The hydrolysis of bimatoprost in corneal tissue generates a potent prostanoid FP receptor agonist

Survey of Ophthalmology

Volumn 47, Issue 4 SUPPL. 1, 2002, Pages

  Maxey, Kirk M ^a   Johnson, Jennifer L ^a   LaBrecque, Jennifer ^a  

^a Cayman Chemical Company   (United States)

Author keywords

Bimatoprost; Cornea; FP receptor; Glaucoma; Hydrolysis; Prostaglandin

Indexed keywords

17 PHENYL 18,19,20 TRINORPROSTAGLANDIN F 2ALPHA; AMIDASE; BIMATOPROST; DRUG METABOLITE; LATANOPROST; PROSTAGLANDIN RECEPTOR STIMULATING AGENT; TRAVOPROST; UNCLASSIFIED DRUG; UNOPROSTONE ISOPROPYL ESTER;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORNEA; DRUG HYDROLYSIS; DRUG TISSUE LEVEL; ENZYME ACTIVITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; INTRAOCULAR PRESSURE; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL;

AMIDES; ANIMALS; ANTIHYPERTENSIVE AGENTS; CATTLE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, THIN LAYER; CORNEA; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; HYDROLYSIS; LIPID METABOLISM; LIPIDS; RECEPTORS, PROSTAGLANDIN; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0036669701     PISSN: 00396257     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0039-6257(02)00323-5     Document Type: Article

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