FLT3 internal tandem duplication mutations are rare in agnogenic myeloid metaplasia [2]

Blood

Volumn 100, Issue 1, 2002, Pages 364-

  Abu Duhier, Faisal M ^a   Goodeve, Anne C ^a   Wilson, Gill A ^a   Carr, Rory S ^a   Peake, Ian R ^a   Reilly, John T ^a  

^a ROYAL HALLAMSHIRE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

FLT3 LIGAND; CD135 ANTIGEN; FLT3 PROTEIN, HUMAN; ONCOPROTEIN; PROTEIN TYROSINE KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; BONE MARROW TRANSPLANTATION; CONTROLLED STUDY; DISEASE COURSE; DNA SCREENING; FIBROSIS; GENE MUTATION; LETTER; LEUKOCYTOSIS; MOUSE; MYELOID METAPLASIA; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SPLENOMEGALY; CASE CONTROL STUDY; GENE FREQUENCY; GENETICS; HUMAN; MUTATION; NOTE; NUCLEOTIDE SEQUENCE; PATHOLOGY; TANDEM REPEAT;

CASE-CONTROL STUDIES; DNA MUTATIONAL ANALYSIS; FMS-LIKE TYROSINE KINASE 3; GENE FREQUENCY; HUMANS; MUTATION; MYELOID METAPLASIA; PROTO-ONCOGENE PROTEINS; RECEPTOR PROTEIN-TYROSINE KINASES; TANDEM REPEAT SEQUENCES;

EID: 0036659956     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2002-02-0536     Document Type: Letter

References (5)

1. Kelly LM, Liu Q, Kutok JL, et al. FLT3 internal tandem duplication mutations associated with human acute myeloid leukemias induce myeloproliferative disease in a murine bone marrow transplant model. Blood. 2002;99:310-318.
2. Abu-Duhier FM, Goodeve AC, Wilson GA, et al. FLT3 internal tandem duplication mutations in adult myeloid leukaemia define a high risk group. Br J Haematol. 2000;111:190-195.
3. Abu-Duhier FM, Goodeve AC, Wilson GA, et al. Genomic structure of human FLT3: implications for mutational analysis. Br J Haematol. 2001;113:1076-1077.
4. Horiike S, Yokota S, Nakao M, et al. Tandem duplications of the FLT3 receptor gene are associated with leukemic transformation of myelodysplasia. Leukemia. 1997;11:1442-1446.
5. Nakano Y, Kiyoi H, Miyawaki S, et al. Molecular evolution of acute myeloid leukemia in relapse: unstable N-ras and FLT3 genes compared with p53 gene. Br J Haematol. 1999;104:659-664.