Nitric oxide facilitates GABAergic neurotransmission in the cat oculomotor system: A physiological mechanism in eye movement control

Journal of Physiology

Volumn 540, Issue 1, 2002, Pages 295-306

  Moreno López, Bernardo ^a   Escudero, Miguel ^b   Estrada, Carmen ^a  

^a UNIVERSITY OF CÁDIZ   (Spain)

^b UNIVERSITY OF SEVILLE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 5 PHOSPHONOVALERIC ACID; 4 AMINOBUTYRIC ACID RECEPTOR; 6 NITRO 7 SULFAMOYLBENZO[F]QUINOXALINE 2,3 DIONE; BICUCULLINE; CYCLIC GMP; FAST BLUE; GLUTAMATE DECARBOXYLASE; GLUTAMATE RECEPTOR; GLYCINE RECEPTOR; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; STRYCHNINE; NITRIC OXIDE SYNTHASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; BRAIN STEM; CAT; CELLULAR DISTRIBUTION; CONTROLLED STUDY; EYE MOVEMENT CONTROL; FEMALE; GABAERGIC TRANSMISSION; HYPOGLOSSAL NUCLEUS; IMMUNOHISTOCHEMISTRY; NERVE FIBER; NERVE PROJECTION; NONHUMAN; NYSTAGMUS; OCULOMOTOR NERVE; PRIORITY JOURNAL; SENSORY NERVE; VELOCITY; VESTIBULAR FUNCTION; VESTIBULAR NUCLEUS; VESTIBULOOCULAR REFLEX; ADULT; ENZYME INHIBITION; EYE MOVEMENT; EYE POSITION; FIRING RATE; NITRERGIC NERVE CELL; OCULOMOTOR SYSTEM;

ABDUCENS NERVE; ANIMALS; BICUCULLINE; BRAIN STEM; CATS; EXCITATORY AMINO ACID ANTAGONISTS; EYE MOVEMENTS; FEMALE; GABA ANTAGONISTS; GAMMA-AMINOBUTYRIC ACID; GLUTAMIC ACID; GLYCINE AGENTS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OCULOMOTOR NERVE; QUINOXALINES; REFLEX, VESTIBULO-OCULAR; STRYCHNINE; SYNAPTIC TRANSMISSION;

EID: 0036554805     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1113/jphysiol.2001.013308     Document Type: Article

References (50)

1. ARIANO, M. A., LEWICKI, J. A., BRANDWEIN, J. H. & MURAD, F. (1982). Immunohistochemical localization of guanylate cyclase within neurons of rat brain. Proceedings of the National Academy of Sciences of the USA 79,1316-1320.
2. ARNOLD, D. B., ROBINSON, D. A. & LEIGH, R. J. (1999). Nystagmus induced by pharmacological inactivation of the brainstem ocular motor integrator in monkey. Vision Research 39, 4286-4295.
3. BAKER, R. & BERTHOZ, A. (1975). Is the prepositus hypoglossi nucleus the source of another vestibulo-ocular pathway.? Brain Research 86, 121-127.
4. BAKER, R., MANO, N. & SHIMAZU, H. (1969). Postsynaptic potentials in abducens motoneurons induced by vestibular stimulation. Brain Research 15, 577-580.
5. BATSCHELET, E. (1981). Circular Statistics in Biology. Academic Press.
6. BERMAN, A. L (1968). The Brain Stem of the Cat: a Cytoarchitectonic Atlas with Stereotaxic Coordinates. The University of Wisconsin Press, Madison, WI, USA.
7. BERTHOZ, A., DROULEZ, J., VIDAL, P. P. & YOSHIDA, K. (1989). Neural correlates of horizontal VOR cancelation during rapid eye movements in the cat. Journal of Physiology 419, 717-751.
8. BREDT, D. S. & SNYDER, S. H. (1989). Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum. Proceedings ofthe National Academy of Sciences of the USA 86, 9030-9033.
9. CANNON, S. C. & ROBINSON, D. A. (1987). Loss of the neural integrator of the oculomotor system from brain stem lesions in monkey. Journal of Neurophysiology 57, 1383-1409.
10. CHERON, G., GILLIS, P. & GODAUX, E. (1986a). Lesion in the cat prepositus complex: effects on the optokinetic system. Journal of Physiology 372, 95-111.
11. CHERON, G. & GODAUX, E. (1987). Disabling ofthe oculomotor neural integrator by kainic acid injections in the prepositus vestibular complex of the cat. Journal of Physiology 394, 267-290.
12. CHERON, G., GODAUX, E., LAUNE, J. M. & VANDERKELER, B. (1986b). Lesions in the cat prepositus complex: effects on the vestibulo-ocular reflex and saccades. Journal of Physiology 372, 75-94.
13. DE LA CRUZ, R. R., ESCUDERO, M., & DELGADO-GARCÍA, J. M. (1990). Behavior of medial rectus motoneurons in the alert cat. European Journal of Neuroscience 1, 288-295.
14. DELGADO-GARCÍA, J. M., DEL POZO, F. & BAKER, R. (1986). Behavior of neurons in the abducens nucleus of the alert cat. I. Motoneurons. Neuroscience 17, 929-952.
15. DELGADO-GARCÍA, J. M., VIDAL, P. P., GÓMEZ, C. & BERTHOZ, A. (1989). A neurophysiological study of prepositus hypoglossi neurons projecting to oculomotor and preoculomotor nuclei in the alert cat. Neuroscience 29, 291-307.
16. ESCUDERO, M., DE LA CRUZ, R. R. & DELGADO-GARCÍA, J. M. (1992). A physiological study of vestibular and prepositus hypoglossi neurones projecting to the abducens nucleus in the alert cat. Journal of Physiology 458, 539-560.
17. ESCUDERO, M. & DELGADO-GARCÍA, J. M. (1988). Behavior of reticular, vestibular and prepositus neurons terminating in the abducens nucleus ofthe alert cat. Experimental Brain Research 71, 218-222.
18. FEDELE, E. & RAITERI, M. (1999). In vivo studies of cerebral glutamate receptor/NO/cGMP pathway. Progress in Neurobiology 58, 89-120.
19. FLANDRIN, J. M., COURJON, J. H., JEANNEROD, M. & SCHMID, R. (1983) Effects of unilateral flocculus lesions on vestibulo-ocular responses in the cat. Neuroscience 8, 809-817.
20. FUCHS, A. F. & LUSCHEI, E. S. (1970). Firing patterns ofabducens neurons of alert monkeys in relationship to horizontal eye movement. Journal of Neurophysiology 33, 382-392.
21. FUCHS, A. F. & ROBINSON, D. A. (1966). A method for measuring horizontal and vertical eye movement chronically in the monkey. Journal of Applied Physiology 21, 1068-1070.
22. FUKUSHIMA, K., KANEKO, C. R. S. & FUCHS, A. F. (1992). The neuronal substrate of integration in the oculomotor system. Progress in Neurobiology 39, 609-639.
23. GODAUX, E. & CHERON, G. (1996). The hypothesis of the uniqueness of the oculomotor neural integrator: direct experimental evidences in the cat. Journal of Physiology 492, 517-527.
24. GODAUX, E., METTENS, P. & CHERON, G. (1993). Differential effect of injections of kainic acid into the prepositus and the vestibular nuclei of the cat. Journal of Physiology 472,459-482.
25. HENN, V. & COHEN, B. (1973). Quantitative analysis of activity in eye muscle motoneurons during saccadic eye movements and position of fixation. Journal of Neurophysiology 36, 115-126.
26. HIKOSAKA, O., IGUSA, Y. & IMAI, H. (1980). Inhibitory connections of nystagmus-related reticular burst neurons in the abducens, prepositus hypoglossi and vestibular nuclei in the cat. Experimental Brain Research 39, 301-311.
27. HIKOSAKA, O., IGUSA, Y., NAKAO, S. & SHIMAZU, H. (1978). Direct inhibitory synaptic linkage of pontomedullary reticular burst neurons with abducens motoneurons in the cat. Experimental Brain Research 33, 337-352.
28. HOLSTEIN, G. R., MARTINELLI, G. P., DEGEN, J. W. & COHEN, B. (1996). GABAergic neurons in the primate vestibular nuclei. Annals of the New York Academy of Sciences 781, 443-457.
29. KANEKO, C. R. S. (1997). Eye movement deficits following ibotenic acid lesions of the nucleus prepositus hypoglossi in monkeys. I. Saccades and fixations. Journal of Neurophysiology 78, 1753-1768.
30. KANEKO, C. R. S., EVINGER, C. & FUCHS, A. F. (1981). Role of cat pontine burst neurons in generation of saccadic eye movements. Journal of Neurophysiology 46, 387-408.
31. LÓPEZ-BARNEO, J., DARLOT, C., BERTHOZ, A. & BAKER, R (1982). Neuronal activity in prepositus; nucleus correlated with eye movement in the alert cat. Journal of Neurophysiology 47, 329-352.
32. MCCREA, R. A. & BAKER, R. (1985). Anatomical connections of the nucleus prepositus of the cat. Journal of Comparative Neurology 237, 377-407.
33. MCCREA, R. A., YOSHIDA, K., BERTHOZ, A. & BAKER, R. (1980). Eye movements related activity and morphology of second order vestibular neurons terminating in the cat abducens nucleus. Experimental Brain Research 40, 468-473.
34. MCFARLAND, J. L. & FUCHS, A. F. (1992). Discharge patterns in nucleus prepositus hypoglossi and adjacent medial vestibular nucleus during horizontal eye movements in behaving macaques. Journal of Neurophysiology 68, 319-332.
35. METTENS, P., CHERON, G. & GODAUX, E. (1994a). NMDA receptors are involved in temporal integration in the oculomotor system of the cat. NeuroReport 5, 1333-1336.
36. METTENS, P., CHERON, G. & GODAUX, E. (1994b). Role of the vestibular commisure in gaze-holding in the cat:a pharmacological evaluation. NeuroReport 5, 1421-1424.
37. METTENS, P., GODAUX, E., CHERON, G. & GALIANA, H. L. (1994c). Effect of muscimol microinjection into the prepositus hypoglossi and the medial vestibular nuclei on cat eye movements. Journal of Neurophysiology 72, 785-802.
38. MONTAGUE, P. R., GANCAYCO, C. D., WINN, M. J., MARCHASE, R. B. & FRIEDLANDER, M. J. (1994). Role of NO production in NMDA receptor-mediated neurotransmitter release in cerebral cortex. Science 263, 973-977.
39. MORENO-LÓPEZ, B., ESCUDERO, M., DELGADO-GARCÍA, J. M. & ESTRADA, C. (1996). Nitric oxide production by brain stem neurons is required for normal performance of eye movements in alert animals. Neuron 17, 739-745.
40. MORENO-LÓPEZ, B., ESCUDERO, M., DE VENTE, J. & ESTRADA, C. (2001). Morphological identification of nitric oxide sources and targets in the cat oculomotor system. Journal of Comparative Neurology 435, 311-324.
41. MORENO-LÓPEZ, B., ESTRADA, C. & ESCUDERO, M. (1998). Mechanisms of action and targets of nitric oxide in the oculomotor system. Journal of Neuroscience 18, 10672-10679.
42. PRECHT, W., SCHWINDT, P. C. & BAKER, R. (1973). Removal of vestibular commisural inhibition by antagonists of GABA and glycine. Brain Research 62, 222-226.
43. ROBINSON, D. A. (1968). Eye movement control in primates. Science 161, 1219-1224.
44. ROBINSON, D. A. (1975). Oculomotor control signals. In Basic Mechanisms of Ocular Motility and Their Clinical Implications, ed. LENNERSTRAND, G. & BACH-Y-RITA, P., pp. 337-374. Pergamon Press, Oxford.
45. SOUTHAM, E. & GARTHWAITE, J. (1993). The nitric oxide-cyclic GMP signalling pathway in the rat brain. Neuropharmacology 32, 1267-1277.
46. SPENCER, R. F., WEHTHOLD, R. J. & BAKER, R. (1989). Evidence for glycine as an inhibitory neurotransmitter of vestibular, reticular and prepositus hypoglossi neurons that project to the cat abducens nucleus. Journal of Neuroscience 9, 2718-2736.
47. STRASSMAN, A., HIGHSTEIN, S. M. & MCCREA, R. A. (1986a). Anatomy and physiology of saccadic burst neurons in the alert squirrel monkey. I. Excitatory burst neurons. Journal of Comparative Neurology 249, 337-357.
48. STRASSMAN, A., HIGHSTEIN, S. M. & MCCREA, R. A. (1986b). Anatomy and physiology of saccadic burst neurons in the alert squirrel monkey. II. Inhibitory burst neurons. Journal of Comparative Neurology 249, 358-380.
49. TANAKA, J., MARKERINK-VAN ITTERSUM, M., STEINBUSCH, H. W. M. & DE VENTE, J. (1997). Nitric oxide-mediated cGMP synthesis in oligodendrocytes in the developing rat brain. Glia 19, 280-297.
50. YOSHIDA, K., MCCREA, R., BERTHOZ, A. & VIDAL, P. P. (1982). Morphological and physiological characteristics of inhibitory burst neurons controlling horizontal rapid eye movements in the alert cat. Journal of Neurophysiology 48, 761-784.