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Volumn 22, Issue 7, 2002, Pages 2550-2560

Glutamate but Not Glycine Agonist Affinity for NMDA Receptors Is Influenced by Small Cations

Author keywords

Channel activation; Channel gating; Desensitization; Glutamate; Glycine; Ion permeation; NMDA receptor

Indexed keywords

CATION; CESIUM ION; CHOLINE; GLUTAMIC ACID; GLYCINE; GLYCINE RECEPTOR AGONIST; MAGNESIUM; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; POTASSIUM ION; SODIUM; AMINO ACID RECEPTOR BLOCKING AGENT; AMINO ACID RECEPTOR STIMULATING AGENT;

EID: 0036550758     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.22-07-02550.2002     Document Type: Article
Times cited : (12)

References (38)
  • 1
    • 0031961764 scopus 로고    scopus 로고
    • Identification of amino acid residues of the NR2A subunit that control glutamate potency in recombinant NR1/NR2A NMDA receptors
    • Anson LC, Chen PE, Wyllie DJA, Colquhoun D, Schoepfer R (1998) Identification of amino acid residues of the NR2A subunit that control glutamate potency in recombinant NR1/NR2A NMDA receptors. J Neurosci 18:581-589.
    • (1998) J Neurosci , vol.18 , pp. 581-589
    • Anson, L.C.1    Chen, P.E.2    Wyllie, D.J.A.3    Colquhoun, D.4    Schoepfer, R.5
  • 2
    • 0033405289 scopus 로고    scopus 로고
    • Permeant ion regulation of N-methyl-D-aspartate receptor channel block by Mg(2+)
    • Antonov SM, Johnson JW (1999) Permeant ion regulation of N-methyl-D-aspartate receptor channel block by Mg(2+). Proc Natl Acad Sci USA 96:14571-14576.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 14571-14576
    • Antonov, S.M.1    Johnson, J.W.2
  • 3
    • 0032174052 scopus 로고    scopus 로고
    • Binding sites for permeant ions in the channel of NMDA receptors and their effects on channel block
    • Antonov SM, Gmiro VE, Johnson JW (1998) Binding sites for permeant ions in the channel of NMDA receptors and their effects on channel block. Nat Neurosci 1:451-461.
    • (1998) Nat Neurosci , vol.1 , pp. 451-461
    • Antonov, S.M.1    Gmiro, V.E.2    Johnson, J.W.3
  • 4
    • 0033636314 scopus 로고    scopus 로고
    • Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: Crystal structures of the GluR2 ligand binding core
    • Armstrong N, Gouaux E (2000) Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core. Neuron 28:165-181.
    • (2000) Neuron , vol.28 , pp. 165-181
    • Armstrong, N.1    Gouaux, E.2
  • 5
    • 0028915935 scopus 로고
    • Trapping of glutamate and glycine during open channel block of rat hippocampal neuron NMDA receptors by 9-aminoacridine
    • Benveniste M, Mayer ML (1995) Trapping of glutamate and glycine during open channel block of rat hippocampal neuron NMDA receptors by 9-aminoacridine. J Physiol (Lond) 483:367-384.
    • (1995) J Physiol (Lond) , vol.483 , pp. 367-384
    • Benveniste, M.1    Mayer, M.L.2
  • 6
    • 0025082936 scopus 로고
    • A kinetic analysis of the modulation of N-methyl-D-aspartic acid receptors by glycine in mouse cultured hippocampal neurones
    • Benveniste M, Clements J, Vyklicky Jr L, Mayer ML (1990a) A kinetic analysis of the modulation of N-methyl-D-aspartic acid receptors by glycine in mouse cultured hippocampal neurones. J Physiol (Lond) 428:333-357.
    • (1990) J Physiol (Lond) , vol.428 , pp. 333-357
    • Benveniste, M.1    Clements, J.2    Vyklicky Jr., L.3    Mayer, M.L.4
  • 7
    • 0025374796 scopus 로고
    • Concentration-jump experiments with NMDA antagonists in mouse cultured hippocampal neurons
    • Benveniste M, Mienville JM, Sernagor E, Mayer ML (1990b) Concentration-jump experiments with NMDA antagonists in mouse cultured hippocampal neurons. J Neurophysiol 63:1373-1384.
    • (1990) J Neurophysiol , vol.63 , pp. 1373-1384
    • Benveniste, M.1    Mienville, J.M.2    Sernagor, E.3    Mayer, M.L.4
  • 8
    • 0032415129 scopus 로고    scopus 로고
    • Glycine uptake governs glycine site occupancy at NMDA receptors of excitatory synapses
    • Berger AJ, Dieudonne S, Ascher P (1998) Glycine uptake governs glycine site occupancy at NMDA receptors of excitatory synapses. J Neurophysiol 80:3336-3340.
    • (1998) J Neurophysiol , vol.80 , pp. 3336-3340
    • Berger, A.J.1    Dieudonne, S.2    Ascher, P.3
  • 12
    • 0035340978 scopus 로고    scopus 로고
    • Glial transporters for glutamate, glycine, and GABA III. Glycine transporters
    • Gadea A, Lopez-Colome AM (2001) Glial transporters for glutamate, glycine, and GABA III. Glycine transporters. J Neurosci Res 64:218-222.
    • (2001) J Neurosci Res , vol.64 , pp. 218-222
    • Gadea, A.1    Lopez-Colome, A.M.2
  • 13
    • 0029893942 scopus 로고    scopus 로고
    • The glycine binding site of the N-methyl-D-aspartate receptor subunit NR1: Identification of novel determinants of co-agonist potentiation in the extracellular M3-M4 loop region
    • Hirai H, Kirsch J, Laube B, Betz H, Kuhse J (1996) The glycine binding site of the N-methyl-D-aspartate receptor subunit NR1: identification of novel determinants of co-agonist potentiation in the extracellular M3-M4 loop region. Proc Natl Acad Sci USA 93:6031-6036.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 6031-6036
    • Hirai, H.1    Kirsch, J.2    Laube, B.3    Betz, H.4    Kuhse, J.5
  • 14
    • 0024518502 scopus 로고
    • Indole-2-carboxylic acid: A competitive antagonist of potentiation by glycine at the NMDA receptor
    • Huettner JE (1989) Indole-2-carboxylic acid: a competitive antagonist of potentiation by glycine at the NMDA receptor. Science 243:1611-1613.
    • (1989) Science , vol.243 , pp. 1611-1613
    • Huettner, J.E.1
  • 15
    • 0027385330 scopus 로고
    • Multiple structural determinants of voltage-dependent magnesium block in recombinant NMDA receptors
    • Kawajiri S, Dingledine R (1993) Multiple structural determinants of voltage-dependent magnesium block in recombinant NMDA receptors. Neuropharmacology 32:1203-1211.
    • (1993) Neuropharmacology , vol.32 , pp. 1203-1211
    • Kawajiri, S.1    Dingledine, R.2
  • 16
    • 0023754192 scopus 로고
    • Requirement for glycine in activation of NMDA-receptors expressed in Xenopus oocytes
    • Kleckner NW, Dingledine R (1988) Requirement for glycine in activation of NMDA-receptors expressed in Xenopus oocytes. Science 241:835-837.
    • (1988) Science , vol.241 , pp. 835-837
    • Kleckner, N.W.1    Dingledine, R.2
  • 17
    • 0030463423 scopus 로고    scopus 로고
    • Calcium-dependent inactivation of recombinant N-methyl-D-aspartate receptors is NR2 subunit specific
    • Krupp JJ, Vissel B, Heinemann SF, Westbrook GL (1996) Calcium-dependent inactivation of recombinant N-methyl-D-aspartate receptors is NR2 subunit specific. Mol Pharmacol 50:1680-1688.
    • (1996) Mol Pharmacol , vol.50 , pp. 1680-1688
    • Krupp, J.J.1    Vissel, B.2    Heinemann, S.F.3    Westbrook, G.L.4
  • 19
    • 0030991790 scopus 로고    scopus 로고
    • Molecular determinants of agonist discrimination by NMDA receptor subunits: Analysis of the glutamate binding site on the NR2B subunit
    • Laube B, Hirai H, Sturgess M, Betz H, Kuhse J (1997) Molecular determinants of agonist discrimination by NMDA receptor subunits: analysis of the glutamate binding site on the NR2B subunit. Neuron 18:493-503.
    • (1997) Neuron , vol.18 , pp. 493-503
    • Laube, B.1    Hirai, H.2    Sturgess, M.3    Betz, H.4    Kuhse, J.5
  • 20
    • 0027461218 scopus 로고
    • Inactivation of NMDA channels in cultured hippocampal neurons by intracellular calcium
    • Legendre P, Rosenmund C, Westbrook GL 1993 Inactivation of NMDA channels in cultured hippocampal neurons by intracellular calcium., J Neurosci 13:674-684.
    • (1993) J Neurosci , vol.13 , pp. 674-684
    • Legendre, P.1    Rosenmund, C.2    Westbrook, G.L.3
  • 21
    • 0025247748 scopus 로고
    • Glycine decreases desensitization of N-methyl-D-aspartate (NMDA) receptors expressed in Xenopus oocytes and is required for NMDA responses
    • Lerma J, Zukin RS, Bennett MV (1990) Glycine decreases desensitization of N-methyl-D-aspartate (NMDA) receptors expressed in Xenopus oocytes and is required for NMDA responses. Proc Natl Acad Sci USA 87:2354-2358.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 2354-2358
    • Lerma, J.1    Zukin, R.S.2    Bennett, M.V.3
  • 22
    • 0033551327 scopus 로고    scopus 로고
    • Synaptic calcium transients in single spines indicate that NMDA receptors are not saturated
    • Mainen ZF, Malinow R, Svoboda K (1999) Synaptic calcium transients in single spines indicate that NMDA receptors are not saturated. Nature 399:151-155.
    • (1999) Nature , vol.399 , pp. 151-155
    • Mainen, Z.F.1    Malinow, R.2    Svoboda, K.3
  • 23
    • 0025679012 scopus 로고
    • 5,7-Dichlorokynurenic acid, a potent and selective competitive antagonist of the glycine site on NMDA receptors
    • McNamara D, Smith EC, Calligaro DO, O'Malley PJ, McQuaid LA, Dingledine R (1990) 5,7-Dichlorokynurenic acid, a potent and selective competitive antagonist of the glycine site on NMDA receptors. Neurosci Lett 120:17-20.
    • (1990) Neurosci Lett , vol.120 , pp. 17-20
    • McNamara, D.1    Smith, E.C.2    Calligaro, D.O.3    O'Malley, P.J.4    McQuaid, L.A.5    Dingledine, R.6
  • 25
    • 0032732121 scopus 로고    scopus 로고
    • Putative partial agonist 1-aminocyclopropanecarboxylic acid acts concurrently as a glycine-site agonist and a glutamate-site antagonist at N-methyl-D-aspartate receptors
    • Nahum-Levy R, Fossom LH, Skolnick P, Benveniste M (1999) Putative partial agonist 1-aminocyclopropanecarboxylic acid acts concurrently as a glycine-site agonist and a glutamate-site antagonist at N-methyl-D-aspartate receptors. Mol Pharmacol 56:1207-1218.
    • (1999) Mol Pharmacol , vol.56 , pp. 1207-1218
    • Nahum-Levy, R.1    Fossom, L.H.2    Skolnick, P.3    Benveniste, M.4
  • 26
    • 0035029052 scopus 로고    scopus 로고
    • Desensitization of NMDA receptor channels is modulated by glutamate agonists
    • Nahum-Levy R, Lipinski D, Shavit S, Benveniste M (2001) Desensitization of NMDA receptor channels is modulated by glutamate agonists. Biophys J 80:2152-2166.
    • (2001) Biophys J , vol.80 , pp. 2152-2166
    • Nahum-Levy, R.1    Lipinski, D.2    Shavit, S.3    Benveniste, M.4
  • 27
    • 0001520306 scopus 로고
    • Zur Kinetick der in Lösung befindlichen Körper: Theorie der Diffusion
    • Nernst W (1888) Zur Kinetick der in Lösung befindlichen Körper: Theorie der Diffusion. Z Phys Chem 2:613-637.
    • (1888) Z Phys Chem , vol.2 , pp. 613-637
    • Nernst, W.1
  • 28
    • 0031912995 scopus 로고    scopus 로고
    • Glutamate receptors in the mammalian central nervous system
    • Ozawa S, Kamiya H, Tsuzuki K (1998) Glutamate receptors in the mammalian central nervous system. Prog Neurobiol 54:581-618.
    • (1998) Prog Neurobiol , vol.54 , pp. 581-618
    • Ozawa, S.1    Kamiya, H.2    Tsuzuki, K.3
  • 29
    • 0028867740 scopus 로고
    • Glycine-independent and subunit-specific potentiation of NMDA responses by extracellular Mg2+
    • Paoletti P, Neyton J, Ascher P (1995) Glycine-independent and subunit-specific potentiation of NMDA responses by extracellular Mg2+. Neuron 15:1109-1120.
    • (1995) Neuron , vol.15 , pp. 1109-1120
    • Paoletti, P.1    Neyton, J.2    Ascher, P.3
  • 30
    • 0027732736 scopus 로고
    • Agonist response kinetics of N-methyl-D-aspartate receptors in neurons cultured from rat cerebral cortex and cerebellum: Evidence for receptor heterogeneity
    • Priestley T, Kemp JA (1993) Agonist response kinetics of N-methyl-D-aspartate receptors in neurons cultured from rat cerebral cortex and cerebellum: evidence for receptor heterogeneity. Mol Pharmacol 44:1252-1257.
    • (1993) Mol Pharmacol , vol.44 , pp. 1252-1257
    • Priestley, T.1    Kemp, J.A.2
  • 31
    • 0028606309 scopus 로고
    • Kinetic study of the interactions between the glutamate and glycine recognition sites on the N-methyl-D-aspartic acid receptor complex
    • Priestley T, Kemp JA (1994) Kinetic study of the interactions between the glutamate and glycine recognition sites on the N-methyl-D-aspartic acid receptor complex. Mol Pharmacol 46:1191-1196.
    • (1994) Mol Pharmacol , vol.46 , pp. 1191-1196
    • Priestley, T.1    Kemp, J.A.2
  • 32
    • 0025360254 scopus 로고
    • Glycine-insensitive desensitization of NMDA responses in cultured mouse embryonic neurons
    • Sather W, Johnson JW, Henderson G, Ascher P (1990) Glycine-insensitive desensitization of NMDA responses in cultured mouse embryonic neurons. Neuron 4:725-731.
    • (1990) Neuron , vol.4 , pp. 725-731
    • Sather, W.1    Johnson, J.W.2    Henderson, G.3    Ascher, P.4
  • 33
    • 0031017261 scopus 로고    scopus 로고
    • Coupling of permeation and gating in an NMDA-channel pore mutant
    • Schneggenburger R, Ascher P (1997) Coupling of permeation and gating in an NMDA-channel pore mutant. Neuron 18:167-177.
    • (1997) Neuron , vol.18 , pp. 167-177
    • Schneggenburger, R.1    Ascher, P.2
  • 34
    • 0027965033 scopus 로고
    • Regulation of glycine-insensitive desensitization of the NMDA receptor in outside-out patches
    • Tong G, Jahr CE (1994) Regulation of glycine-insensitive desensitization of the NMDA receptor in outside-out patches. J Neurophysiol 72:754-761.
    • (1994) J Neurophysiol , vol.72 , pp. 754-761
    • Tong, G.1    Jahr, C.E.2
  • 35
    • 0025006846 scopus 로고
    • Modulation of N-methyl-D-aspartic acid receptor desensitization by glycine in mouse cultured hippocampal neurones
    • Vyklicky Jr L, Benveniste M, Mayer ML (1990) Modulation of N-methyl-D-aspartic acid receptor desensitization by glycine in mouse cultured hippocampal neurones. J Physiol (Lond) 428:313-331.
    • (1990) J Physiol (Lond) , vol.428 , pp. 313-331
    • Vyklicky Jr., L.1    Benveniste, M.2    Mayer, M.L.3
  • 36
    • 0032480890 scopus 로고    scopus 로고
    • Gain control of NMDA-receptor currents by intracellular sodium
    • Yu XM, Salter MW (1998) Gain control of NMDA-receptor currents by intracellular sodium. Nature 396:469-474.
    • (1998) Nature , vol.396 , pp. 469-474
    • Yu, X.M.1    Salter, M.W.2
  • 37
    • 0035005299 scopus 로고    scopus 로고
    • 2+ block of the N-methyl-D-aspartate receptor channel
    • 2+ block of the N-methyl-D-aspartate receptor channel. J Gen Physiol 117:275-286.
    • (2001) J Gen Physiol , vol.117 , pp. 275-286
    • Zhu, Y.1    Auerbach, A.2


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