Epitopes and complementary epitopes of autoantigens: Candidate probes to study and modulate the autoimmune response

Clinical and Experimental Rheumatology

Volumn 20, Issue 3, 2002, Pages 289-291

  Tzioufas, Athanasios G ^a   Moutsopoulos, Haralampos M ^a  

^a UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

Author keywords

Autoantibodies; Complementary peptides; Epitopes; Idiotypes

Indexed keywords

AUTOANTIGEN; EPITOPE;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANTIBODY DETECTION; ANTIGEN BINDING; ANTIGEN STRUCTURE; AUTOIMMUNE DISEASE; BLOOD ANALYSIS; CONTROLLED STUDY; EDITORIAL; EPITOPE MAPPING; GENETIC CODE; HUMAN; IMMUNIZATION; IMMUNOREGULATION; LYMPHOCYTE FUNCTION; MOLECULAR MIMICRY; MOLECULAR PROBE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN STRUCTURE;

AUTOANTIGENS; AUTOIMMUNE DISEASES; EPITOPES; HUMANS; RHEUMATIC DISEASES;

EID: 0036559141     PISSN: 0392856X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Editorial

References (17)

1. The role of autoantibodies in autoimmune disease
2. Fine specificity of the autoimmune response to the Ro/SSA and La/SSB ribonucleoproteins
3. Analysis of B-cell epitopes of the Ro/SS-A autoantigen
4. B-cell epitopes of intracellular autoantigens: Myth and reality
5. The clinical relevance of antibodies to ribosomal-P common epitope in two targeted systemic lupus erythematosus populations: A large cohort of consecutive patients and patients with active central nervous system disease
6. The value of synthetic linear epitope analogues of La/SSB for the detection of autoantibodies to La/SSB; specificity, sensitivity and comparison of methods
7. A major Sm epitope enchored to sequential oligopeptide carriers is a suitable antigenic substrate to detect anti-Sm antibodies
8. Clinical, immunologic and immunogenetic aspects of autoantibody production against Ro/SSA, La/SSB and their linear epitopes in primary Sjögren's syndrome (pSS): A European multicenter study
9. Determinant spreading: Lessons from animal models and human disease
10. Role of intermolecular/intrastructural B- and T-cell determinants in the diversification of autoantibodies to ribonucleoprotein particles
11. Hierarchical self-tolerance to T cell determinants within the ubiquitous nuclear self-antigen La (SS-B) permits induction of systemic autoimmunity in normal mice
12. Study of antibody and T-cell responses in rabbits immunized with synthetic human B cell epitope analogues of La (SSB) autoantigen
13. Preparation and use of complementary peptides
14. Genetic origins of protein shape and interaction rules
15. De novo design of peptides targeted to the EF hands of calmodulin
16. Unmasking the anti-La/SSB response in sera from patients with Sjögren's syndrome by specific blocking of anti-idiotypic antibodies to La/SSB antigenic determinants
17. A new antigen recognized by cytosolic T lymphocytes on a human kidney tumor results from reverse strand transcription