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1
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0033851515
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Myocardial infarction redefined-a consensus statement of the joint ecs/acc committee for the redefinition of myocardial infarction
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The Joint European Society of Cardiology/American College of Cardiology Committee: This reference provides the revised criteria for definition of MI reflecting broad international consensus. The redefinition emphasizes the diagnostic sensitivity and prognostic importance of troponin testing and also provides standards for defining the reference limit and assay precision at the reference limit
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The Joint European Society of Cardiology/American College of Cardiology Committee: Myocardial infarction redefined-a consensus statement of the joint ECS/ACC committee for the redefinition of myocardial infarction. J Am Coll Cardiol 2000, 36:959-969. This reference provides the revised criteria for definition of MI reflecting broad international consensus. The redefinition emphasizes the diagnostic sensitivity and prognostic importance of troponin testing and also provides standards for defining the reference limit and assay precision at the reference limit.
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(2000)
J Am Coll Cardiol
, vol.36
, pp. 959-969
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2
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0030664975
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Emergency room triage of patients with acute chest pain by means of rapid testing for cardiac troponin t or troponin i
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Hamm C, Goldmann BU, Heeschen C, et al.: Emergency room triage of patients with acute chest pain by means of rapid testing for cardiac troponin T or troponin I. N Engl J Med 1997, 337:1648-1653.
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(1997)
N Engl J Med
, vol.337
, pp. 1648-1653
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Hamm, C.1
Goldmann, B.U.2
Heeschen, C.3
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3
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0006894580
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For the gusto iia investigators: Cardiac troponin t levels for risk stratification in acute myocardial ischemia
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Ohman EM, Armstrong PW, Christenson RH, et al., for the GUSTO IIa Investigators: Cardiac troponin T levels for risk stratification in acute myocardial ischemia. N Engl J Med 1996, 335:1333-1341.
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(1996)
N Engl J Med
, vol.335
, pp. 1333-1341
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Ohman, E.M.1
Armstrong, P.W.2
Christenson, R.H.3
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4
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6744240314
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Cardiac-specific troponin i levels to predict the risk of mortality in patients with acute coronary syndromes
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Antman EM, Tanasijevic MJ, Thompson B, et al.: Cardiac-specific troponin I levels to predict the risk of mortality in patients with acute coronary syndromes. N Engl J Med 1996, 335:1342-1349.
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(1996)
N Engl J Med
, vol.335
, pp. 1342-1349
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Antman, E.M.1
Tanasijevic, M.J.2
Thompson, B.3
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5
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0033669294
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Elevated cardiac troponin levels predict the risk of adverse outcome in patients with acute coronary syndromes
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A thorough and well-done systematic overview and meta-analysis of the results of studies of troponin testing across the spectrum of ACS presentations. Clearly presents the prognostic importance of baseline troponin elevations in both ST-segment elevation and non-ST-segment elevation ACS
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Ottani F, Galvani M, Nicolini FA, et al.: Elevated cardiac troponin levels predict the risk of adverse outcome in patients with acute coronary syndromes. Am Heart J 2000, 140:917-927. A thorough and well-done systematic overview and meta-analysis of the results of studies of troponin testing across the spectrum of ACS presentations. Clearly presents the prognostic importance of baseline troponin elevations in both ST-segment elevation and non-ST-segment elevation ACS.
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(2000)
Am Heart J
, vol.140
, pp. 917-927
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Ottani, F.1
Galvani, M.2
Nicolini, F.A.3
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6
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0034884193
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The prognostic value of troponin in patients with non-st elevation acute coronary syndromes: A meta-analysis
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Heidenreich PA, Alloggiamento T, Melsop K, et al.: The prognostic value of troponin in patients with non-ST elevation acute coronary syndromes: a meta-analysis. J Am Coll Cardiol 2001, 38:478-485.
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(2001)
J Am Coll Cardiol
, vol.38
, pp. 478-485
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Heidenreich, P.A.1
Alloggiamento, T.2
Melsop, K.3
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7
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0031032540
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Troponin t identifies patients with unstable coronary artery disease who benefit from longterm antithrombotic protection
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Lindahl B, Venge P, Wallentin L: Troponin T identifies patients with unstable coronary artery disease who benefit from longterm antithrombotic protection. J Am Coll Cardiol 1997, 29:43-48.
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(1997)
J Am Coll Cardiol
, vol.29
, pp. 43-48
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Lindahl, B.1
Venge, P.2
Wallentin, L.3
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8
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0033609314
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Benefit of abciximab in patients with refractory unstable angina in relation to serum troponin t levels
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Hamm CW, Heeschen C, Goldmann B, et al.: Benefit of abciximab in patients with refractory unstable angina in relation to serum troponin T levels. N Engl J Med 1999, 340:1623-1629.
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(1999)
N Engl J Med
, vol.340
, pp. 1623-1629
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Hamm, C.W.1
Heeschen, C.2
Goldmann, B.3
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9
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0033527377
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Angiographic findings in patients with refractory unstable angina according to troponin t status
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Heeschen C, van den Brand MJ, Hamm CW, Simoons ML: Angiographic findings in patients with refractory unstable angina according to troponin T status. Circulation 1999, 100:1509-1514.
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(1999)
Circulation
, vol.100
, pp. 1509-1514
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Heeschen, C.1
Van Den Brand, M.J.2
Hamm, C.W.3
Simoons, M.L.4
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10
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0033589739
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Troponin concentrations for stratification of patients with acute coronary syndromes in relation to therapeutic efficacy of tirofiban
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Heeschen C, Hamm CW, Goldmann B, Deu A, et al.: Troponin concentrations for stratification of patients with acute coronary syndromes in relation to therapeutic efficacy of tirofiban. Lancet 1999, 354:1757-1762.
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(1999)
Lancet
, vol.354
, pp. 1757-1762
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Heeschen, C.1
Hamm, C.W.2
Goldmann, B.3
Deu, A.4
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11
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0035912912
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Benefit of glycoprotein iib/iiia inhibition in patients with acute coronary syndromes and troponin t-positive status: The paragon-b troponin t substudy
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Newby LK, Ohman EM, Christenson RH, et al.: Benefit of glycoprotein IIb/IIIa inhibition in patients with acute coronary syndromes and troponin T-positive status: the PARAGON-B troponin T substudy. Circulation 2001, 103:2891-2896.
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(2001)
Circulation
, vol.103
, pp. 2891-2896
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Newby, L.K.1
Ohman, E.M.2
Christenson, R.H.3
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12
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0037132843
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Platelet glycoprotein iib/iiia inhibitors in acute coronary syndromes: A meta-analysis of all major randomised clinical trials
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Meta-analysis of all trials of GP IIb/IIIa inhibitors in ACS clearly demonstrating the troponin status by treatment interaction in which patients who are troponin-positive at baseline derive enhanced benefit from treatment with GP IIb/IIIa inhibitors relative to patients who are troponin-negative at baseline
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Boersma E, Harrington RA, Moliterno DJ, et al.: Platelet glycoprotein IIb/IIIa inhibitors in acute coronary syndromes: a meta-analysis of all major randomised clinical trials. Lancet 2002, 359:189-198. Meta-analysis of all trials of GP IIb/IIIa inhibitors in ACS clearly demonstrating the troponin status by treatment interaction in which patients who are troponin-positive at baseline derive enhanced benefit from treatment with GP IIb/IIIa inhibitors relative to patients who are troponin-negative at baseline.
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(2002)
Lancet
, vol.359
, pp. 189-198
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Boersma, E.1
Harrington, R.A.2
Moliterno, D.J.3
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13
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0035930101
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Ability of minor elevations of troponins i and t to predict benefit from an early invasive strategy in patients with unstable angina and non-st elevation myocardial infarction: Results from a randomized trial
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Morrow DA, Cannon CP, Rifai N, et al.: Ability of minor elevations of troponins I and T to predict benefit from an early invasive strategy in patients with unstable angina and non-ST elevation myocardial infarction: results from a randomized trial. JAMA 2001, 286:2405-2412.
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(2001)
JAMA
, vol.286
, pp. 2405-2412
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Morrow, D.A.1
Cannon, C.P.2
Rifai, N.3
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14
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0034222936
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Outcome at 1 year after an invasive compared with a non-invasive strategy in unstable coronary-artery disease: The frisc ii invasive randomised trial
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Wallentin L, Lagerqvist B, Husted S, et al.: Outcome at 1 year after an invasive compared with a non-invasive strategy in unstable coronary-artery disease: the FRISC II invasive randomised trial. Lancet 2000, 356:9-16.
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(2000)
Lancet
, vol.356
, pp. 9-16
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Wallentin, L.1
Lagerqvist, B.2
Husted, S.3
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15
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0034806576
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Mechanisms behind the prognostic value of troponin t in unstable coronary artery disease: A frisc ii substudy
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Lindahl B, Diderholm E, Lagerqvist B, et al.: Mechanisms behind the prognostic value of troponin T in unstable coronary artery disease: a FRISC II substudy. J Am Coll Cardiol 2001, 38:979-986.
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(2001)
J Am Coll Cardiol
, vol.38
, pp. 979-986
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Lindahl, B.1
Diderholm, E.2
Lagerqvist, B.3
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16
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0034961506
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Myoglobin levels at 12 hours identify patients at low risk for 30-day mortality after thrombolysis in acute myocardial infarction: A timi 10b substudy
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Srinivas VS, Cannon CP, Gibson CM, et al.: Myoglobin levels at 12 hours identify patients at low risk for 30-day mortality after thrombolysis in acute myocardial infarction: a TIMI 10B substudy. Am Heart J 2001, 142:29-36.
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(2001)
Am Heart J
, vol.142
, pp. 29-36
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Srinivas, V.S.1
Cannon, C.P.2
Gibson, C.M.3
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17
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0035836612
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Bedside multimarker testing for risk stratification in chest pain units: The checkmate study
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This is the first prospective study to demonstrate the importance of a multimarker strategy of biomarker testing including myoglobin, and performed at the point of care to identify and risk stratify high-risk patients from among those with low-risk presentations with chest pain and nondiagnostic ECGs
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Newby LK, Storrow AB, Gibler WB, et al.: Bedside multimarker testing for risk stratification in chest pain units: the CHECKMATE study. Circulation 2001, 103:1832-1837. This is the first prospective study to demonstrate the importance of a multimarker strategy of biomarker testing including myoglobin, and performed at the point of care to identify and risk stratify high-risk patients from among those with low-risk presentations with chest pain and nondiagnostic ECGs.
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(2001)
Circulation
, vol.103
, pp. 1832-1837
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Newby, L.K.1
Storrow, A.B.2
Gibler, W.B.3
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18
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0034111390
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For the capture investigators: Predictive value of c-reactive protein and troponin t in patients with unstable angina: A comparative analysis
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Heeschen C, Hamm CW, Bruemmer J, Simoons ML, for the CAPTURE investigators: Predictive value of C-reactive protein and troponin T in patients with unstable angina: a comparative analysis. J Am Coll Cardiol 2000, 35:1535-1542.
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(2000)
J Am Coll Cardiol
, vol.35
, pp. 1535-1542
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Heeschen, C.1
Hamm, C.W.2
Bruemmer, J.3
Simoons, M.L.4
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19
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0031746866
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C-reactive protein is a potent predictor of mortality independently of and in combination with troponin t in acute coronary syndromes: A timi 11a substudy
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Morrow DA, Rifai N, Antman EM, et al.: C-reactive protein is a potent predictor of mortality independently of and in combination with troponin T in acute coronary syndromes: a TIMI 11A substudy. J Am Coll Cardiol 1998, 31:1460-1465.
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(1998)
J Am Coll Cardiol
, vol.31
, pp. 1460-1465
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Morrow, D.A.1
Rifai, N.2
Antman, E.M.3
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20
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0034687438
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Markers of myocardial damage and inflammation in relation to long-term mortality in unstable coronary artery disease
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Lindahl B, Toss H, Siegbahn A, et al.: Markers of myocardial damage and inflammation in relation to long-term mortality in unstable coronary artery disease. N Engl J Med 2000, 343:1139-1147.
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(2000)
N Engl J Med
, vol.343
, pp. 1139-1147
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Lindahl, B.1
Toss, H.2
Siegbahn, A.3
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21
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0035824178
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Relationship between interleukin-6 and mortality in patients with unstable coronary artery disease
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This study demonstrates that a marker of inflammation, interleukin-6, may be useful in discriminating acute coronary syndrome patients who could benefit preferentially from an early invasive strategy of management
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Lindmark E, Diderholm E, Wallentin L, Siegbahn A: Relationship between interleukin-6 and mortality in patients with unstable coronary artery disease. JAMA 2001, 286:2107-2113. This study demonstrates that a marker of inflammation, interleukin-6, may be useful in discriminating acute coronary syndrome patients who could benefit preferentially from an early invasive strategy of management.
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(2001)
JAMA
, vol.286
, pp. 2107-2113
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Lindmark, E.1
Diderholm, E.2
Wallentin, L.3
Siegbahn, A.4
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22
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0035807597
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The prognostic value of b-type natriuretic peptide in patients with acute coronary syndromes
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This study demonstrates the possibility of using non-necrosis markers, in this case BNP, to augment clinical, ECG and troponins tools in risk stratification of patients across the spectrum of ACS
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De Lemos JA, Marrow DA, Bentley JH, et al.: The prognostic value of B-type natriuretic peptide in patients with acute coronary syndromes. N Engl J Med 2001, 345:1014-1021. This study demonstrates the possibility of using non-necrosis markers, in this case BNP, to augment clinical, ECG and troponins tools in risk stratification of patients across the spectrum of ACS.
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(2001)
N Engl J Med
, vol.345
, pp. 1014-1021
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De Lemos, J.A.1
Marrow, D.A.2
Bentley, J.H.3
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23
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0035807592
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Pregnancyassociated plasma protein a as a marker of acute coronary syndromes
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Bayes-Genis A, Conover CA, Overgaard MT, et al.: Pregnancyassociated plasma protein A as a marker of acute coronary syndromes. N Engl J Med 2001, 345:1022-1029.
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(2001)
N Engl J Med
, vol.345
, pp. 1022-1029
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Bayes-Genis, A.1
Conover, C.A.2
Overgaard, M.T.3
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24
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0033765993
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A novel assay for cobalt-albumin binding and its potential as a marker for myocardial ischemia: A preliminary report
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Bar-Or D, Lau E, Winkler JV: A novel assay for cobalt-albumin binding and its potential as a marker for myocardial ischemia: a preliminary report. J Emerg Med 2000, 19:311-315.
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(2000)
J Emerg Med
, vol.19
, pp. 311-315
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Bar-Or, D.1
Lau, E.2
Winkler, J.V.3
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25
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0038634588
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Reduced albumin-cobalt binding with transient myocardial ischemia after elective percutaneous transluminal coronary angioplasty: A preliminary comparison to creatine kinase-mb, myoglobin, and troponin i
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Bar-Or D, Winkler JV, Vanbenthuysen K, et al.: Reduced albumin-cobalt binding with transient myocardial ischemia after elective percutaneous transluminal coronary angioplasty: a preliminary comparison to creatine kinase-MB, myoglobin, and troponin I. Am Heart J 2001, 141:985-991.
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(2001)
Am Heart J
, vol.141
, pp. 985-991
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Bar-Or, D.1
Winkler, J.V.2
Vanbenthuysen, K.3
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26
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0034042774
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Human heart-type cytoplasmic fatty acid-binding protein (h-fabp) for the diagnosis of acute myocardial infarction. Clinical evaluation of h-fabp in comparison with myoglobin and creatine kinase isoenzyme mb
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Okamoto F, Sohmiya K, Ohkaru Y, et al.: Human heart-type cytoplasmic fatty acid-binding protein (H-FABP) for the diagnosis of acute myocardial infarction. Clinical evaluation of H-FABP in comparison with myoglobin and creatine kinase isoenzyme MB. Clin Chem Lab Med 2000, 38:231-238.
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(2000)
Clin Chem Lab Med
, vol.38
, pp. 231-238
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Okamoto, F.1
Sohmiya, K.2
Ohkaru, Y.3
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27
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0034762556
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Assessment of coronary reperfusion in patients with myocardial infarction using fatty acid binding protein concentrations in plasma
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De Groot MJ, Muijtjens AM, Simoons ML, et al.: Assessment of coronary reperfusion in patients with myocardial infarction using fatty acid binding protein concentrations in plasma. Heart 2001, 85:278-285.
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(2001)
Heart
, vol.85
, pp. 278-285
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De Groot, M.J.1
Muijtjens, A.M.2
Simoons, M.L.3
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28
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0034968361
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Development of a simple whole blood panel test for detection of human heart-type fatty acid-binding protein
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Watanbe T, Ohkubo Y, Matsuoka H: Development of a simple whole blood panel test for detection of human heart-type fatty acid-binding protein. Clin Biochem 2001, 34:257-263.
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(2001)
Clin Biochem
, vol.34
, pp. 257-263
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Watanbe, T.1
Ohkubo, Y.2
Matsuoka, H.3
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