메뉴 건너뛰기




Volumn 3, Issue 7, 2002, Pages 1024-1028

Aldosterone antagonists in congestive heart failure

Author keywords

Aldosterone; Heart failure; Renin angiotensin; Spironolactone

Indexed keywords

ALDOSTERONE; ALDOSTERONE ANTAGONIST; ANGIOTENSIN; CANRENONE; CAPTOPRIL; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENALAPRIL; EPLERENONE; GLUCOCORTICOID RECEPTOR; LOOP DIURETIC AGENT; MINERALOCORTICOID RECEPTOR; POTASSIUM ION; SPIRONOLACTONE; THIAZIDE DIURETIC AGENT;

EID: 0036667099     PISSN: 14724472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (11)

References (39)
  • 1
    • 0033517302 scopus 로고    scopus 로고
    • The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators
    • note
    • Pitt B, Zannad F, Remme WJ, Cody R, Castaigne A, Perez A, Palensky J, Wittes J: The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators. N Engl J Med (1999) 341:709-717. The RALES trial: A landmark study highlighting the salutary effect of aldosterone antagonists in congestive heart failure.
    • (1999) N Engl J Med , vol.341 , pp. 709-717
    • Pitt, B.1    Zannad, F.2    Remme, W.J.3    Cody, R.4    Castaigne, A.5    Perez, A.6    Palensky, J.7    Wittes, J.8
  • 3
    • 0000180160 scopus 로고
    • The physiology of congestive heart failure
    • Hamilton WF (Ed), American Physiological Society, Washington, DC, USA
    • Davis JO: The physiology of congestive heart failure. In: Handbook of Physiology; Section 2: Circulation, vol III Hamilton WF (Ed), American Physiological Society, Washington, DC, USA (1965):2071-2122
    • (1965) Handbook of Physiology; Section 2: Circulation , vol.3 , pp. 2071-2122
    • Davis, J.O.1
  • 4
    • 0031877532 scopus 로고    scopus 로고
    • Current and novel pharmacological approaches in advanced heart failure
    • O'Connor CM, Gattis WA, Swedberg K: Current and novel pharmacological approaches in advanced heart failure. Am Heart J (1998) 135:S249-S263.
    • (1998) Am Heart J , vol.135
    • O'Connor, C.M.1    Gattis, W.A.2    Swedberg, K.3
  • 5
    • 0030870613 scopus 로고    scopus 로고
    • Aldosterone blockade reduces vascular collagen turnover, improves heart rate variability and reduces early morning rise in heart rate in heart failure patients
    • note
    • MacFadyen RJ, Barr CS, Struthers AD: Aldosterone blockade reduces vascular collagen turnover, improves heart rate variability and reduces early morning rise in heart rate in heart failure patients. Cardiovasc Res (1997) 35:30-34. The first study to demonstrate the effect of spironolactone on both heart rate variability and markers of myocardial fibrosis in patients with congestive heart failure.
    • (1997) Cardiovasc Res , vol.35 , pp. 30-34
    • MacFadyen, R.J.1    Barr, C.S.2    Struthers, A.D.3
  • 6
    • 0027465156 scopus 로고
    • Angiotensin-converting enzyme inhibitor and spironolactone combination therapy. New objectives in congestive heart failure treatment
    • note
    • Zannad F: Angiotensin-converting enzyme inhibitor and spironolactone combination therapy. New objectives in congestive heart failure treatment. Am J Cardiol (1993) 71:34A-39A. A review article with comprehensive references discussing the effects of the interaction of spironolactone and ACE inhibitors on the pathophysiology of congestive heart failure.
    • (1993) Am J Cardiol , vol.71
    • Zannad, F.1
  • 7
    • 0034169037 scopus 로고    scopus 로고
    • Recent advances in cardiovascular pharmacology
    • Frishman WH: Recent advances in cardiovascular pharmacology. Curr Probl Cardiol (2000) 25:227-295.
    • (2000) Curr Probl Cardiol , vol.25 , pp. 227-295
    • Frishman, W.H.1
  • 8
    • 0003984768 scopus 로고    scopus 로고
    • Medical Economics Company, Montvale, NJ, USA
    • Physicians' Desk Reference, 53rd Ed. Medical Economics Company, Montvale, NJ, USA (1999).
    • (1999) Physicians' Desk Reference, 53rd Ed.
  • 9
    • 0018751617 scopus 로고
    • Canrenoate - A spironolactone metabolite. Acute cardiac effects in digitalized patients
    • note
    • Waldorff S, Buch J: Canrenoate - A spironolactone metabolite. Acute cardiac effects in digitalized patients. Eur J Cardiol (1979) 10:143-149. A study of the effects of canrenoate on ventricular function.
    • (1979) Eur J Cardiol , vol.10 , pp. 143-149
    • Waldorff, S.1    Buch, J.2
  • 10
    • 0002700941 scopus 로고    scopus 로고
    • Epleronone (SC 66110), a highly selective aldosterone antagonist
    • Delyani J, Myles M, Funder J: Epleronone (SC 66110), a highly selective aldosterone antagonist. Am J Hypertens (1998) 11:94A.
    • (1998) Am J Hypertens , vol.11
    • Delyani, J.1    Myles, M.2    Funder, J.3
  • 11
    • 0025088737 scopus 로고
    • Hormones regulating cardiovascular function in patients with severe congestive heart failure and their relation to mortality. CONSENSUS Trial Study Group
    • Swedberg K, Eneroth P, Kjekshus J, Wilhelmsen L: Hormones regulating cardiovascular function in patients with severe congestive heart failure and their relation to mortality. CONSENSUS Trial Study Group. Circulation (1990) 82:1730-1736.
    • (1990) Circulation , vol.82 , pp. 1730-1736
    • Swedberg, K.1    Eneroth, P.2    Kjekshus, J.3    Wilhelmsen, L.4
  • 12
    • 0027405741 scopus 로고
    • Clinical and prognostic significance of serum magnesium concentration in patients with severe chronic congestive heart failure: The PROMISE Study
    • Eichhorn EJ, Tandon PK, DiBianco R, Timmis GC, Fenster PE, Shannon J, Packer M: Clinical and prognostic significance of serum magnesium concentration in patients with severe chronic congestive heart failure: The PROMISE Study. J Am Coll Cardiol (1993) 21:634-640.
    • (1993) J Am Coll Cardiol , vol.21 , pp. 634-640
    • Eichhorn, E.J.1    Tandon, P.K.2    DiBianco, R.3    Timmis, G.C.4    Fenster, P.E.5    Shannon, J.6    Packer, M.7
  • 13
    • 0027991399 scopus 로고
    • The association of levels of serum potassium and magnesium with ventricular premature complexes (the Framingham Heart Study)
    • note
    • Tsuji H, Venditti FJ Jr, Evans JC, Larson MG, Levy D: The association of levels of serum potassium and magnesium with ventricular premature complexes (the Framingham Heart Study). Am J Cardiol (1994) 74:232-235. A Framingham Heart Study analysis of the arrhythmic potential of decreased levels of potassium and magnesium.
    • (1994) Am J Cardiol , vol.74 , pp. 232-235
    • Tsuji, H.1    Venditti F.J., Jr.2    Evans, J.C.3    Larson, M.G.4    Levy, D.5
  • 14
  • 15
    • 0029122569 scopus 로고
    • Two new culprits in cardiovascular disease: QT dispersion and aldosterone
    • Struthers AD: Two new culprits in cardiovascular disease: QT dispersion and aldosterone. J Hum Hypertens (1995) 9:659-661.
    • (1995) J Hum Hypertens , vol.9 , pp. 659-661
    • Struthers, A.D.1
  • 16
    • 0028860490 scopus 로고
    • Effects of adding spironolactone to an angiotensin-converting enzyme inhibitor in chronic congestive heart failure secondary to coronary artery disease
    • Barr CS, Lang CC, Hanson J, Arnott M, Kennedy N, Struthers AD: Effects of adding spironolactone to an angiotensin-converting enzyme inhibitor in chronic congestive heart failure secondary to coronary artery disease. Am J Cardiol (1995) 76:1259-1265.
    • (1995) Am J Cardiol , vol.76 , pp. 1259-1265
    • Barr, C.S.1    Lang, C.C.2    Hanson, J.3    Arnott, M.4    Kennedy, N.5    Struthers, A.D.6
  • 17
    • 0026638123 scopus 로고
    • Reactive and reparative myocardial fibrosis in arterial hypertension in the rat
    • note
    • Brilla CG, Weber KT: Reactive and reparative myocardial fibrosis in arterial hypertension in the rat. Cardiovasc Res (1992) 26:671-677. A study demonstrating the pathological effect of aldosterone excess on myocardial structure in an animal model.
    • (1992) Cardiovasc Res , vol.26 , pp. 671-677
    • Brilla, C.G.1    Weber, K.T.2
  • 19
    • 0028097678 scopus 로고
    • QT dispersion and sudden unexpected death in chronic heart failure
    • Barr CS, Naas A, Freeman N, Lang CC, Struthers AD: QT dispersion and sudden unexpected death in chronic heart failure. Lancet (1994) 343:327-329.
    • (1994) Lancet , vol.343 , pp. 327-329
    • Barr, C.S.1    Naas, A.2    Freeman, N.3    Lang, C.C.4    Struthers, A.D.5
  • 20
    • 0026718015 scopus 로고
    • Aldosterone reduces baroreceptor discharge in the dog
    • Wang W, McClain JM, Zucker IH: Aldosterone reduces baroreceptor discharge in the dog. Hypertension (1992) 19:270-277.
    • (1992) Hypertension , vol.19 , pp. 270-277
    • Wang, W.1    McClain, J.M.2    Zucker, I.H.3
  • 22
    • 0034688194 scopus 로고    scopus 로고
    • Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The heart outcomes prevention evaluation study investigators
    • note
    • Yusuf S, Sleight P, Pogue J, Bosch J, Davies R, Dagenais G: Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The heart outcomes prevention evaluation study investigators. N Engl J Med (2000) 342:145-153. The HOPE Trial, which confirmed the benefit of ACE inhibition in patients at high risk for cardiovascular events.
    • (2000) N Engl J Med , vol.342 , pp. 145-153
    • Yusuf, S.1    Sleight, P.2    Pogue, J.3    Bosch, J.4    Davies, R.5    Dagenais, G.6
  • 23
    • 0027415303 scopus 로고
    • Role of aldosterone in congestive heart failure
    • Weber KT, Villarreal D: Role of aldosterone in congestive heart failure. Postgrad Med (1993) 93:203-207, 211-212, 216-218 passim.
    • (1993) Postgrad Med , vol.93
    • Weber, K.T.1    Villarreal, D.2
  • 24
    • 0030587794 scopus 로고    scopus 로고
    • Effectiveness of spironolactone added to an angiotensin-converting enzyme inhibitor and a loop diuretic for severe chronic congestive heart failure (the Randomized Aldactone Evaluation Study [RALES])
    • Effectiveness of spironolactone added to an angiotensin-converting enzyme inhibitor and a loop diuretic for severe chronic congestive heart failure (the Randomized Aldactone Evaluation Study [RALES]). Am J Cardiol (1996) 78:902-907.
    • (1996) Am J Cardiol , vol.78 , pp. 902-907
  • 25
    • 0029550256 scopus 로고
    • Aldosterone escape during ACE inhibitor therapy in chronic heart failure
    • Struthers AD: Aldosterone escape during ACE inhibitor therapy in chronic heart failure. Eur Heart J (1995) 16:103-106.
    • (1995) Eur Heart J , vol.16 , pp. 103-106
    • Struthers, A.D.1
  • 26
    • 0027759245 scopus 로고
    • Effects of long-term oral magnesium chloride replacement in congestive heart failure secondary to coronary artery disease
    • Bashir Y, Sneddon JF, Staunton HA, Haywood GA, Simpson IA, McKenna WJ, Camm AJ: Effects of long-term oral magnesium chloride replacement in congestive heart failure secondary to coronary artery disease. Am J Cardiol (1993) 72:1156-1162.
    • (1993) Am J Cardiol , vol.72 , pp. 1156-1162
    • Bashir, Y.1    Sneddon, J.F.2    Staunton, H.A.3    Haywood, G.A.4    Simpson, I.A.5    McKenna, W.J.6    Camm, A.J.7
  • 27
    • 0013459681 scopus 로고
    • And pressor agents in vascular smooth muscle
    • And pressor agents in vascular smooth muscle. Hypertension (1983) 5:141-146.
    • (1983) Hypertension , vol.5 , pp. 141-146
  • 28
    • 0034651798 scopus 로고    scopus 로고
    • Spironlactone increases nitric oxide bioactivity, improves endothelial vasodilator dysfunction, and suppresses vascular angiotensin I/angiotensin II conversion in patients with chronic heart failure
    • Farquharson CAJ, Struthers AD: Spironlactone increases nitric oxide bioactivity, improves endothelial vasodilator dysfunction, and suppresses vascular angiotensin I/angiotensin II conversion in patients with chronic heart failure. Circulation (2000) 101:594-597.
    • (2000) Circulation , vol.101 , pp. 594-597
    • Farquharson, C.A.J.1    Struthers, A.D.2
  • 29
    • 0025675680 scopus 로고
    • Remodeling of the rat right and left ventricle in experimental hypertension
    • Brilla CG, Pick R, Tan LB, Janicki JS, Weber KT: Remodeling of the rat right and left ventricle in experimental hypertension. Circ Res (1990) 67:1355-1364.
    • (1990) Circ Res , vol.67 , pp. 1355-1364
    • Brilla, C.G.1    Pick, R.2    Tan, L.B.3    Janicki, J.S.4    Weber, K.T.5
  • 30
    • 0027227646 scopus 로고
    • Anti-aldosterone treatment and the prevention of myocardial fibrosis in primary and secondary hyperaldosteronism
    • Brilla CG, Matsubara LS, Weber KT: Anti-aldosterone treatment and the prevention of myocardial fibrosis in primary and secondary hyperaldosteronism. J Mol Cell Cardiol (1993) 25:563-575.
    • (1993) J Mol Cell Cardiol , vol.25 , pp. 563-575
    • Brilla, C.G.1    Matsubara, L.S.2    Weber, K.T.3
  • 31
    • 0030809598 scopus 로고    scopus 로고
    • Fibrosis of atria and great vessels in response to angiotensin II or aldosterone infusion
    • Sun Y, Ramires FJA, Weber KT: Fibrosis of atria and great vessels in response to angiotensin II or aldosterone infusion. Cardiovasc Res (1997) 35:138-147.
    • (1997) Cardiovasc Res , vol.35 , pp. 138-147
    • Sun, Y.1    Ramires, F.J.A.2    Weber, K.T.3
  • 32
    • 0027379861 scopus 로고
    • Pathologic remodelling of the myocardium in a weightlifter taking anabolic steroids
    • Campbell SE, Farb A, Weber KT: Pathologic remodelling of the myocardium in a weightlifter taking anabolic steroids. Blood Press (1993) 2:213-216.
    • (1993) Blood Press , vol.2 , pp. 213-216
    • Campbell, S.E.1    Farb, A.2    Weber, K.T.3
  • 33
    • 0003100633 scopus 로고    scopus 로고
    • Effects of the selective mineralocorticoid receptor antagonist, eplerenone, in a model of aldosterone-induced hypertension and cardiac fibrosis
    • Frierdich G, Schuh J, Brown M, Nochowiak D, Blehm D, Delyani JA: Effects of the selective mineralocorticoid receptor antagonist, eplerenone, in a model of aldosterone-induced hypertension and cardiac fibrosis. Am J Hypertens (1998) 11:94A.
    • (1998) Am J Hypertens , vol.11
    • Frierdich, G.1    Schuh, J.2    Brown, M.3    Nochowiak, D.4    Blehm, D.5    Delyani, J.A.6
  • 34
    • 0034126414 scopus 로고    scopus 로고
    • Mineralocorticoid receptor antagonists: The evolution of utility and pharmacology
    • note
    • Delyani JA: Mineralocorticoid receptor antagonists: The evolution of utility and pharmacology. Kidney Int (2000) 57:1408-1411. A pharmacological review of the actions of aldosterone receptor antagonists.
    • (2000) Kidney Int , vol.57 , pp. 1408-1411
    • Delyani, J.A.1
  • 36
    • 0028786493 scopus 로고
    • The aminoterminal propeptide of type III procollagen provides new information on prognosis after acute myocardial infarction
    • Høst NB, Jensen LT, Bendixen PM, Jensen SE, Koldkjær OG, Simonsen EE: The aminoterminal propeptide of type III procollagen provides new information on prognosis after acute myocardial infarction. Am J Cardiol (1995) 76:869-873.
    • (1995) Am J Cardiol , vol.76 , pp. 869-873
    • Høst, N.B.1    Jensen, L.T.2    Bendixen, P.M.3    Jensen, S.E.4    Koldkjær, O.G.5    Simonsen, E.E.6
  • 37
    • 0034727695 scopus 로고    scopus 로고
    • Limitatioon of excessive extracellular matrix turnover may contribute to survival benefit of spironolactone therapy in patients with congestive heart failure: Insights from the randomized aldactone evaluation study (RALES). RALES Investigators
    • note
    • Zannad F, Alla F, Dousset B, Perez A, Pitt B: Limitatioon of excessive extracellular matrix turnover may contribute to survival benefit of spironolactone therapy in patients with congestive heart failure: Insights from the randomized aldactone evaluation study (RALES). RALES Investigators. Circulation (2000) 102:2700-2706. An analysis of the RALES Trial population investigating the effects of spironolactone on markers of myocardial fibrosis.
    • (2000) Circulation , vol.102 , pp. 2700-2706
    • Zannad, F.1    Alla, F.2    Dousset, B.3    Perez, A.4    Pitt, B.5
  • 38
    • 0029550133 scopus 로고
    • ACE inhibitor co-therapy in patients with heart failure: Rationale for the Randomized Aldactone Evaluation Study (RALES)
    • Pitt B: ACE inhibitor co-therapy in patients with heart failure: Rationale for the Randomized Aldactone Evaluation Study (RALES). Eur Heart J (1995) 16:107-110.
    • (1995) Eur Heart J , vol.16 , pp. 107-110
    • Pitt, B.1
  • 39
    • 0023266532 scopus 로고
    • Effects of enalapril on mortality in severe congestive heart failure. Results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS). The CONSENSUS Trial Study Group
    • note
    • Effects of enalapril on mortality in severe congestive heart failure. Results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS). The CONSENSUS Trial Study Group. N Engl J Med (1987) 316:1429-1435. The CONSENSUS trial; one of the earlier trials to document the reduction in morbidity and mortality associated with ACE inhibitor therapy for congestive heart failure.
    • (1987) N Engl J Med , vol.316 , pp. 1429-1435


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.