Synthesis and characterization of pregabalin lactose conjugate degradation products

Journal of Pharmaceutical and Biomedical Analysis

Volumn 28, Issue 5, 2002, Pages 917-924

  Lovdahl, Michael J ^a   Hurley, Timothy R ^a   Tobias, Brian ^a   Priebe, Stephen R ^a  

^a PFIZER INC   (United States)

Author keywords

Amadori rearrangement; HPLC; LC MS MS; Malliard; Pharmaceutical analysis; Pregabalin

Indexed keywords

LACTOSE; PREGABALIN;

AMADORI REARRANGEMENT; ARTICLE; CHEMICAL ANALYSIS; CHEMICAL REACTION; DEGRADATION; GLYCATION; HEATING; ISOLATION PROCEDURE; LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; SPECTROSCOPY; SYNTHESIS;

ANTICONVULSANTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GAMMA-AMINOBUTYRIC ACID; LACTOSE; MAGNETIC RESONANCE SPECTROSCOPY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 0036605361     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0731-7085(01)00710-5     Document Type: Article

References (5)

1. Pharmaceutical formulation instability and the Maillard reaction
2. Maillard reaction of lactose and fluoxetine hydrochloride, a secondary amine