Solute effects on the helix-coil transition

European Physical Journal E

Volumn 7, Issue 4, 2002, Pages 393-396

  Farago, O ^a   Pincus, P ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ELASTOMERS; HYDROGEN BONDS;

HELIX-COIL TRANSITIONS; MELTING TRANSITIONS; POLYPEPTIDE CHAIN; SIMPLE MODELING; SOLUTE EFFECTS; SOLVENT COMPOSITION; SOLVENT EFFECTS; STRUCTURE AND PHYSICAL PROPERTIES;

SOLVENTS;

EID: 0036557104     PISSN: 12928941     EISSN: None     Source Type: Journal    
DOI: 10.1140/epje/i2001-10100-1     Document Type: Article

References (26)

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11. J. Bond, C. Anderson, M.T. Record jr., Biophys. J. 67, 825 (1994); M.C. Williams, J.R. Wenner, I. Rouzina, V.A. Bloomfield, Biophys. J. 80, 874 (2001); I. Rouzina, V.A. Bloomfield, Biophys. J. 80, 894 (2001).
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13. See, e.g., P. Cluzel, A. Lebrun, C. Heller, R. Lavery, J.L. Viovy, D. Chatenay, F. Caron, Science 271, 792 (1996); S.B. Smith, Y. Cui, C. Bustamante, Science 271, 795 (1996); M.C. Williams, J.R. Wenner, I. Rouzina, V.A. Bloomfield, Biophys. J. 80, 1932 (2001).
14. See, e.g., P. Cluzel, A. Lebrun, C. Heller, R. Lavery, J.L. Viovy, D. Chatenay, F. Caron, Science 271, 792 (1996); S.B. Smith, Y. Cui, C. Bustamante, Science 271, 795 (1996); M.C. Williams, J.R. Wenner, I. Rouzina, V.A. Bloomfield, Biophys. J. 80, 1932 (2001).
15. See, e.g., P. Cluzel, A. Lebrun, C. Heller, R. Lavery, J.L. Viovy, D. Chatenay, F. Caron, Science 271, 792 (1996); S.B. Smith, Y. Cui, C. Bustamante, Science 271, 795 (1996); M.C. Williams, J.R. Wenner, I. Rouzina, V.A. Bloomfield, Biophys. J. 80, 1932 (2001).
16. A. Ahsan, J. Rudnick, R. Bruinsma, Biophys. J. 74, 132 (1998); I. Rouzina, V.A. Bloomfield, Biophys. J. 80, 882 (2001). See also the following references that deal with stretching of polypeptides using the same theoretical approach: A. Buhot, A. Halperin, Phys. Rev. Lett. 84, 2160 (2000); M.N. Tamashiro, P. Pincus, Phys. Rev. E 63, 021909 (2001).
17. A. Ahsan, J. Rudnick, R. Bruinsma, Biophys. J. 74, 132 (1998); I. Rouzina, V.A. Bloomfield, Biophys. J. 80, 882 (2001). See also the following references that deal with stretching of polypeptides using the same theoretical approach: A. Buhot, A. Halperin, Phys. Rev. Lett. 84, 2160 (2000); M.N. Tamashiro, P. Pincus, Phys. Rev. E 63, 021909 (2001).
18. A. Ahsan, J. Rudnick, R. Bruinsma, Biophys. J. 74, 132 (1998); I. Rouzina, V.A. Bloomfield, Biophys. J. 80, 882 (2001). See also the following references that deal with stretching of polypeptides using the same theoretical approach: A. Buhot, A. Halperin, Phys. Rev. Lett. 84, 2160 (2000); M.N. Tamashiro, P. Pincus, Phys. Rev. E 63, 021909 (2001).
19. A. Ahsan, J. Rudnick, R. Bruinsma, Biophys. J. 74, 132 (1998); I. Rouzina, V.A. Bloomfield, Biophys. J. 80, 882 (2001). See also the following references that deal with stretching of polypeptides using the same theoretical approach: A. Buhot, A. Halperin, Phys. Rev. Lett. 84, 2160 (2000); M.N. Tamashiro, P. Pincus, Phys. Rev. E 63, 021909 (2001).
20. M. Doi, S.F. Edwards, The Theory of Polymer Dynamics (Oxford University Press, Oxford, 1988). For slightly modified versions of these models see, e.g., J.F. Marko, E.D. Siggia, Macromol. 28, 8759 (1995), or the paper by Smith, Cui and Bustamante in reference [7].
21. M. Doi, S.F. Edwards, The Theory of Polymer Dynamics (Oxford University Press, Oxford, 1988). For slightly modified versions of these models see, e.g., J.F. Marko, E.D. Siggia, Macromol. 28, 8759 (1995), or the paper by Smith, Cui and Bustamante in reference [7].
22. I.V. Soman, A. Karimi, D.A. Case, Biopolymers 31, 1351 (1991); C.A. Schiffer, V. Dötsch, Curr. Opin. Biotechnol. 7, 428 (1996); P. Doruker, I. Bahar, Biophys. J. 72, 2445 (1997); L. D Barron, L. Hecht, G. Wilson, Biochemistry 36, 13143 (1997).
23. I.V. Soman, A. Karimi, D.A. Case, Biopolymers 31, 1351 (1991); C.A. Schiffer, V. Dötsch, Curr. Opin. Biotechnol. 7, 428 (1996); P. Doruker, I. Bahar, Biophys. J. 72, 2445 (1997); L. D Barron, L. Hecht, G. Wilson, Biochemistry 36, 13143 (1997).
24. I.V. Soman, A. Karimi, D.A. Case, Biopolymers 31, 1351 (1991); C.A. Schiffer, V. Dötsch, Curr. Opin. Biotechnol. 7, 428 (1996); P. Doruker, I. Bahar, Biophys. J. 72, 2445 (1997); L. D Barron, L. Hecht, G. Wilson, Biochemistry 36, 13143 (1997).
25. I.V. Soman, A. Karimi, D.A. Case, Biopolymers 31, 1351 (1991); C.A. Schiffer, V. Dötsch, Curr. Opin. Biotechnol. 7, 428 (1996); P. Doruker, I. Bahar, Biophys. J. 72, 2445 (1997); L. D Barron, L. Hecht, G. Wilson, Biochemistry 36, 13143 (1997).
26. In equation (9) we assume that all the new hydrogen bonds are formed at the interfaces between helix and coil domains. This assumption applies to the case when the free-energy gain in creating such a new bond is much larger than the free-energy gain in replacing an existing bond between a coil monomer and a water molecule, with a bond between a coil monomer and impurity.