol.5 , Issue.56 , pp. 3-13
    • Authie, D.1    Cauquil, J.2
  • 55
    • 10544230029 scopus 로고
    • Efficacy of Permixon® in the treatment of benign prostatic hyperplasia
    • Ebbinghaus KD. Efficacy of Permixon® in the treatment of benign prostatic hyperplasia [in German]. Journal Für Urologie und Urogynäkologie 1995; 2: 17-21
    • (1995) Journal für Urologie und Urogynäkologie , vol.2 , pp. 17-21
    • Ebbinghaus, K.D.1
  • 56
    • 12944255464 scopus 로고
    • Advances in the medical management of benign prostatic hyperplasia
    • Barreto HP, de Vivero C, Castro LEC, et al. Advances in the medical management of benign prostatic hyperplasia [in Spanish]. Tribuna Medica 1995; 91 (4): 197-205
    • (1995) Tribuna Medica , vol.91 , Issue.4 , pp. 197-205
    • Barreto, H.P.1    De Vivero, C.2    Castro, L.E.C.3
  • 57
    • 0027546207 scopus 로고
    • Alternative treatment of benign prostatic hypertrophy by Permixon (Capistan)
    • Feb
    • Hanus M, Matouskova M. Alternative treatment of benign prostatic hypertrophy by Permixon (Capistan) [in Czech]. Rozhl Chir 1993 Feb; 72: 75-9
    • (1993) Rozhl Chir , vol.72 , pp. 75-79
    • Hanus, M.1    Matouskova, M.2
  • 58
    • 0022939083 scopus 로고
    • Serenoa repens in treatment of benign prostate hypertrophy
    • Mancuso G, Guillot F, Migaleddu V, et al. Serenoa repens in treatment of benign prostate hypertrophy [in Italian]. Urologia 1986; 53 (5): 709-14
    • (1986) Urologia , vol.53 , Issue.5 , pp. 709-714
    • Mancuso, G.1    Guillot, F.2    Migaleddu, V.3
  • 59
    • 0022937783 scopus 로고
    • Treatment of prostate adenoma with Serenoa repens extract
    • Martorana G, Giberti C, Pizzorno R, et al. Treatment of prostate adenoma with Serenoa repens extract [in Italian]. Urologia 1986; 53 (3): 366-9
    • (1986) Urologia , vol.53 , Issue.3 , pp. 366-369
    • Martorana, G.1    Giberti, C.2    Pizzorno, R.3
  • 60
    • 0023574152 scopus 로고
    • Our experience with a hexane extract of Serenoa repens in the treatment of benign prostatic hypertrophy
    • Jun
    • Olle-Carreras J. Our experience with a hexane extract of Serenoa repens in the treatment of benign prostatic hypertrophy [in Spanish]. Arch Esp Urol 1987 Jun; 40: 310-3
    • (1987) Arch Esp Urol , vol.40 , pp. 310-313
    • Olle-Carreras, J.1
  • 61
    • 0024256004 scopus 로고
    • Clinical and flowmetric study of Permixon in aged patients
    • Orfei S, Grumelli B, Galetti G. Clinical and flowmetric study of Permixon in aged patients [in Italian]. Urologia 1988; 55 (4): 373-81
    • (1988) Urologia , vol.55 , Issue.4 , pp. 373-381
    • Orfei, S.1    Grumelli, B.2    Galetti, G.3
  • 62
    • 0023028514 scopus 로고
    • Medical treatment of prostate hypertrophy: Trial with the therapeutic use of Serenoa repens
    • Paoletti PP, Francalanci R, Tenti S, et al. Medical treatment of prostate hypertrophy: trial with the therapeutic use of Serenoa repens [Italian]. Urologia 1986; 53 (2): 182-7
    • (1986) Urologia , vol.53 , Issue.2 , pp. 182-187
    • Paoletti, P.P.1    Francalanci, R.2    Tenti, S.3
  • 63
    • 0022952653 scopus 로고
    • Urodynamic evaluation of management of prostatic adenoma with Serenoa repens extracl
    • Pescatore D, Calvi P, Michelotti P. Urodynamic evaluation of management of prostatic adenoma with Serenoa repens extracl [in Italian]. Urologia 1986; 53 (6): 894-7
    • (1986) Urologia , vol.53 , Issue.6 , pp. 894-897
    • Pescatore, D.1    Calvi, P.2    Michelotti, P.3
  • 64
    • 0344040436 scopus 로고
    • National experience on therapeutic use of Serenoa repens
    • Pisani E. National experience on therapeutic use of Serenoa repens. New Trends Androlog Sci 1985; 1 (1): 110-2
    • (1985) New Trends Androlog Sci , vol.1 , Issue.1 , pp. 110-112
    • Pisani, E.1
  • 65
    • 10544245456 scopus 로고
    • Mechanism of action of Serenoa repens: Considerations and conclusions
    • Tenaglia R, D'Eramo G, Bertolizzi L, et al. Mechanism of action of Serenoa repens: considerations and conclusions. New Trends Androlog Sci 1985; 1 (1): 132-4
    • (1985) New Trends Androlog Sci , vol.1 , Issue.1 , pp. 132-134
    • Tenaglia, R.1    D'Eramo, G.2    Bertolizzi, L.3
  • 66
    • 0023553215 scopus 로고
    • Treatment of benign prostatic hypertrophy with Serenoa repens
    • Vespasiani G, Cesaroni M, Parziani S, et al. Treatment of benign prostatic hypertrophy with Serenoa repens [in Italian]. Urologia 1987; 54 (2): 145-9
    • (1987) Urologia , vol.54 , Issue.2 , pp. 145-149
    • Vespasiani, G.1    Cesaroni, M.2    Parziani, S.3
  • 67
    • 0026012203 scopus 로고
    • Phytotherapy of benign prostate hyperplasia with Serenoa repens extract (Permixon registered )
    • Dathe G, Schmid H. Phytotherapy of benign prostate hyperplasia with Serenoa repens extract (Permixon registered ) [in German]. Urologe Ausg B 1991; 31 (5): 220-3
    • (1991) Urologe Ausg B , vol.31 , Issue.5 , pp. 220-223
    • Dathe, G.1    Schmid, H.2
  • 68
    • 0343607193 scopus 로고
    • Comparison of Serenoa repens extract and placebo in controlled clinical trial in patients with prostatic adenomatosis
    • Boccafoschi C, Annoscia S. Comparison of Serenoa repens extract and placebo in controlled clinical trial in patients with prostatic adenomatosis [in Italian]. Urologia 1983; 50 (6): 1-14
    • (1983) Urologia , vol.50 , Issue.6 , pp. 1-14
    • Boccafoschi, C.1    Annoscia, S.2
  • 69
    • 0021213498 scopus 로고
    • A double-blind trial of an extract of the plant Screnoa repens in benign prostatic hyperplasia
    • Sep
    • Champault G, Patel JC, Bonnard AM. A double-blind trial of an extract of the plant Screnoa repens in benign prostatic hyperplasia. Br J Clin Pharmacol 1984 Sep; 18: 461-2
    • (1984) Br J Clin Pharmacol , vol.18 , pp. 461-462
    • Champault, G.1    Patel, J.C.2    Bonnard, A.M.3
  • 70
    • 0021931864 scopus 로고
    • Serenoa repens extract vs. placebo
    • Cukier, Ducassou, Le Guillou, et al. Serenoa repens extract vs. placebo. CR Ther Pharmacol Clin 1985; 4 (25): 15-21
    • (1985) CR Ther Pharmacol Clin , vol.4 , Issue.25 , pp. 15-21
    • Cukier1    Ducassou2    Le Guillou3
  • 71
    • 0029066391 scopus 로고
    • Placebo-controlled evaluation of the efficacy and tolerability of Permixon® in benign prostatic hyperplasia after exclusion of placebo responders
    • May
    • Descotes JL, Rambeaud JJ, Deschaseaux P, et al. Placebo-controlled evaluation of the efficacy and tolerability of Permixon® in benign prostatic hyperplasia after exclusion of placebo responders. Clin Drug Invest 1995 May; 9: 291-7
    • (1995) Clin Drug Invest , vol.9 , pp. 291-297
    • Descotes, J.L.1    Rambeaud, J.J.2    Deschaseaux, P.3
  • 72
    • 0000900975 scopus 로고
    • Clinical results on a new drug in the treatment of benign prostatic hyperplasia (Permixon)
    • Emili E, Lo Cigno M, Petrone U. Clinical results on a new drug in the treatment of benign prostatic hyperplasia (Permixon) [in Italian]. Urologia 1983; 50 (5): 1042-9
    • (1983) Urologia , vol.50 , Issue.5 , pp. 1042-1049
    • Emili, E.1    Lo Cigno, M.2    Petrone, U.3
  • 73
    • 0022621170 scopus 로고
    • The value of Permixon in benign prostatic hypertrophy
    • Feb
    • Reece Smith H, Memon A, Smart CJ, et al. The value of Permixon in benign prostatic hypertrophy, Br J Urol 1986 Feb; 58: 36-40
    • (1986) Br J Urol , vol.58 , pp. 36-40
    • Reece Smith, H.1    Memon, A.2    Smart, C.J.3
  • 74
    • 0021794026 scopus 로고
    • Treatment of obstruction in prostatic adenoma using an extract of Serenoa repens. Double-blind clinical test v. placebo
    • Tasca A, Barulli M, Cavazzana A, et al. Treatment of obstruction in prostatic adenoma using an extract of Serenoa repens. Double-blind clinical test v. placebo [in Italian]. Minerva Urol Nefrol 1985; 37 (1): 87-91
    • (1985) Minerva Urol Nefrol , vol.37 , Issue.1 , pp. 87-91
    • Tasca, A.1    Barulli, M.2    Cavazzana, A.3
  • 75
    • 0347318854 scopus 로고    scopus 로고
    • Comparison of phytotherapy (Permixon®) with finasteride in the treatment of benign prostate hyperplasia: A randomized international study of 1098 patients
    • In press
    • Carraro J-C, Raynaud J-P, Koch G, et al. Comparison of phytotherapy (Permixon®) with finasteride in the treatment of benign prostate hyperplasia: a randomized international study of 1098 patients. Prostate. In press
    • Prostate
    • Carraro, J.-C.1    Raynaud, J.-P.2    Koch, G.3
  • 76
    • 0029206194 scopus 로고
    • Comparative effects of alfuzosin versus Serenoa repens in the treatment of symptomatic benign prostatic hyperplasia
    • Jan-Feb
    • Grasso M, Montesano A, Buonaguidi A, et al. Comparative effects of alfuzosin versus Serenoa repens in the treatment of symptomatic benign prostatic hyperplasia. Arch Esp Urol 1995 Jan-Feb; 48: 97-103
    • (1995) Arch Esp Urol , vol.48 , pp. 97-103
    • Grasso, M.1    Montesano, A.2    Buonaguidi, A.3
  • 77
    • 0026841034 scopus 로고
    • Symptomatic treatment of benign hypertrophy of the prostate. Comparative study of prazosin and Serenoa repens
    • Apr
    • Adriazola Semino M, Lozano Ortega JL, Garcia Coho E, et al. Symptomatic treatment of benign hypertrophy of the prostate. Comparative study of prazosin and Serenoa repens [in Spanish]. Arch Esp Urol 1992 Apr; 45: 211-3
    • (1992) Arch Esp Urol , vol.45 , pp. 211-213
    • Adriazola Semino, M.1    Lozano Ortega, J.L.2    Garcia Coho, E.3
  • 78
    • 0020962947 scopus 로고
    • Medical treatment of benign prostatic hyperplasia: Efficacy of the extract of Serenoa repens (Permixon®) compared to that of the extract of Pygeum africanum and a placebo
    • Mandressi S, Tarallo U, Maggioni A. et al. Medical treatment of benign prostatic hyperplasia: efficacy of the extract of Serenoa repens (Permixon®) compared to that of the extract of Pygeum africanum and a placebo [in Italian]. Urologia 1983; 50 (4): 752-8
    • (1983) Urologia , vol.50 , Issue.4 , pp. 752-758
    • Mandressi, S.1    Tarallo, U.2    Maggioni, A.3
  • 79
    • 0022947536 scopus 로고
    • Serenoa repens vs. gestonorone caproate in treatment of benign prostatic hypertrophy
    • Pannunzio E, D'Ascenzo R, Giardinetti F, et al. Serenoa repens vs. gestonorone caproate in treatment of benign prostatic hypertrophy [in Italian]. Urologia 1986; 53 (5): 696-705
    • (1986) Urologia , vol.53 , Issue.5 , pp. 696-705
    • Pannunzio, E.1    D'Ascenzo, R.2    Giardinetti, F.3
  • 80
    • 0027214631 scopus 로고
    • Finasteride: A review of its potential in the treatment of benign prostatic hyperplasia
    • Peters DH, Sorkin EM, Finasteride: a review of its potential in the treatment of benign prostatic hyperplasia. Drugs 1993; 46 (1): 177-208
    • (1993) Drugs , vol.46 , Issue.1 , pp. 177-208
    • Peters, D.H.1    Sorkin, E.M.2
  • 81
    • 0028470989 scopus 로고
    • Benign prostatic hyperplasia: Diagnosis and treatment: guideline overview
    • Jul
    • Anon. Benign prostatic hyperplasia: diagnosis and treatment: guideline overview. J Natl Med Assoc 1994 Jul; 86: 489-549
    • (1994) J Natl Med Assoc , vol.86 , pp. 489-549
  • 82
    • 10544252089 scopus 로고
    • BPH guidelines
    • Feb 19
    • McCarthy M. BPH guidelines. Lancet 1994 Feb 19; 343: 473
    • (1994) Lancet , vol.343 , pp. 473
    • McCarthy, M.1
  • 83
    • 0029143731 scopus 로고
    • α-Blockade in the treatment of symptomatic benign prostatic hyperplasia
    • Eri LM, Tveter KJ. α-Blockade in the treatment of symptomatic benign prostatic hyperplasia. J Urol 1995; 154: 923-34
    • (1995) J Urol , vol.154 , pp. 923-934
    • Eri, L.M.1    Tveter, K.J.2
  • 84
    • 0029115426 scopus 로고
    • Benign prostatic hyperplasia: Pathophysiology and pharmacological treatment
    • Madsen FA, Bruskewitz RC. Benign prostatic hyperplasia: pathophysiology and pharmacological treatment. Curr Opin Nephrol Hypertension 1995; 4: 455-9
    • (1995) Curr Opin Nephrol Hypertension , vol.4 , pp. 455-459
    • Madsen, F.A.1    Bruskewitz, R.C.2
  • 85
    • 9444268678 scopus 로고    scopus 로고
    • The efficacy of terazosin, finasteride, or both in benign prostatic hyperplasia
    • Lepor H, Williford WO, Barry MJ, et al. The efficacy of terazosin, finasteride, or both in benign prostatic hyperplasia. N Engl J Med 1996; 335 (8): 533-9
    • (1996) N Engl J Med , vol.335 , Issue.8 , pp. 533-539
    • Lepor, H.1    Williford, W.O.2    Barry, M.J.3
  • 86
    • 0029742798 scopus 로고    scopus 로고
    • Treatment of benign prostatic hyperplasia
    • Walsh PC. Treatment of benign prostatic hyperplasia [editorial]. N Engl J Med 1996; 335 (8): 586-7
    • (1996) N Engl J Med , vol.335 , Issue.8 , pp. 586-587
    • Walsh, P.C.1


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