The role of androgen therapy

Best Practice and Research: Clinical Obstetrics and Gynaecology

Volumn 16, Issue 3, 2002, Pages 383-393

  Burger, Henry G ^a,b   Davis, Susan R ^c,d  

^a HUDSON INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b MONASH UNIVERSITY   (Australia)

^c Jean Hailes Foundation   (Australia)

^d MONASH UNIVERSITY   (Australia)

Author keywords

Dehydroepiandrosterone sulphate; Free testosterone; Hypopituitarism; Libido; Premature ovarian failure; Sex hormone binding globulin; Testosterone; Well being

Indexed keywords

ALBUMIN; ANDROGEN; ANDROSTENEDIONE; ESTROGEN; PRASTERONE; PRASTERONE SULFATE; SEX HORMONE; SEX HORMONE BINDING GLOBULIN; TESTOSTERONE;

ACNE; ADRENAL INSUFFICIENCY; ANDROGEN DEFICIENCY; ANDROGEN THERAPY; ESTROGEN THERAPY; FATIGUE; HAIR GROWTH; HAIR LOSS; HUMAN; HYPOPITUITARISM; LETHARGY; LIBIDO DISORDER; OVARY INSUFFICIENCY; PRIORITY JOURNAL; REVIEW; ADULT; AGED; DRUG CONTRAINDICATION; FEMALE; MENOPAUSE; MIDDLE AGED; PATIENT SELECTION; PHYSIOLOGY;

ADULT; AGED; ANDROGENS; ESTROGENS; FEMALE; HUMANS; MENOPAUSE; MIDDLE AGED; PATIENT SELECTION; TESTOSTERONE;

EID: 0036597220     PISSN: 15216934     EISSN: None     Source Type: Journal    
DOI: 10.1053/beog.2001.0281     Document Type: Article

References (34)

1. Davis SR & Burger HG. Androgens and the postmenopausal woman. Journal of Clinical Endocrinology & Metabolism 1996; 81: 2759-2763.
2. Davis SR & Burger HG. The rationale for physiological testosterone replacement in women. Baillière's Clinical Endocrinology and Metabolism 1998; 12: 391-405.
3. Davis SR. Androgen treatment in women. Medical Journal of Australia 1999; 170: 545-549.
4. Yen SSC. In Yen SSC, Jaffe RB & Barbieri RL eds Reproductive Endocrinology, 4th edn. p 479. Philadelphia: W. B. Saunders Company, 1999.
5. Davis SR & Burger HG. The rationale for physiological testosterone replacement in women. Clinical Endoclinology and Metabolism. 1999; 13: 391-406.
6. Orentreich N, Brind JL, Rizer RL et al. Age changes and sex differences in serum dehydroepiandrosterone sulfate concentrations throughout adulthood. Journal of Clinical Endocrinology and Metabolism 1984; 59: 551-555.
7. Burger HG, Dudley EC, Cui J et al. A prospective longitudinal study of serum testosterone, dehydroepiandrosterone sulfate, and sex hormone-binding globulin levels through the menopause transition. Journal of Clinical Endocrinology and Metabolism 2000; 85: 2832-2838.
8. Miller KK, Sesmilo G, Schiller A et al. Androgen deficiency in women with hypopituitarism. Journal of Clinical Endocrinology and Metabolism 2001; 86: 561-567.
9. Zumoff B, Strain GW, Miller LK et al. Twenty-four-hour plasma testosterone concentration declines with age in normal menopausal women. Journal of Clinical Endocrinology and Metabolism 1995; 80: 1429-1430.
10. Mathur RS, Landgreve SC, Moody LO et al. The effect of estrogen treatment on plasma concentrations of steroid hormones, gonadotropins, prolactin and sex hormone-binding globulin in post-menopausal women. Maturitas 1985; 7: 129-133.
11. Simon J, Klaiber E, Wiita B et al. Differential effects of estrogen-androgen and estrogen-only therapy on vasomotor symptoms, gonadotropin secretion and endogenous androgen bioavailability in postmenopausal women. Menopause: The Journal of the American Menopause Society 1999; 6: 138-146.
12. Studd JWW, Colins WP & Chakravarti S. Estradiol and testosterone implants in the treatment of psychosexual problems in postmenopausal women. British Journal of Obstetrics and Gynaecology 1977; 84: 314-315.
13. Sherwin BB, Gelfand MM & Bredner W. Androgen enhances sexual motivation in females: A prospective, crossover study of sexual steroid administration in the surgical menopause. Psychosomatic Medicine 1985; 47: 339-351.
14. Sherwin BB & Gelfand MM. Differential symptom response to parenteral estrogen and/or androgen administration in the surgical menopause. American Journal of Obstetrics and Gynaecology 1985; 151: 153, 160.
15. Burger HG, Hailes J, Menelaus M et al. The management of persistent menopausal symptoms with oestradiol-testosterone implants: Clinical, lipid and hormonal results. Maturitas 1984; 6: 351-358.
16. Burger HG, Hailes J, Nelson J & Menelaus M. Effect of combined implants of estradiol and testosterone on libido in postmenopausal women. British Medical Journal 1987; 294: 936-937.
17. Shiften JL, Braunsten GD, Simon JA et al. Transdermal testosterone treatment in women with impaired sexual function after oophorectomy. New England Journal of Medicine 2000; 343: 682-688.
18. Davis SR, McCloud PI, Strauss BJG et al. Testosterone enhances estradiol's effects on postmenopausal bone density and sexuality. Maturitas 1995; 21: 227-236.
19. Arlt W, Callies F, Van Vlijmen JC et al. Dehydroepiandrosterone replacement in women with adrenal insufficiency. New England Journal of Medicine 1999; 341: 1013-1020.
20. Raisz LG, Wiita B, Artis A et al. Comparison of the effects of estrogen alone and estrogen plus androgen on biochemical markers on bone formation and resorption in postmenopausal women. Journal of Clinical Endocrinology and Metabolism 1996; 81: 37-43.
21. Watts JB, Notelovitz M, Timmons MC et al. Comparison of oral estrogens and estrogens plus androgen on bone mineral density, menopausal symptoms, and lipid-lipoprotein profiles in surgical menopause. Obstetrics and Gynecology 1995; 85: 529-537.
22. Bachmann G, Bancroft J, Braunstein G et al. Female androgen insufficiency: the Princeton consensus statement on definition, classification and assessment. Fertility and Sterility 77: 2002; 660-665.
23. Kaplan HS & Owett T. The female androgen deficiency syndrome. Journal of Sex and Marital Therapy 1993; 19: 3-24.
24. Bachmann GA, Leiblum SR, Kemmann E et al. Sexual expression and its determinants in the postmenopausal woman. Maturitas 1984; 6: 19-29.
25. Cutler WB, Garcia C-R, Huggins GR & Preti G. Sexual behavior and steroid levels among gynecologically premature premenopausal women. Fertility and Sterility 1986; 48: 496-502.
26. Bancroft J, Sherwin B, Alexander GM et al. Oral contraceptives, androgens and the sexuality of young women. II. The role of androgens. Archives of Sexual Behavior 1991; 20: 121-135.
27. Dennerstein L, Dudley EC, Hopper JL et al. A prospective population-based study of menopausal symptoms. Obstetrics and Gynecology 2000; 96: 351-358.
28. Dennerstein L, Randolph J, Taffe J et al. Hormones, mood, sexuality and the menopausal transition (submitted).
29. Kapoor P, Luttrell BM & Williams D. The free androgen index is not valid for males. Journal of Steroid Biochemistry and Molecular Biology 1993; 45: 325-326.
30. Arroyo A, Laughlin GA, Morales AJ & Yen SCC. Inappropriate gonadotropin secretion in polycystic ovary syndrome: influence of adiposity. Journal of Clinical Endocrinology and Metabolism 1997; 82: 3728-3733.
31. Lobo RA. Androgens in postmenopausal women: production, possible role and replacement options. Obstetrical and Gynecological Survey 2001; 56: 361-376.
32. Buckler HM, Robertson WR & Wu FCW. Which androgen replacement therapy for women? Journal of Clinical Endocrinology and Metabolism 1998; 83: 3920-3924.
33. Rako S. Testosterone deficiency: a key factor in the increased cardiovascular risk to women following hysterectomy or with natural aging? Journal of Women's Health 1998; 7: 825-829.
34. Bemini GP, Sgro M, Moretti A et al. Endogenous androgens and carotid intimal-medial thickness in women. Journal of Clinical Endocrinology & Metabolism 1999; 84: 2008-2012.