A Negative Regulatory Element Required for Light-Dependent pinopsin Gene Expression

Journal of Neuroscience

Volumn 22, Issue 11, 2002, Pages 4357-4363

  Takanaka, Yoko ^a   Okano, Toshiyuki ^a   Yamamoto, Kazuyuki ^a   Fukada, Yoshitaka ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Chicken; Gene expression; Light induction; Pineal gland; pinopsin gene; Transcriptional regulation

Indexed keywords

DNA FRAGMENT; LUCIFERASE; NUCLEAR FACTOR; PINOPSIN; PROTEIN; UNCLASSIFIED DRUG; AVIAN PROTEIN; CRYSTALLIN; HOMEODOMAIN PROTEIN; NERVE PROTEIN; NUCLEAR PROTEIN; OLIGONUCLEOTIDE; OPSIN; PINOPSIN PROTEIN, CHICKEN; REPRESSOR PROTEIN; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING SITE; CELL CULTURE; CHICKEN; CONTROLLED STUDY; DARKNESS; E BOX ELEMENT; EMBRYO; FIBROBLAST; GEL MOBILITY SHIFT ASSAY; GENE CONSTRUCT; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE FUSION; GENE MUTATION; GENE REPRESSION; GENETIC TRANSFECTION; LIGHT; MOUSE; NONHUMAN; PINEAL BODY; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN BINDING; REGULATORY MECHANISM; REPORTER GENE; SIMIAN VIRUS 40; VIRUS GENE; ANIMAL; BINDING COMPETITION; CELL STRAIN 3T3; CHEMISTRY; CYTOLOGY; DNA FLANKING REGION; DRUG EFFECT; GENE SILENCING; GENETICS; METABOLISM; PHYSIOLOGY; RADIATION EXPOSURE; REGULATORY SEQUENCE; SITE DIRECTED MUTAGENESIS;

3T3 CELLS; 5' FLANKING REGION; ANIMALS; AVIAN PROTEINS; BINDING SITES; BINDING, COMPETITIVE; CELLS, CULTURED; CHICKENS; CRYSTALLINS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; GENE EXPRESSION REGULATION; GENE SILENCING; GENES, REPORTER; HOMEODOMAIN PROTEINS; LIGHT; MICE; MUTAGENESIS, SITE-DIRECTED; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; OLIGONUCLEOTIDES; OPSIN; PINEAL GLAND; PROMOTER REGIONS (GENETICS); REGULATORY SEQUENCES, NUCLEIC ACID; REPRESSOR PROTEINS; TRANSCRIPTION FACTORS;

EID: 0036615853     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.22-11-04357.2002     Document Type: Article

References (34)

1. Akiyama M, Kouzu Y, Takahashi S, Wakamatsu H, Moriya T, Maetani M, Watanabe S, Tei H, Sakaki Y, Shibata S (1999) Inhibition of light- or glutamate-induced mPer1 expression represses the phase shifts into the mouse circadian locomotor and suprachiasmatic firing rhythms. J Neurosci 19:1115-1121.
2. Albrecht U, Sun ZS, Eichele G, Lee CC (1997) A differential response of two putative mammalian circadian regulators, mper1 and mper2, to light. Cell 91:1055-1064.
3. Chattopadhyay S, Ang LH, Puente P, Deng XW, Wei N (1998) Arabidopsis bZIP protein HY5 directly interacts with light-responsive promoters in mediating light control of gene expression. Plant Cell 10:673-683.
4. Crosio C, Cermakian N, Allis CD, Sassone-Corsi P (2000) Light induces chromatin modification in cells of the mammalian circadian clock. Nat Neurosci 3:1241-1247.
5. Deguchi T (1981) Rhodopsin-like photosensitivity of isolated chicken pineal gland. Nature 290:706-707.
6. Doi M, Nakajima Y, Okano T, Fukada Y (2001) Light-induced phase-delay of the chicken pineal circadian clock is associated with the induction of cE4bp4, a potential transcriptional repressor of cPer2 gene. Proc Natl Acad Sci USA 98:8089-8094.
7. Donald RG, Cashmore AR (1990) Mutation of either G box or I box sequences profoundly affects expression from the Arabidopsis rbcS-1A promoter. EMBO J 9:1717-1726.
8. Funahashi J, Sekido R, Murai K, Kamachi Y, Kondoh H (1993) δ-crystallin enhancer binding protein δEF1 is a zinc finger-homeodomain protein implicated in postgastrulation embryogenesis. Development 119:433-446.
9. Furukawa T, Morrow EM, Cepko CL (1997) Crx, a novel otx-like homeobox gene, shows photoreceptor-specific expression and regulates photoreceptor differentiation. Cell 91:531-541.
10. Gekakis N, Staknis D, Nguyen HB, Davis FC, Wilsbacher LD, King DP, Takahashi JS, Weitz CJ (1998) Role of the CLOCK protein in the mammalian circadian mechanism. Science 280:1564-1569.
11. Genetta T, Ruezinsky D, Kadesch T (1994) Displacement of an E-box-binding repressor by basic helix-loop-helix proteins: implications for B-cell specificity of the immunoglobulin heavy-chain enhancer. Mol Cell Biol 14:6153-6163.
12. Gorski K, Carneiro M, Schibler U (1986) Tissue-specific in vitro transcription from the mouse albumin promoter. Cell 47:767-776.
13. Hao HL, Allen D, Hardin PE (1997) A circadian enhancer mediates PER-dependent mRNA cycling in Drosophila melanogaster. Mol Cell Biol 17:3687-3693.
14. Heintzen C, Loros JJ, Dunlap JC (2001) The PAS protein VIVID defines a clock-associated feedback loop that represses light input, modulates gating, and regulates clock resetting. Cell 104:453-464.
15. Hida A, Koike N, Hirose M, Hattori M, Sakaki Y, Tei H (2000) The human and mouse Period1 genes: five well-conserved E-boxes additively contribute to the enhancement of mPer1 transcription. Genomics 65:224-233.
16. Jin X, Shearman LP, Weaver DR, Zylka MJ, de Vries GJ, Reppert SM (1999) A molecular mechanism regulating rhythmic output from the suprachiasmatic circadian clock. Cell 96:57-68.
17. Kamachi Y, Kondoh H (1993) Overlapping positive and negative regulatory elements determine lens-specific activity of the δ1-crystallin enhancer. Mol Cell Biol 13:5206-5215.
18. King DP, Takahashi JS (2000) Molecular genetics of circadian rhythms in mammals. Annu Rev Neurosci 23:713-742.
19. Korenbrot JI, Fernald RD (1989) Circadian rhythm and light regulate opsin mRNA in rod photoreceptors. Nature 337:454-457.
20. Li X, Chen S, Wang Q, Zack DJ, Snyder SH, Borjigin J (1998) A pineal regulatory element (PIRE) mediates transactivation by the pineal/ retina-specific transcription factor CRX. Proc Natl Acad Sci USA 95:1876-1881.
21. Martínez-García JF, Huq E, Quail PH (2000) Direct targeting of light signals to a promoter element-bound transcription factor. Science 288:859-863.
22. McGinnis JF, Austin BL, Stepanik PL, Lerious V (1994) Light-dependent regulation of the transcriptional activity of the mammalian gene for arrestin. J Neurosci Res 38:479-482.
23. McWatters H, Dunlap JC, Millar AJ (1999) Circadian biology: clocks for the real world. Curr Biol 9:R633-R635.
24. Okano T, Yoshizawa T, Fukada Y (1994) Pinopsin is a chicken pineal photoreceptive molecule. Nature 372:94-97.
25. Okano T, Yamamoto K, Okano K, Hirota T, Kasahara T, Sasaki M, Takanaka Y, Fukada Y (2001) Chicken pineal clock genes: implication of BMAL2 as a bidirectional regulator in circadian clock oscillation. Genes Cells 6:825-836.
26. Pando MP, Sassone-Corsi P (2001) Molecular clocks: a vivid loop of light. Nature 410:311-313.
27. Rehemtulla A, Warwar R, Kumar R, Ji X, Zack DJ, Swaroop A (1996) The basic motif-leucine Zipper transcription factor Nrl can positively regulate rhodopsin gene expression. Proc Natl Acad Sci USA 93:191-195.
28. Shearman LP, Zylka MJ, Weaver DR, Kolakowski Jr LF, Reppert SM (1997) Two period homologs: circadian expression and photic regulation in the suprachiasmatic nuclei. Neuron 19:1261-1269.
29. Shigeyoshi Y, Taguchi K, Yamamoto S, Takekida S, Yan L, Tei H, Moriya T, Shibata S, Loros JJ, Dunlap JC, Okamura H (1997) Light-induced resetting of a mammalian circadian clock is associated with rapid induction of the mPer1 transcript. Cell 91:1043-1053.
30. Steenhard BM, Besharse JC (2000) Phase shifting the retinal circadian clock: xPer2 mRNA induction by light and dopamine. J Neurosci 20:8572-8577.
31. Takanaka Y, Okano T, Iigo M, Fukada Y (1998) Light-dependent expression of pinopsin gene in chicken pineal gland. J Neurochem 70:908-913.
32. Terzaghi WB, Cashmore AR (1995) Light-regulated transcription. Annu Rev Plant Physiol Plant Mol Biol 5:445-475.
33. Yu W, Nomura M, Ikeda M (2002) Interactivating feedback loops within the mammalian clock: BMAL1 is negatively autoregulated and upregulated by CRY1, CRY2, and PER2. Biochem Biophys Res Commun 290:933-941.
34. Zatz M, Mullen DA, Moskal JR (1988) Photoendocrine transduction in cultured chick pineal cells: effects of light, dark, and potassium on the melatonin rhythm. Brain Res 438:199-215.