Leptin affects adenylate cyclase activity in H9c2 cardiac cell line: Effects of short- and long-term exposure

American Journal of Hypertension

Volumn 15, Issue 7 I, 2002, Pages 638-643

  Illiano, Gennaro ^a   Naviglio, Silvio ^a   Pagano, Mario ^a   Spina, Annamaria ^a   Chiosi, Emilio ^a   Barbieri, Michelangela ^a   Paolisso, Giuseppe ^a  

^a SECOND UNIVERSITY OF NAPLES   (Italy)

Author keywords

Adenylate cyclase; Cardiac cells; Catecholamine; G protein; Leptin

Indexed keywords

ADENYLATE CYCLASE; CATECHOLAMINE; GUANINE NUCLEOTIDE BINDING PROTEIN; ISOPRENALINE; LEPTIN; NORADRENALIN; PROTEIN DERIVATIVE; PROTEIN P21; RAS PROTEIN; ALPHA ADRENERGIC RECEPTOR STIMULATING AGENT; CARDIOTONIC AGENT;

ANIMAL CELL; ARTICLE; CELL LINE; COMPLEX FORMATION; CONGESTIVE HEART FAILURE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ANALYSIS; HEART MUSCLE CELL; HYPERTENSION; LONG TERM EXPOSURE; MOLECULAR INTERACTION; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN CONTENT; RAT; ANIMAL; CYTOLOGY; DRUG EFFECT; DRUG INTERACTION; ENZYMOLOGY; METABOLISM;

ADENYLATE CYCLASE; ADRENERGIC ALPHA-AGONISTS; ANIMAL; CARDIOTONIC AGENTS; CELL LINE; DRUG INTERACTIONS; ENZYME ACTIVATION; GTP-BINDING PROTEINS; ISOPROTERENOL; LEPTIN; MYOCYTES, CARDIAC; NOREPINEPHRINE; RATS; ANIMALS;

EID: 0036632254     PISSN: 08957061     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0895-7061(02)02925-4     Document Type: Article

References (25)

1. Obesity as an independent risk factor for cardiovascular disease: A 26-year follow-up of participants in the Framingham Heart Study
2. Diabetes, hypertension and cardiovascular disease: An update
3. Obesity and cardiovascular disease: The Framingham Study
4. Obesity, hypertension and the heart
5. Plasma leptin level is associated with myocardial wall thickness in hypertensive insulin-resistant men
6. Chronic leptin infusion increases arterial pressure
7. Plasma leptin concentrations and cardiac autonomic nervous system in healthy subjects with different body weights
8. Leptin-induced lipolysis opposes the tonic inhibition of endogenous adenosine in white adipocytes
9. Leptin inhibits insulin secretion induced by cellular cAMP in a pancreatic B cell line (INS-1 cells)
10. The molecular basis for distinct β-adrenergic receptor subtype actions in cardiomyocytes
11. Regulation of β-adrenoceptor signaling in cardiac function and disease
12. A highly sensitive adenylate cyclase assay
13. Receptor mediated regional sympathetic nerve activation by leptin
14. Relationship between muscle sympathetic nerve activity and plasma leptin concentration
15. Congestive heart failure: Fifty years of progress
16. Expression of β-arrestins and β-adrenergic receptor kinases in the failing human heart
17. β-Adrenergic receptor blockade in chronic heart failure
18. Adverse effects of chronic endogenous sympathetic drive induced by cardiac Gsα overexpression
19. Cardiomyopathy induced by cardiac Gs alpha overexpression
20. Determinants of the cardiomyopathic phenotyoe in chimeric mice overexpressing cardiac Gsα
21. Leptin
22. Divergent signaling capacities of the long and short isoforms of the leptin receptor
23. Increasing complexity of Ras signaling
24. Leptin can induce proliferation, differentiation and functional activation of haemopoietic cells
25. The leptin receptor activates janus kinase 2 and signals for proliferation in a factor dependent cell line