Detection of toxin production in Clostridium difficile strains by three different methods

Clinical Microbiology and Infection

Volumn 8, Issue 7, 2002, Pages 413-418

  Yucesoy M ^a   McCoubrey, J ^b   Brown, R ^b   Poxton, I R ^b  

^a DOKUZ EYLUL UNIVERSITY   (Turkey)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Antibiotic associated diarrhoea; Clostridium difficile; Cytopathic effect; Immunoassay; Tissue culture; Toxin A; Toxin B

Indexed keywords

CLOSTRIDIUM DIFFICILE TOXIN A; CLOSTRIDIUM DIFFICILE TOXIN B; VITRONECTIN;

ARTICLE; BACTERIAL STRAIN; BACTERIUM ISOLATE; CLOSTRIDIUM DIFFICILE; CONTROLLED STUDY; DIARRHEA; FECES ANALYSIS; IMMUNOASSAY; IN VITRO STUDY; INTERMETHOD COMPARISON; METHODOLOGY; NONHUMAN; PREDICTION AND FORECASTING; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; SEROTYPE; TISSUE CULTURE; VERO CELL;

BACTERIA (MICROORGANISMS); CLOSTRIDIUM; CLOSTRIDIUM DIFFICILE;

EID: 0036630189     PISSN: 1198743X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1469-0691.2002.00440.x     Document Type: Article

References (27)

1. Microbiology, epidemiology and diagnosis of Clostridium difficile infection
2. The cell wall proteins of Clostridium difficile
3. Variation in the surface layer proteins of Clostridium difficile
4. The pathogenicity of Clostridium difficile
5. Clostridium difficile-associated diarrhoea and length of hospital stay
6. Clostridium difficile-associated diarrhoea: Epidemiological data from Western Australia
7. Multicenter evaluation of a new enzyme immunoassay for detection of Clostridium difficile enterotoxin A
8. Enteropathogenic clostridia and Clostridium botulinum
9. Comparison of the ToxA test with cytotoxicity assay and culture for the detection of Clostridium difficile-associated diarrhoeal disease
10. Clinical considerations in the diagnosis of antimicrobial agent-associated gastroenteritis
11. Clostridium difficile: Clinical considerations
12. Comparison of four laboratory tests for diagnosis of Clostridium difficile-associated diarrhoea
13. Comparison of four commercially available rapid enzyme immunoassays with cytotoxin assay for detection of Clostridium difficile toxin (s) from stool specimens
14. Enzyme immunoassay for the detection of Clostridium difficile antigen
15. Multicentre evaluation of a commercial test for the rapid diagnosis of Clostridium difficile-mediated antibiotic-associated diarrhoea
16. Evaluation of six commercial assays for the rapid detection of Clostridium difficile toxin and/or antigen in stool specimens
17. Multicenter evaluation of the Clostridium difficile TOX A/B Test
18. Comparison of the TOX A/B test to a cell culture cytotoxicity assay for the detection of Clostridium difficile in stools
19. Comparison of three enzyme immunoassays, a cytotoxicity assay, and toxigenic culture for diagnosis of Clostridium difficile-associated diarrhea
20. Evaluation of three commercial enzyme immunoassay kits for detecting faecal Clostridium difficile toxins
21. High prevalence of toxin A negative/toxin B positive Clostridium difficile strains among adult inpatients
22. Severe truncation of the toxin A gene in a pathogenic Clostridium difficile (CD) strain not detectable by toxin A immunoassay
23. Characterization of a toxin A-negative, toxin B-positive strain of Clostridium difficile responsible for a nosocomial outbreak of Clostridium difficile-associated diarrhea
24. Prevalence of toxin A negative /B positive Clostridium difficile strains
25. Serogroup F strains of Clostridium difficile produce toxin B but not toxin A
26. Acquisition of Clostridium difficile by hospitalized patients: Evidence for colonized new admissions as a source of infection