Systemic hypertension and obstructive sleep apnoea

Sleep Medicine Reviews

Volumn 6, Issue 3, 2002, Pages 157-173

  Pepperell, Justin C T ^a,b   Davies, Robert J O ^a,b   Stradling, John R ^a,b  

^a OXFORD UNIVERSITY HOSPITALS NHS FOUNDATION TRUST   (United Kingdom)

^b CHURCHILL HOSPITAL   (United Kingdom)

Author keywords

Ambulatory monitoring; Apnoea; Blood pressure; Breathing; Hypertension; Nasal continuous positive airway pressure; Polysomnography; Sleep apnoea; Sleep disordered

Indexed keywords

AMBULATORY MONITORING; ANIMAL MODEL; AROUSAL; AUTONOMIC NERVOUS SYSTEM FUNCTION; BLOOD PRESSURE; BLOOD PRESSURE REGULATION; CARDIOVASCULAR RISK; CIRCADIAN RHYTHM; DISEASE ASSOCIATION; DISEASE SEVERITY; EPIDEMIOLOGICAL DATA; HUMAN; HYPERTENSION; LONGITUDINAL STUDY; NONHUMAN; NOSE BREATHING; POLYSOMNOGRAPHY; POPULATION RESEARCH; POSITIVE END EXPIRATORY PRESSURE; REVIEW; SLEEP APNEA SYNDROME; SLEEP DISORDER;

EID: 0036592150     PISSN: 10870792     EISSN: None     Source Type: Journal    
DOI: 10.1053/smrv.2001.0189     Document Type: Article

References (72)

1. Levinson PD, Millman RP. Causes and consequences of blood pressure alterations in obstructive sleep apnoea. Arch Intern Med 1991; 151: 455-462.
2. Working group on OSA and hypertension, Carlson J, Davies R, Ehlenz K, Grunstein R, Hedner J et al. Obstructive sleep apnoea and blood pressure elevation. What is the relationship? Blood Pressure 1993; 2: 166-182.
3. Olson LG, King MT, Hensley MJ, Saunders NA. A community study of snoring and sleep-disordered breathing. Prevalence. Am J Respir Crit Care Med 1995; 152: 711-716.
4. Young T, Palta M, Dempsey J, Skatrud J, Weber S, Badr S. The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med 1993; 328: 1230-1235.
5. MacMahon S, Peto R, Cutler J, Collins R, Sorlie P, Neaton J et al. Blood pressure, stroke,and coronary heart disease. Part I, prolonged differences in blood pressure: prospective observational studies corrected for the regression dilution bias. Lancet 1990; 335: 765-774.
6. Collins R, Peto R, MacMahon S, Hebert P, Fiebach NH, Eberlein KA et al. Blood pressure, stroke, and coronary heart disease. Part2, short-term reductions in blood pressure: overview of randomised drug trials in the epidemiological context. Lancet 1990; 335: 827-838.
7. Pickering TG. Strategies for the evaluation and treatment of hypertension and some implications of blood pressure variability. Circulation 1987; 76(suppl I): 77-83.
8. Verdecchia P. Prognostic Value of Ambulatory Blood Pressure Current Evidence and Clinical Implications. Hypertension 2000; 35: 844-851.
9. Lip GY, Zarifis J, Farooqi IS, Page A, Sagar G, Beevers DG. Ambulatory Blood Pressure Monitoring in Acute Stroke. The West Birmingham Stroke Project. Stroke 1997; 28: 31-35.
10. Verdecchia P, Schillaci G, Borgioni C, Ciucci A, Gattobigio R, Comparato E. Altered circadian blood pressure profile and prognosis. Blood Press Monitoring 1997; 2: 347-352.
11. Suzuki M, Guilleminault C, Otsuka K, Shiomi T. Blood pressure "dipping" and "non-dipping" in obstructive sleep apnoea syndrome patients. Sleep 1996; 19: 382-387.
12. Davies RJO, Vardi-Visy K, Clarke M, Stradling JR. Identification of sleep disruption and sleep dis-ordered breathing from the systolic blood pressure profile. Thorax 1993; 48: 1242-1247.
13. Heude E, Bourgin P, Feigel P, Escourrou P. Ambulatory monitoring of blood pressure disturbs sleep and raises systolic pressure at night in patients suspected of suffering from sleep-disordered breathing. Clin Sci Colch 1996; 91: 45-50.
14. O'Brien E, Sheridan J, O'Malley K. Dippers and non-dippers. Lancet 1988; 2: 397.
15. Isaksson H, Svanborg E. Obstructive sleep apnoea syndrome in male hypertensives, refractory to drug therapy. Nocturnal automatic blood pressure measurements - An aid to diagnosis? Clin Exp Hypertens A 1991; 13: 1195-1212.
16. Wright J, Johns R, Watt I, Melville A, Sheldon T. Health effects of obstructive sleep apnoea and the effectiveness of continuous positive airways pressure: A systematic review of the research evidence. Br Med J 1997; 314: 851-860.
17. Weinsier RL, Norris DJ, Birch R, Bernstein RS, Wang J, Yang M et al. The relative contribution of body fat and fat pattern to blood pressure level. Hypertension 1984; 7: 578-585.
18. Levinson PD, McGarvey ST, Carlisle CC, Eveloff SE, Herbert PN, Millman RP. Adiposity and cardiovascular risk factors in men with obstructive sleep apnoea. Chest 1993; 103: 1336-1342.
19. Bardwell WA, Ziegler MG, Ancoli-Israel S, Berry CC, Nelesen RA, Durning A et al. Does caffeine confound relationships among adrenergic tone, blood pressure and sleep apnoea? [In Process Citation]. J Sleep Res 2000; 9: 269-272.
20. Robertson D, Frolich JC, Carr RK, Watson JT, Hollifield JW, Shand DG et al. Effects of caffeine on plasma renin activity, catecholamines and blood pressure. N Engl J Med 1978; 298: 181-186.
21. Prybylski J, Sabbah HN, Stein PD. Why do patients with essential hypertension experience sleep apnoea syndrome? Medical Hypothesis 1980; 20: 173-177.
22. Davies RJO, Kendrick A, Wiltshire N, Catterall J, Crosby J, Stradling JR. The effect of regression dilution bias on the nocturnal hypoxaemia v blood pressure relationship. Thorax December 1996 B.T.S. 1996.
23. Stradling JR, Barbour C, Glennon J, Langford BA, Crosby JH. Which aspects of breathing during sleep influence the overnight fall of blood pressure in a community population. Thorax 2000; 55: 393-398.
24. Bennett LS, Langford BA, Stradling JR, Davies RJO. Sleep fragmentation indices as predictors of daytime sleepiness and nCPAP response in OSA. Am J Respir Crit Care Med 1998; 158: 778-786.
25. van den Aardweg JG, Karemaker JM. Repetitive apnoeas induce periodic hypertension in normal subjects through hypoxia. J Appl Physiol 1992; 72: 821-827.
26. Hardy JC, Gray K, Whisler S, Leuenberger U. Sympathetic and blood pressure responses to voluntary apnoea are augmented by hypoxemia. J Appl Physiol 1994; 77: 2360-2365.
27. Morgan BJ, Denahan T, Ebert TJ. Neurocirculatory consequences of negative intrathoracic pressure vs. asphyxia during voluntary apnoea. J Appl Physiol 1993; 74: 2969-2975.
28. Katragadda S, Xie A, Puleo D, Skatrud JB, Morgan BJ. Neural mechanism of the pressor response to obstructive and nonobstructive apnoea. J Appl Physiol 1997; 83: 2048-2054.
29. Leuenberger UA, Jacob E, Sweer L, Waravdekar N, Zwillich C, Sinoway L. Surges of muscle sympathetic nerve activity during obstructive apnoea are linked to hypoxemia. J Appl Physiol 1995; 79: 581-588.
30. Smith ML, Niedermaier ON, Hardy SM, Decker MJ, Strohl KP. Role of hypoxemia in sleep apnoea-induced sympathoexcitation. J Auton Nerv Syst 1996; 56: 184-190.
31. Ringler J, Basner RC, Shannon R, Schwartzstein R, Manning H, Weinberger SE et al. Hypoxemia alone does not explain blood pressure elevations after obstructive apnoeas. J Appl Physiol 1990; 69: 2143-2148.
32. Davies RJO, Belt PJ, Robert SJ, Ali NJ, Stradling JR. Arterial blood pressure responses to graded transient arousal from sleep in normal humans. J Appl Physiol 1993; 74: 1123-1130.
33. Morgan BJ, Crabtree DC, Puleo DS, Badr MS, Toiber F, Skatrud JB. Neurocirculatory consequences of abrupt change in sleep state in humans. J Appl Physiol 1996; 80: 1627-1636.
34. Ringler J, Garpestad E, Basner RC, Weiss JW. Systemic blood pressure elevation after airway occlusion during NREM sleep. Am J Respir Crit Care Med 1994; 150: 1062-1066.
35. Morgan BJ, Crabtree DC, Palta M, Skatrud JB. Combined hypoxia and hypercapnia evokes longlasting sympathetic activation in humans. J Appl Physiol 1995; 79: 205-213.
36. Carlson JT, Hedner J, Elam M, Ejnell H, Sellgren J, Wallin BG. Augmented resting sympathetic activity in awake patients with obstructive sleep apnoea. Chest 1993; 103: 1763-1768.
37. Narkiewicz K, van de Borne PJ, Montano N, Dyken ME, Phillips BG, Somers VK. Contribution of tonic chemoreflex activation to sympathetic activity and blood pressure in patients with obstructive sleep apnoea. Circulation 1998; 97: 943-945.
38. Brooks D, Horner RL, Kozar LF, Render Teixeira CL, Phillipson EA. Obstructive sleep apnoea as a cause of systemic hypertension. Evidence from a canine model. J Clin Invest 1997; 99: 106-109.
39. Carlson JT, Hedner JA, Sellgren J, Elam M, Wallin BG. Depressed baroreflex sensitivity in patients with obstructive sleep apnoea. Am J Respir Crit Care Med 1996; 154: 1490-1496.
40. Ehlenz K, Peter JH, Kaffarnik H, von Wichert P. Disturbance in volume-regulating hormone systems: a key to the pathogenesis of hypertension in obstructive sleep apnoea? Pneumologie 1991; 45(Suppl): 239-245.
41. Saarelainen S, Hasan J, Siitonen S, Seppala E. Effect of nasal CPAP treatment on plasma volume, aldosterone and 24-h blood pressure in obstructive sleep apnoea. J Sleep Res 1996; 5: 181-185.
42. Fletcher EC, Lesske J, Qian W, Miller CC, Unger T. Repetitive, episodic hypoxia causes diurnal elevation of blood pressure in rats [see comments]. Hypertension 1992; 19: 555-561.
43. Fletcher EC, Lesske J, Behm R, Miller CC, Stauss H, Unger T. Carotid chemoreceptors, systemic blood pressure, and chronic episodic hypoxia mimicking sleep apnoea. J Appl Physiol 1992; 72: 1978-1984.
44. Kimoff RJ, Makino H, Horner RL, Kozar LF, Lue F, Slutsky AS et al. Canine model of obstructive sleep apnoea: model description and preliminary application. J Appl Physiol 1994; 76: 1810-1817.
45. Kirby DA, Pinto JM, Weiss JW, Garpestad E, Zinkovska S. Effects of beta adrenergic receptor blockade on hemodynamic changes associated with obstructive sleep apnoea. Physiol Behav 1995; 58: 919-923.
46. O'Donnell CP, King ED, Schwartz AR, Smith PL, Robotham JL. Effect of sleep deprivation on responses to airway obstruction in the sleeping dog. J Appl Physiol 1994; 77: 1811-1818.
47. O'Donnell CP, King ED, Schwartz AR, Robotham JL, Smith PL. Relationship between blood pressure and airway obstruction during sleep in the dog. J Appl Physiol 1994; 77: 1819-1828.
48. Scharf SM, Graver LM, Balaban K. Cardiovascular effects of periodic occlusions of the upper airways in dogs. Am Rev Respir Dis 1992; 146: 321-329.
49. O'Donnell CP, Schwartz AR, Smith PL, Robotham JL, Fitzgerald RS, Shirahata M. Reflex stimulation of renal sympathetic nerve activity and blood pressure in response to apnoea. Am J Respir Crit Care Med 1996; 154: 1763-1770.
50. Fletcher EC, Lesske J, Culman J, Miller CC, Unger T. Sympathetic denervation blocks blood pressure elevation in episodic hypoxia. Hypertension 1992; 20: 612-619.
51. Bao G, Randhawa PM, Fletcher EC. Acute blood pressure elevation during repetitive hypocapnic and eucapnic hypoxia in rats. J Appl Physiol 1997; 82: 1071-1078.
52. Fletcher EC, Bao G, Miller CC3. Effect of recurrent episodic hypocapnic, eucapnic, and hypercapnic hypoxia on systemic blood pressure. J Appl Physiol 1995; 78: 1516-1521.
53. O'Donnell CP, Ayuse T, King ED, Schwartz AR, Smith PL, Robotham JL. Airway obstruction during sleep increases blood pressure without arousal. J Appl Physiol 1996; 80: 773-781.
54. Brooks D, Horner RL, Kimoff RJ, Kozar LF, Render Teixeira CL, Phillipson EA. Effect of obstructive sleep apnoea versus sleep fragmentation on responses to airway occlusion. Am J Respir Crit Care Med 1997; 155: 1609-1617.
55. Parker JD, Brooks D, Kozar LF, Render-Teixeira CL, Horner RL, Douglas BT et al. Acute and chronic effects of airway obstruction on canine left ventricular performance. Am J Respir Crit Care Med 1999; 160: 1888-1896.
56. Bao G, Fletcher EC. Chronic blood pressure changes from recurrent hypoxia in a hypertension prone (FI) rat. Am J Respir Crit Care Med 1995; 151: A754.
57. Nieto FJ. Association of sleep-disordered breathing, sleep apnoea and hypertension in a large community-based study. JAMA 2000; 283: 1829-1836.
58. Peppard PE, Young T, Palta M, Skatrud J. Prospective study of the association between sleep-disordered breathing and hypertension. N Engl J Med 2000; 342: 1378-1384.
59. Stradling JR, Crosby JH. Relation between systemic hypertension and sleep hypoxaemia or snoring: Analysis in 748 men drawn from general practice. Br Med J 1990; 300: 75-78.
60. Hu FB, Willett WC, Colditz GA, Ascherio A, Speizer FE, Rosner B et al. Prospective study of snoring and risk of hypertension in women. Am J Epidemiol 1999; 150: 806-816.
61. Lavie P, Herer P, Hoffstein V. Obstructive sleep apnoea syndrome as a risk factor for hypertension: Population study. BMJ 2000; 320: 479-482.
62. Bixler EO, Vgontzas AN, Lin HM, Ten Have T, Leiby BE, Vela-Bueno A et al. Association of hypertension and sleep-disordered breathing. Arch Intern Med 2000; 160: 2289-2295.
63. Davies CWH, Crosby JH, Mullins RL, Barbour C, Davies RJO, Stradling JR. Case-control study of 24 hour ambulatory blood pressure in patients with obstructive sleep apnoea and normal matched control subjects. Thorax 2000; 55: 736-740.
64. Verdecchia P, Schillaci G, Guerrieri M, Gatteschi C, Benemio G, Boldrini F et al. Circadian blood pressure changes and left ventricular hypertrophy in essential hypertension. Circulation 1990; 81: 528-536.
65. Hedner J, Darpo B, Ejnell H, Carlson J, Caidahl K. Reduction in sympathetic activity after long-term CPAP treatment in sleep apnoea: Cardiovascular implications. Eur Respir J 1995; 8: 222-229.
66. Akashiba T, Kurashina K, Minemura H, Yamamoto H, Horie T. Daytime hypertension and the effects of short-term nasal continuous positive airway pressure treatment in obstructive sleep apnoea syndrome. Intern Med 1995; 34: 528-532.
67. Wilcox I, Grunstein RR, Hedner JA, Doyle J, Collins FL, Fletcher PJ et al. Effect of nasal continuous positive airway pressure during sleep on 24-hour blood pressure in obstructive sleep apnoea. Sleep 1993; 16: 539-544.
68. Engleman HM, Gough K, Martin SE, Kingshott RN, Padfield PL, Douglas NJ. Ambulatory blood pressure on and off continuous positive airway pressure therapy for the sleep apnoea/hypopnea syndrome: Effects in "non-dippers". Sleep 1996; 19: 378-381.
69. Faccenda JF, Mackay TW, Boon NA, Douglas NJ. Randomized placebo-controlled trial of continuous positive airway pressure on blood pressure in the sleep apnoea-hypopnea syndrome. Am J Respir Crit Care Med 2001; 163: 344-348.
70. Becker HF, Jerrentrup A, Ploch T, Grote L, Penzel T, Peter JH. Prospective randomised study on the effects of therapeutic and sub-therapeutic nasal continuous positive airway pressure (NCPAP) treatment on blood pressure in obstructive sleep apnoea (OSA). Am J Respir Crit Care Med 163, A838. 2001.
71. Hla KM, Younge TB, Finn L, Palta M, Skatrud JB. Effect of correction of sleep-disordered breathing on diurnal blood pressure in patients with hypertension. Am J Respir Crit Care Med 2000; 161: A213.
72. Pepperell JCT, Mullins B, Dow SR, Davies RJO, Stradling JR. Blood pressure change after treatment for obstructive sleep apnoea (osa) with continuous positive airway pressure (CPAP). Am J Respir Crit Care Med 2000; 161: A213.