Developmental aspects of immunomodulation: Exploiting the immature immune system for organ transplantation

Transplant Immunology

Volumn 9, Issue 2-4, 2002, Pages 149-153

  West, L J ^a  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD GROUP ANTIGEN; CYTOKINE; MAJOR HISTOCOMPATIBILITY ANTIGEN; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISONE; TACROLIMUS;

BACTERIAL INFECTION; BLOOD GROUP ABO INCOMPATIBILITY; CHILDHOOD DISEASE; CLONAL ANERGY; CONFERENCE PAPER; DONOR; GRAFT REJECTION; HEART TRANSPLANTATION; HEMATOPOIETIC CELL; HUMAN; IMMATURITY; IMMUNOGENICITY; IMMUNOLOGICAL TOLERANCE; IMMUNOMODULATION; IMMUNOSUPPRESSIVE TREATMENT; MOUSE; NEWBORN PERIOD; NONHUMAN; ORGAN TRANSPLANTATION; PRIORITY JOURNAL; SKIN ALLOGRAFT; T LYMPHOCYTE ACTIVATION; AGE; ANIMAL; BLOOD GROUP ABO SYSTEM; BLOOD GROUP INCOMPATIBILITY; HISTOCOMPATIBILITY; IMMUNE SYSTEM; IMMUNOLOGY; INFANT; NEWBORN; PHYSIOLOGY; PRESCHOOL CHILD; REVIEW;

ABO BLOOD-GROUP SYSTEM; AGE FACTORS; ANIMALS; ANIMALS, NEWBORN; BLOOD GROUP INCOMPATIBILITY; CHILD, PRESCHOOL; HUMANS; IMMUNE SYSTEM; IMMUNE TOLERANCE; INFANT; INFANT, NEWBORN; TRANSPLANTATION IMMUNOLOGY;

EID: 0036582006     PISSN: 09663274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0966-3274(02)00044-8     Document Type: Conference Paper

References (52)

1. Immunogenetic consequences of vascular anastomoses between bovine twins
2. Actively acquired tolerance of foreign cells
3. Quantitative studies on tissue transplantation immunity. III: Actively acquired tolerance
4. Quantitative studies on tissue transplantation immunity. IV: Induction of tolerance in newborn mice and studies on the phenomenon of runt disease
5. A discussion on immunological tolerance
6. Neonatal tolerance induction across regions of H-2 complex
7. Neonatal tolerance: Towards an immunogenetic definition of self
8. Neonatal tolerance induction across H-2 mutational disparity: Induction and specificity of tolerance
9. Analysis of neonatally induced tolerance of H-2 alloantigens. I: Adoptive transfer indicates that tolerance of class I and class II antigens is maintained by distinct mechanisms
10. Clonal analysis of helper and effector T-cell function in neonatal transplantation tolerance: Clonal deletion of helper cells determines lack of in vitro responsiveness
11. Tolerance to class II major histocompatibility complex molecules is maintained in the presence of endogenous, interleukin 2-producing, tolerogen-specific T lymphocytes
12. Lymphokine production by MLR-reactive lymphocytes obtained from normal mice and mice rendered tolerant of class II MHC antigens
13. Neonatal tolerance induction by class II alloantigens activates IL-4-secreting, tolerogen-responsive T cells
14. In vitro suppression of cytotoxic T cell generation by lymphocytes from mice rendered neonatally tolerant of class II MHC antigens
15. Neonatal tolerance of H-2 alloantigens: Procuring graft acceptance the 'old-fashioned' way
16. The cellular mechanism of maintenance of neonatally induced tolerance to H-2 class I antigens
17. Neonatally induced transplantation tolerance: In vitro evidence supporting a clonal inactivation mechanism
18. Recirculating, suppressor T cells in transplantation tolerance
19. The involvement of a suppressor mechanism in neonatally induced allograft tolerance in mice
20. Functional clonal deletion in immunological tolerance to major histocompatibility complex antigens
21. Early loss of precursors of CTL and IL2-producing cells in the development of neonatal tolerance to alloantigens
22. Differential susceptibility of cytotoxic and helper T cell precursors to neonatal tolerization to histocompatibility antigens
23. Distinct mechanisms of neonatal tolerance induced by dendritic cells and thymic B cells
24. Enhanced type 2 and diminished type 1 cytokines in neonatal tolerance
25. Fetal liver haematopoietic cells and tolerance to organ allografts
26. Neonatal infusion of allogeneic fetal liver cells induces non-specific acceptance of cardiac allografts without diminution of alloreactivity to skin grafts and in vitro assays
27. Acceptance of third-party cardiac but not skin allografts induced by neonatal exposure to semi-allogeneic lymphohematopoietic cells
28. Defining critical windows in the development of the human immune system
29. Class I and class II anti-HLA antibodies after implantation of cryopreserved allograft material in pediatric patients
30. Bless the babies: One hundred fifteen late survivors of heart transplantation during the first year of life
31. Cardiac transplantation in infancy: Donors and recipients
32. Newborn and infant heart transplantation
33. Immunosuppression for pediatric cardiac transplantation in the modern era
34. Survival after heart transplantation
35. Neonatal immunology
36. Immunologic basis for increased susceptibility of the neonate to infection
37. Potential and limitations of polysaccharide vaccines in infancy
38. Conjugated polysaccharide vaccines
39. The histological distribution of blood-group substances A and B in man
40. Tissular expression of ABH and Lewis antigens in humans and animals: Expected value of different animal models in the study of ABO-incompatible organ transplants
41. Self tolerance to human A and B histo-blood group antigens exists at the B cell level and cannot be broken by potent polyclonal B cell activation in vitro
42. Blood group isoantibody stimulation in man by feeding blood group-active bacteria
43. Developmental patterns of ABO isoagglutinins in normal children correlated with the effects of age, sex, and maternal isoagglutinins
44. Present experience in a series of 26 ABO-incompatible living donor renal allografts
45. Preformed cytotoxic antibodies and ABO-incompatible grafts
46. Progress in and deterrents to orthotopic liver transplantation, with special reference to survival, resistance to hyperacute rejection, and biliary duct reconstruction
47. Liver transplantation across the ABO barrier: The role of plasmapheresis
48. Clinical survey of heart transplantation between ABO blood group-incompatible recipients and donors
49. ABO-incompatible heart transplantation in infants
50. Breaching the barrier of ABO incompatibility in heart transplantation for infants
51. Graft accommodation in infant recipients of ABO-incompatible heart transplants: Donor ABH antigen expression in graft biopsies
52. Deficient isohemagglutinin production following ABO-incompatible infant heart transplantation: Clinical neonatal B cell tolerance?