Myocardial effects of ethanol consumption in the rat with streptozotocin-induced diabetes

Alcoholism: Clinical and Experimental Research

Volumn 26, Issue 8, 2002, Pages 1128-1133

  Giles, Thomas D ^a,b   Given, Michael B ^a   Greenberg, Stan S ^a   Zhao, Xinfang ^a   Kerut, Edmund Kenneth ^a   McElwain, Elizabeth ^a   Allen, Gayle ^a  

^a LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b LOUISIANA STATE UNIV MEDICAL CENTER   (United States)

Author keywords

Diabetes mellitus; Ethanol; Myocardium; Protein kinase C

Indexed keywords

ALCOHOL; MEMBRANE PROTEIN; PROTEIN KINASE C ALPHA; PROTEIN KINASE C DELTA; PROTEIN KINASE C EPSILON; ISOENZYME; PROTEIN KINASE C;

ALCOHOL BLOOD LEVEL; ALCOHOL CONSUMPTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVITY; HEART FUNCTION; HEART LEFT VENTRICLE DP-DT; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART LEFT VENTRICLE PRESSURE; HEART PROTECTION; HEART VENTRICLE REMODELING; M MODE ECHOCARDIOGRAPHY; MALE; MEAN ARTERIAL PRESSURE; MYOCARDIAL DISEASE; NONHUMAN; PRIORITY JOURNAL; RAT; STREPTOZOCIN DIABETES; ANIMAL; BLOOD; CARDIOMYOPATHY; CHEMICALLY INDUCED DISORDER; COMPARATIVE STUDY; DISEASE MODEL; DRINKING BEHAVIOR; DRUG EFFECT; ENZYME ACTIVATION; ENZYMOLOGY; EXPERIMENTAL DIABETES MELLITUS; HEART FUNCTION TEST; HEMODYNAMICS; METABOLISM; PATHOPHYSIOLOGY; SPRAGUE DAWLEY RAT;

ANIMALIA;

ALCOHOL DRINKING; ANIMALS; CARDIOMYOPATHIES; DIABETES MELLITUS, EXPERIMENTAL; DISEASE MODELS, ANIMAL; ENZYME ACTIVATION; ETHANOL; HEART FUNCTION TESTS; HEMODYNAMIC PROCESSES; ISOENZYMES; MALE; PROTEIN KINASE C; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0036667825     PISSN: 01456008     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1530-0277.2002.tb02648.x     Document Type: Article

References (32)

1. Idiopathic heart disease. 1. Analysis of 100 cases, with special reference to chronic alcoholism
2. Inotropic effects of ethanol on the isolated papillary muscle of the diabetic rat
3. Association of diabetes mellitus with coronary atherosclerosis and myocardial lesions. An autopsy study from the Honolulu Heart Program
4. Alcohol and diabetes. A position paper prepared by the Nutrition Subcommittee of the British Diabetic Association's Medical Advisory Committee and approved by the Executive Council of the British Diabetic Association
5. Prognosis of diabetics with diabetes onset before the age of thirty-one: I and II
6. Cellular and molecular neuroscience of alcoholism
7. Light-to-moderate alcohol intake is associated with enhanced insulin sensitivity
8. Morbidity and mortality in diabetics in the Framingham population
9. Protein kinase C in early cardiomyopathy in the BB/Wor diabetic rat
10. Preservation of left ventricular function and coronary flow by angiotensin I-converting enzyme inhibition in the hypertensive-diabetic Dahl rat
11. Protein kinase C isozymes in skeletal muscles during the early stage of genetic and streptozocin diabetes
12. ESBRA 1994 Award Lecture. Phosphatidylethanol formation: Specific effects of ethanol mediated via phospholipase D
13. Role of diabetes in congestive heart failure: The Framingham Study
14. Alcohol consumption and diabetes mellitus mortality in different countries
15. Alcohol and mortality
16. Alcohol intake and insulin levels: The Normative Aging Study
17. Activation of protein kinase C by elevation of glucose concentration: Proposal for a mechanism in the development of diabetic vascular complications
18. Serial echocardiographic-Doppler assessment of left ventricular geometry and function in rats with pressure-overload hypertrophy: Chronic angiotensin-converting enzyme inhibition attenuates the transition to heart failure
19. Experimental diabetes is associated with functional activation of protein kinase C epsilon and phosphorylation of troponin I in the heart, which are prevented by angiotensin II receptor blockade
20. Primary myocardial disease. Report of fifty cases and review of the subject
21. Alcohol and diabetes
22. Alcohol and the heart. The long-term effects of alcohol on the cardiovascular system
23. Protein kinase C and lipid signaling for sustained cellular responses
24. Alteration of 1,2-diacylglycerol content in myocardium from diabetic rats
25. Alcoholic cardiomyopathy
26. Diabetes as an atherogenic factor
27. The heart in chronic alcoholism. Clinical and pathological findings
28. 2+ channels in Xenopus oocytes by protein kinase C
29. Alcohol and atherosclerosis
30. Alcohol consumption and risk of coronary heart disease among men with type 2 diabetes mellitus
31. Alcohol intake and the risk of coronary heart disease mortality in persons with older-onset diabetes mellitus
32. Characterization of the mechanism for the chronic activation of diacylglycerol protein kinase C pathway in diabetes and hypergalactosemia