Development of simplified and rapid detection assay for genetic polymorphisms influencing drug response and its clinical applications

Yakugaku Zasshi

Volumn 122, Issue 7, 2002, Pages 451-463

  Hiratsuka, Masahiro ^a  

^a TOHOKU UNIVERSITY HOSPITAL   (Japan)

Author keywords

Pharmacogenetics; Real time PCR; Single nucleotide polymorphism

Indexed keywords

ARYLAMINE ACETYLTRANSFERASE; CHOLESTEROL ESTER TRANSFER PROTEIN; CYTOCHROME P450 2A6; CYTOCHROME P450 2B6; CYTOCHROME P450 2C18; CYTOCHROME P450 2C19; CYTOCHROME P450 2C9; CYTOCHROME P450 2D6; CYTOCHROME P450 2E1; CYTOCHROME P450 3A5; DRUG METABOLIZING ENZYME; GLUCURONOSYLTRANSFERASE 1A1; ISONIAZID; MITOCHONDRIAL DNA; MULTIDRUG RESISTANCE PROTEIN 1; SERINE PROTEINASE OMI; STROMAL CELL DERIVED FACTOR 1; UNCLASSIFIED DRUG; AMINOGLYCOSIDE; ANTIINFECTIVE AGENT; CYTOCHROME P450; MERCAPTOPURINE; METHYLTRANSFERASE; NAT2 PROTEIN, HUMAN; THIOPURINE METHYLTRANSFERASE; TOLBUTAMIDE;

DNA POLYMORPHISM; DRUG DETERMINATION; DRUG ERUPTION; DRUG METABOLISM; DRUG RESPONSE; DRUG TARGETING; ETHNIC GROUP; FEVER; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; INCIDENCE; NAUSEA; NEURITIS; PATIENT; POPULATION; PROTEIN DETERMINATION; REAL TIME POLYMERASE CHAIN REACTION; REVIEW; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICAL SIGNIFICANCE; VISUAL IMPAIRMENT; VOMITING; ADULT; BIOTRANSFORMATION; CASE REPORT; GENETICS; MALE; METHODOLOGY; PHARMACOGENETICS; POLYMERASE CHAIN REACTION;

6-MERCAPTOPURINE; ADULT; AMINOGLYCOSIDES; ANTI-BACTERIAL AGENTS; ARYLAMINE N-ACETYLTRANSFERASE; BIOTRANSFORMATION; CYTOCHROME P-450 ENZYME SYSTEM; DNA, MITOCHONDRIAL; GENOTYPE; HUMANS; ISONIAZID; MALE; METHYLTRANSFERASES; PHARMACOGENETICS; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; TOLBUTAMIDE;

EID: 0036631880     PISSN: 00316903     EISSN: None     Source Type: Journal    
DOI: 10.1248/yakushi.122.451     Document Type: Review

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