Immunohistochemical localization of androgen and oestrogen receptors in canine hair follicles

Veterinary Dermatology

Volumn 13, Issue 2, 2002, Pages 113-118

  Bratka Robia, Christine B ^a   Egerbacher, Monika ^a   Helmreich, Magdalena ^a   Mitteregger, Gerda ^a   Benesch, Michael ^b   Bamberg, Elmar ^a  

^a UNIVERSITY OF VETERINARY MEDICINE   (Austria)

^b UNIVERSITY OF VIENNA   (Austria)

Author keywords

Androgen; Canine; Dermal papilla; Dog; Epidermis; Hair follicles; Immunohistochemistry; Oestrogen; Receptor; Steroid

Indexed keywords

CANIS FAMILIARIS;

ANDROGEN RECEPTOR; ESTROGEN RECEPTOR;

ANIMAL; ANIMAL DISEASE; ARTICLE; DOG; FEMALE; HAIR FOLLICLE; IMMUNOHISTOCHEMISTRY; MALE; METABOLISM;

ANIMALS; DOGS; FEMALE; HAIR FOLLICLE; IMMUNOHISTOCHEMISTRY; MALE; RECEPTORS, ANDROGEN; RECEPTORS, ESTROGEN;

EID: 0036551010     PISSN: 09594493     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-3164.2002.00287.x     Document Type: Article

References (16)

1. Rhodes, K.H. Cutaneous manifestations of canine and feline endocrinopathies. Problems in Veterinary Medicine 1990; 2: 617-26.
2. Rosychuk, R.A.W. Cutaneous manifestations of endocrine disease in dogs. Compendium on Continuing Education for the Practising Veterinarian 1998; 20: 287-302.
3. Schmeitzel, L.P., Lothrop, C.D. Jr Hormonal abnormalities in Pomeranians with normal coat and in Pomeranians with growth hormone-responsive dermatosis. Journal of the American Veterinary Medical Association 1990; 197: 1333-41.
4. Bond, R. Hair follicles drive me crazy! Veterinary Dermatology 1999; 10: 81-2.
5. Eicheler, W., Happle, R., Hoffmann, R. 5 Alpha-reductase activity in the human hair follicle concentrates in the dermal papilla. Archives of Dermatological Research 1998; 290: 126-32.
6. Eigenmann, J.E., Poortman, J., Koeman, J.P. Estrogen induced flank alopecia in the female dog: evidence for local rather than systemic hyperestrogenism. Journal of the American Animal Hospital Association 1984; 20: 621-4.
7. Scott, D.W., Miller, W.H. Jr, Griffin, C.E. Sex hormone dermatoses. In: Small Animal Dermatology, 6th edn. Philadelphia: W.B. Saunders, 2001: 827-45.
8. Wallace, M.L., Smoller, B.R. Estrogen and progesterone receptors in androgenic alopecia versus alopecia areata. American Journal of Dermatopathology 1998; 20: 160-3.
9. Oh, H.S., Smart, R.C. An estrogen receptor pathway regulates the telogen-anagen hair follicle transition and influences epidermal cell proliferation. Proceedings of the National Academy of Sciences of the United States of America 1996; 93: 12525-30.
10. Mecklenburg, L. Untersuchungen zur Bedeutung potentieller Haarzyklusmodulatoren in der Haut des Hundes unter besonderer Berücksichtigung endokriner Dermatopathien. Dissertation, vet. med., Tierärztliche Hochschule Hannover, Germany, 1998.
11. Diani, A.R., Mills, C.J. Immunocytochemical localization of androgen receptors in the scalp of the stumptail macaque monkey, a model of androgenetic alopecia. Journal of Investigative Dermatology 1994; 102: 511-14.
12. Shi, R.S., Key, M.E., Karla, K.L. Antigen retrieval in formalin-fixed, paraffin-embedded tissues: an enhancement method for immunohistochemical staining based on microwave oven heating of tissue sections. Journal of Histochemistry and Cytochemistry 1991; 39: 741-8.
13. Choudhry, R., Hodgins, M.B., Van der Kwast, T.H. et al. Localisation of androgen receptors in human skin by immunohistochemistry: implications for the hormonal regulation of hair growth, sebaceous glands and sweat glands. Journal of Endocrinology 1992; 133: 467-75.
14. Paech, K., Webb, P., Kuiper, G.G. et al. Differential ligand activation of estrogen receptors ERalpha and ERbeta at API sites. Science 1997; 277: 1508-10.
15. Randall, V.A. The use of dermal papilla cells in studies of normal and abnormal hair follicle biology. Dermatologic Clinics 1996; 14: 585-94.
16. Sawaya, M.E., Price, V.H. Different levels of 5 alpha-reductase type I and II, aromatase, and androgen receptor in hair follicles of women and men with androgenetic alopecia. Journal of Investigative Dermatology 1997; 109: 296-300.