Cisplatin, tegafur, and leucovorin: A moderately effective and minimally toxic outpatient neoadjuvant chemotherapy for locally advanced squamous cell carcinoma of the head and neck

Cancer

Volumn 94, Issue 11, 2002, Pages 2989-2995

  Wang, Hung Ming ^a   Wang, Cheng Su ^a   Chen, Jen Shi ^a   Chen, I How ^a   Liao, Chun Ta ^a   Chang, Tung Chieh Joseph ^a  

^a CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

Author keywords

Chemotherapy; Head and neck neoplasms; Squamous cell carcinoma; Tegafur

Indexed keywords

CISPLATIN; FOLINIC ACID; TEGAFUR;

ADJUVANT CHEMOTHERAPY; ADULT; AGED; ANEMIA; ARTICLE; CANCER COMBINATION CHEMOTHERAPY; DIARRHEA; DRUG EFFICACY; FEMALE; HEAD AND NECK CARCINOMA; HUMAN; KIDNEY DISEASE; LEUKOPENIA; MAJOR CLINICAL STUDY; MALE; OUTPATIENT DEPARTMENT; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA; STOMATITIS; THROMBOCYTOPENIA; VOMITING; WORLD HEALTH ORGANIZATION;

ADMINISTRATION, ORAL; ADULT; AGED; AMBULATORY CARE FACILITIES; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CARCINOMA, SQUAMOUS CELL; CISPLATIN; HEAD AND NECK NEOPLASMS; HUMANS; INFUSIONS, INTRAVENOUS; LEUCOVORIN; MALE; MIDDLE AGED; NEOADJUVANT THERAPY; NEOPLASM STAGING; TEGAFUR; TREATMENT OUTCOME;

EID: 0036604356     PISSN: 0008543X     EISSN: None     Source Type: Journal    
DOI: 10.1002/cncr.10570     Document Type: Article

References (46)

1. Another look at induction chemotherapy for organ preservation in patients with head and neck cancer
2. Head and neck cancer in 1994: A change in the standard of care
3. Induction chemotherapy plus radiation compared with surgery plus radiation in patients with advanced laryngeal cancer
4. Larynx preservation in pyriform sinus cancer: Preliminary results of a European Organization for Research and Treatment of Cancer phase III trial
5. Intensive induction chemotherapy and radiation for organ preservation in patients with advanced resectable head and neck carcinoma
6. Laryngeal preservation by induction chemotherapy plus radiotherapy in locally advanced head and neck cancer: The M.D. Anderson Cancer Center experience
7. Organ-function preservation in advanced oropharyngeal cancer: Results with induction chemotherapy and radiation
8. Phase III trial of initial chemotherapy in stage III or IV head and neck cancers: A study by the Gruppo di Studio sui Tumori della Testa e del collo
9. The impact of betel quid chewing on the chemotherapy-induced mucositis of the head and neck cancer in betel quid chewing prevalent area
10. Cisplatin and 5-Fluorouracil as neoadjuvant chemotherapy: Predicting response in head and neck squamous cell cancer
11. A review of the United States clinical experience of the fluoropyrimidine, tegafur (NSC 148958)
12. Phase II study of fluorouracil and its modulation in advanced colorectal cancer: A Southwest Oncology Group study
13. A prospective randomized comparison of continuous infusion fluorouracil with a conventional bolus schedule in metastatic colorectal carcinoma: A Mid-Atlantic Oncology Program study
14. Tissue concentration of tegafur suppository in patients with head and neck cancer - Concentration of 5-FU in cancer tissue
15. A phase II study of Futraful suppository in head and neck cancer
16. Phase II trial of cisplatin and tegafur as initial therapy in squamous cell carcinoma of the head and neck
17. Phase II trial of carboplatin and tegafur as induction therapy in squamous cell carcinoma of the head and neck
18. Induction chemotherapy with cisplatin, fluorouracil, and high-dose leucovorin for squamous cell carcinoma of the head and neck: Longterm results
19. Phase II trial of cisplatin, fluorouracil, and pure folinic acid for locally advanced head and neck cancer: A pharmacokinetic and clinical survey
20. Clinical pharmacology of the stereoisomers of leucovorin during repeated oral dosing
21. Pharmacokinetics of leucovorin metabolites in human plasma as a function of dose administered orally and intravenously
22. Clinical experience with tegafur and low dose oral leucovorin: A dose-finding study
23. Guidelines for hospitalization for chemotherapy
24. High-dose versus lowdose cisplatin in advanced head and neck squamous carcinoma: A randomized study
25. Surgical therapy of hypopharyngeal tumors
26. Adjuvant and adjunctive chemotherapy in the management of squamous cell carcinoma of the head and neck region: A meta-analysis of prospective and randomized trials
27. An overview of randomized controlled trials of adjuvant chemotherapy in head and neck cancer
28. Induction chemotherapy followed by concurrent chemoradiation for advanced head and neck cancer: Improved disease control and survival
29. The role of induction chemotherapy in the curative treatment of squamous cell cancer of the head and neck
30. Pharmacokinetics of ftorafur after intravenous and oral administration
31. Oral chemotherapy: Rationale and future directions
32. Patient compliance with oral chemotherapy as assessed by novel electronic technique
33. Carboplatin plus ftorafur as a palliative treatment in locally advanced cancer of the oral cavity and lip
34. Randomized trial of adjuvant chemotherapy with mitomycin plus ftorafur versus mitomycin alone in resected locally advanced gastric cancer
35. Macrocytic anemia as a possible adverse effect of fluoropyrimidines
36. A phase II study of continuous infusion 5-fluorouracil and leucovorin with weekly cisplatin in metastatic colorectal carcinoma
37. Megaloblastic anemia associated with inhibition of thymine synthetasis (observations during 5-fluorouracil treatment)
38. Docetaxel: An effective drug for squamous cell carcinoma of the head and neck
39. Final report of a phase II evaluation of paclitaxel in patients with advanced squamous cell carcinoma of the head and neck: An Eastern Cooperative Oncology Group trial (PA390)
40. A phase II trial of paclitaxel in squamous cell carcinoma of the head and neck with correlative laboratory studies
41. Combination of taxanes with radiation: Preclinical studies
42. Phase II trial of docetaxel, cisplatin, fluorouracil, and leucovorin as induction for squamous cell carcinoma of the head and neck
43. A multicenter phase I-II trial of docetaxel, cisplatin, and fluorouracil induction chemotherapy for patients with locally advanced squamous cell carcinoma of the head and neck
44. A phase II study of combined oral uracil and ftorafur with leucovorin for patients with squamous cell carcinoma of the head and neck