STAT5 binding contributes to lactational stimulation of promoter III expressing the bovine acetyl-CoA carboxylase α-encoding gene in the mammary gland

Journal of Molecular Endocrinology

Volumn 29, Issue 1, 2002, Pages 73-88

  Mao, J ^a   Molenaar, A J ^a   Wheeler, T T ^a   Seyfert, H M ^a  

^a LEIBNIZ INSTITUTE FOR FARM ANIMAL BIOLOGY FBN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; DEXAMETHASONE; FATTY ACID; LUCIFERASE; NUCLEAR PROTEIN; PROLACTIN; RIBONUCLEASE; STAT5 PROTEIN; DNA; DNA BINDING PROTEIN; MILK PROTEIN; STAT5A PROTEIN, MOUSE; TRANSACTIVATOR PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; BINDING SITE; BREAST EPITHELIUM; COMPLEX FORMATION; CONTROLLED STUDY; COW; ENZYME ASSAY; EPITHELIUM CELL; FATTY ACID SYNTHESIS; FEMALE; GENE EXPRESSION; GENE INACTIVATION; GENETIC CODE; GENETIC TRANSFECTION; IN SITU HYBRIDIZATION; INHIBITION KINETICS; LACTATION; MAMMARY GLAND; MILK; MILK PRODUCTION; NONHUMAN; NUCLEOTIDE SEQUENCE; OLIGONUCLEOTIDE PROBE; POINT MUTATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN SYNTHESIS; QUANTITATIVE ANALYSIS; REPORTER GENE; REVIEW; SIGNAL TRANSDUCTION; ANIMAL; ARTICLE; CATTLE; ENZYMOLOGY; EXON; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOLECULAR GENETICS; MOUSE; PHYSIOLOGY; SITE DIRECTED MUTAGENESIS; UDDER;

ACETYL-COA CARBOXYLASE; ANIMAL; BASE SEQUENCE; CATTLE; DNA; DNA-BINDING PROTEINS; EXONS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; LACTATION; MAMMAE; MICE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROLACTIN; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; SUPPORT, NON-U.S. GOV'T; TRANS-ACTIVATORS; ANIMALS; MAMMARY GLANDS, ANIMAL; MILK PROTEINS; STAT5 TRANSCRIPTION FACTOR;

EID: 0036668570     PISSN: 09525041     EISSN: None     Source Type: Journal    
DOI: 10.1677/jme.0.0290073     Document Type: Review

References (59)

1. Obese gene expression alters the ability of 30A5 preadipocytes to respond to lipogenic hormones
2. Prolactin regulation of β-casein gene expression and of a cytosolic 120 KD protein in a cloned mouse mammary epithelial cell line
3. Eludication of a promoter activity that directs the expression of acetyl-CoA carboxylase a with an alternative N-terminus in a tissue-restricted fashion
4. Characterization of Stat5a and Stat5b homodimers and heterodimers and their association with the glucocortiocoid receptor in mammary cells
5. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease
6. Human Genetics '99: Sexual development; STAT5 signaling in sexually dimorphic gene expression and growth patterns
7. Genetic and phenotypic parameters for 305-day yield, fertility, and survival in Holsteins
8. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
9. 'Touchdown' PCR to prevent spurious priming during gene amplification
10. Prolactin and glucocorticoid hormones synergistically induce expression of transfected rat β-casein gene promoter constructs in mammary epithelial cell line
11. DNA binding specificity of different STAT proteins. Comparison of in vitro specificity with natural target sites
12. Cloning and characterization of the 5′ end and promoter region of the chicken acetyl-CoA carboxylase gene
13. Prolactin, growth hormone, and epidermal growth factor activate Stat5 in different compartments of mammary tissue and exert different and overlapping developmental effects
14. RNA protection assay
15. Prolactin induces phosphorylation of Tyr694 of Stat5 (MGF), a prerequisite for DNA binding and induction of transcription
16. Prolactin, growth hormone, erythropoietin and granulocyte-macrophage colony stimulating factor induce MGF-Stat5 DNA binding activity
17. Understanding adipocyte differentiation
18. Prolactin-mediated transcriptional and posttranscriptional control of casein gene expression
19. Cloning of human acetyl-CoA carboxylase cDNA
20. Regulation of fatty acid synthesis via phosphorylation of acetyl-CoA carboxylase
21. Heritability of milk casein and genetic and phenotypic correlations with production traits
22. Structural deviations in a bovine low expression lysozyme-encoding gene active in tissues other than stomach
23. Prolactin signaling in mammary gland development
24. Nutritional and hormonal regulation of lipogenic-enzyme expression in rat liver
25. Regulation of mammalian acetyl-Coenzyme A carboxylase
26. Promoter-dependent synergy between glucocorticoid receptor and Stat5 in the activation of β-casein gene transcription
27. Pretreatment with glucocorticoid is essential for lactogenic induction of the bovine β-casein/CAT expression in HC11 cells
28. Cloning and expression of Stat5 and an additional homologue (Stat5b) involved in prolactin signal transduction in mouse mammary tissue
29. Stat5a is mandatory for adult mammary gland development and lactogenesis
30. Characterization of different forms of rat mammary gland acetyl-coenzyme A carboxylase mRNA: Analysis of heterogeniety in the 5′ end
31. In vivo regulation of the activity of the two promoters of the rat acetyl coenzyme-A carboxylase gene
32. An enhancer element in the house-keeping promoter for acetyl-CoA carboxylase gene
33. Genomic distribution of three promoters of the bovine gene encoding acetyl-CoA carboxylase alpha and evidence that the nutritionally regulated promoter I contains a repressive element different from that in rat
34. Promoter II of the bovine acetyl-coenzyme A carboxylase-α-encoding gene is widely expressed and strongly active in different cells
35. Expression of α-lactalbumin, α-S1-casein, and lactoferrin genes is heterogenous in sheep and cattle mammary tissue
36. Regulation of milk lipid secretion and composition
37. Lipid synthesis and secretion by primary cultures of rat mammary epithelial cells
38. Multihormonal regulation of casein gene expression at the transcriptional and posttranscriptional levels in the mammary gland
39. Regulation of milk protein gene
40. Components of a Stat recognition code: Evidence for two layers of molecular specificity
41. Mammary gland-specific nuclear factor activity is positively regulated by lactogenic hormones and negatively by milk stasis
42. Regulation of signal transducers and activators of transcription (STATs) by effectors of adipose: Coordinate regulation of STATs1, 5A, and 5B with peroxisome proliferator-activated receptor-γ and C/AAAT enhancer binding protein-α
43. Functional interactions between Stat5 and the glucocorticoid receptor
44. Regulation of acetyl-coenzyme A carboxylase. II. Effect of fasting and refeeding on the activity, phosphate content, and aggregation state of the enzyme
45. Tissue specific expression of the acetyl-CoA carboxylase gene
46. Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice
47. Prolactin: Transport, function, and receptors in mammary gland development and differentiation
48. Regulation of development of the normal mammary gland by hormones and growth factors
49. Hormonal regulation of milk protein gene expression
50. Mammary gland factor (MGF) is a novel member of the cytokine regulated transcription factor gene family and confers the prolactin response
51. Fatty acid synthesis and its regulation
52. Prolactin signal transduction mechanisms in the mammary gland: The role of the Jak/Stat pathway
53. Prolactin-dependent activation of a tyrosine phosphorylated DNA binding factor in mouse mammary epithelial cells
54. Mammary Stat5 abundance and activity are not altered with lactation state in cows
55. A distal enhancer region in the human beta-casein gene mediates the response to prolactin and glucocorticoid hormones
56. Glucocorticoid receptor/signal transducer and activator of transcription 5 (STAT5) interactions enhance STAT5 activation by prolonging STAT5 DNA binding and tyrosine phosphorylation
57. Thyroid hormone, glucagon, and medium-chain fatty acids regulate transcription initiated from promoter 1 and promoter 2 of the acetyl-CoA carboxylase-alpha gene in chick embryo hepatocytes
58. Thyroid hormone stimulates acetyl-coA carboxylase-alpha transcription in hepatocytes by modulating the composition of nuclear receptor complexes bound to thyroid hormone response element
59. Cross-talk between Janus Kinase-Signal Transducer and Activator of Transcription (JAK-STAT) and Peroxisome Proliferator-activated receptor-a (PPARα) signaling pathways